Page last updated: 2024-09-03

sc 51089 and ibuprofen

sc 51089 has been researched along with ibuprofen in 3 studies

Compound Research Comparison

Studies
(sc 51089)
Trials
(sc 51089)
Recent Studies (post-2010)
(sc 51089)
Studies
(ibuprofen)
Trials
(ibuprofen)
Recent Studies (post-2010) (ibuprofen)
4111910,2451,7814,267

Protein Interaction Comparison

ProteinTaxonomysc 51089 (IC50)ibuprofen (IC50)
Prostaglandin G/H synthase 1 Bos taurus (cattle)2.9
Prostaglandin G/H synthase 2 Bos taurus (cattle)1.1
AlbuminBos taurus (cattle)3
Prostaglandin G/H synthase 1Ovis aries (sheep)4.0919
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.22
Prostaglandin G/H synthase 1Homo sapiens (human)1.6273
Caspase-1Homo sapiens (human)7.2667
Substance-P receptorCavia porcellus (domestic guinea pig)1.1
Prostaglandin G/H synthase 2Homo sapiens (human)3.0687
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)1.3
Aldo-keto reductase family 1 member C3Homo sapiens (human)10
Caspase-3Homo sapiens (human)7.2667
Caspase-4Homo sapiens (human)7.2667
4-aminobutyrate aminotransferase, mitochondrialRattus norvegicus (Norway rat)1.1
Caspase-5Homo sapiens (human)7.2667
Caspase-9Homo sapiens (human)7.2667
Prostaglandin G/H synthase 2Ovis aries (sheep)1.1375
Mu-type opioid receptorCavia porcellus (domestic guinea pig)2.9
Fatty-acid amide hydrolase 1Rattus norvegicus (Norway rat)5
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.54
Solute carrier family 22 member 6Homo sapiens (human)8
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)1.3

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hagen, TJ; Hallinan, EA; Husa, RK; Rafferty, MF; Rao, SN; Reichman, M; Savage, MA; Stapelfeld, A; Tsymbalov, S; vanHoeck, JP1
Collins, C; Henderson, SC; Herrick, B; Klausner, AP; Koo, HP; Miner, AS; Ratz, PH1
Ariff, MA; Mathivanan, P; Parker, R; Rudra, T; Taub, M1

Other Studies

3 other study(ies) available for sc 51089 and ibuprofen

ArticleYear
N-substituted dibenzoxazepines as analgesic PGE2 antagonists.
    Journal of medicinal chemistry, 1993, Oct-29, Volume: 36, Issue:22

    Topics: Analgesics; Animals; Chemical Phenomena; Chemistry, Physical; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dibenzoxazepines; Dinoprostone; Guinea Pigs; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Nociceptors; Solubility; Structure-Activity Relationship; Water

1993
Potential for control of detrusor smooth muscle spontaneous rhythmic contraction by cyclooxygenase products released by interstitial cells of Cajal.
    Journal of cellular and molecular medicine, 2009, Volume: 13, Issue:9B

    Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Hydrazines; Ibuprofen; Indomethacin; Interstitial Cells of Cajal; Muscle Contraction; Muscle, Smooth; Oxazepines; Prostaglandins; Rabbits; Urinary Bladder; Vimentin

2009
Antagonism of the prostaglandin E2 EP1 receptor in MDCK cells increases growth through activation of Akt and the epidermal growth factor receptor.
    American journal of physiology. Renal physiology, 2014, Sep-01, Volume: 307, Issue:5

    Topics: Animals; Bridged Bicyclo Compounds; Caproates; Cell Proliferation; Dogs; ErbB Receptors; Heterocyclic Compounds, 3-Ring; Hydrazines; Ibuprofen; Kidney; Madin Darby Canine Kidney Cells; Oxazepines; Proto-Oncogene Proteins c-akt; Quinazolines; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Tyrphostins

2014