Page last updated: 2024-09-03

sc 51089 and hydrazine

sc 51089 has been researched along with hydrazine in 40 studies

Compound Research Comparison

Studies (sc 51089)	Trials (sc 51089)	Recent Studies (post-2010) (sc 51089)	Studies (hydrazine)	Trials (hydrazine)	Recent Studies (post-2010) (hydrazine)
41	1	19	12,034	330	3,193

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (15.00)	18.2507
2000's	13 (32.50)	29.6817
2010's	21 (52.50)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Green, PG; Ho, T; Khasar, SG; Levine, JD	1
Malmberg, AB; Rafferty, MF; Yaksh, TL	1
Beck, D; Cavalier, R; Herin, M; Lee, K; Lesne, M; Li, A; Roba, J; Vandenberghe, Y; Verbeke, N	1
Hagen, TJ; Hallinan, EA; Husa, RK; Lee, AC; Savage, MA; Stapelfeld, A; Tsymbalov, S	1
Kato, S; Takeuchi, K; Ukawa, H; Yagi, K	1
Baloch, M; Clapp, LH; Hall, S; Turcato, S	1
Hosoda, Y; Iwanaga, T; Kuwahara, A; Winarto, A	1
Maruyama, T; Ohuchida, S	1
Glaser, S; Hennerbichler, S; Juan, H; Sametz, W; Wintersteiger, R	1
Hagen, TJ; Hallinan, EA; Savage, MA; Stapelfeld, A; Tsymbalov, S	1
Craib, SJ; Ellington, HC; Pertwee, RG; Ross, RA	1
Heinemann, A; Holzer, P; Peskar, BA; Shahbazian, A	1
Hamasaki, Y; Ishii, K; Matsuo, M; Yoshida, N; Zaitsu, M	1
Matlhagela, K; Taub, M	1
Cavalié, A; Meves, H; Philipp, SE	1
Chou, T; Iadecola, C; Qian, L; Zhou, P	1
Abe, T; Anrather, J; Iadecola, C; Kunz, A; Shimamura, M; Zhou, P	1
Black, JD; Carlson, NG; Hill, KE; Hille, J; Redd, JW; Rojas, MA; Rose, JW	1
Collins, C; Henderson, SC; Herrick, B; Klausner, AP; Koo, HP; Miner, AS; Ratz, PH	1
Fukumoto, K; Moriyama, Y; Takagi, N; Takeo, S; Tanonaka, K; Yamamoto, R	1
Fischborn, SV; Potschka, H; Soerensen, J	1
Applegate, R; Fathali, N; Jadhav, V; Khatibi, NH; Martin, R; Matus, B; Tang, J; Zhang, JH	1
Anacker, C; Andreasson, K; Suarez-Mier, GB; Taniguchi, H; Wang, Q	1
Dobrowolski, P; Doré, S; Kapoor, N; Kim, YT; Langer, J; Li, RC; Maruyama, T; Narumiya, S; Yocum, J; Zhen, G	1
Liu, ML; Liu, X; Pei, LC; Zhang, YN; Zhang, YQ	1
Anrather, J; Burmeister, MA; Cao, X; Davisson, RL; Guruju, MR; Iadecola, C; Peterson, JR; Wang, G; Young, CN	1
Keene, CD; Li, X; Montine, KS; Montine, TJ; Rose, SE	1
Anrather, J; Capone, C; Casolla, B; Iadecola, C; Kurinami, H; Qian, L; Shimamura, M; Zhou, P	1
Northrop, NA; Yamamoto, BK	1
Chen, J; Chen, L; Shen, X; Wang, G; Xu, X; Yao, X; Zhou, R; Zhu, Z	1
Alberch, J; Anglada-Huguet, M; Giralt, A; Martín, ED; Xifró, X; Zamora-Moratalla, A	1
Ariff, MA; Mathivanan, P; Parker, R; Rudra, T; Taub, M	1
Doré, S; Fazal, JA; Glushakov, AV; Narumiya, S	1
Chang, CF; Gao, Y; Han, X; Hou, Z; Li, Q; Maruyama, T; Wang, J; Wu, H; Wu, T; Zhang, J; Zhao, X	1
Amadio, P; Amato, M; Baldassarre, D; Barbieri, SS; Gianellini, S; Squellerio, I; Tarantino, E; Tremoli, E; Weksler, BB; Zacchi, E	1
Ahmad, AS; Dang, A; Doré, S; Greene, E; Leclerc, JL; Singh, N; Soshnik-Schierling, L	1
Ahmad, AS; Candelario-Jalil, E; DeMars, KM; Doré, S; Frankowski, JC; Hawkins, KE; Leclerc, JL; Yang, C	1
Chiaia, N; Collins, SA; Gudelsky, GA; Huff, C; Yamamoto, BK	1
Kadekawa, K; Kakizaki, H; Majima, T; Shimizu, T; Tyagi, P; Wada, N; Yoshimura, N	1
Liu, W; Ma, N; Niu, JC; Wang, PJ	1

Reviews

2 review(s) available for sc 51089 and hydrazine

Article	Year
[Selective agonists and antagonists for prostaglandin E2 receptor subtypes]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2000, Volume: 45, Issue:6 Suppl Topics: Acetates; Animals; Benzhydryl Compounds; Biphenyl Compounds; Dinoprostone; Drug Design; Humans; Hydrazines; Oxazepines; Receptors, Prostaglandin E	2000
Antagonism of neuronal prostaglandin E(2) receptor subtype 1 mitigates amyloid β neurotoxicity in vitro. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2013, Volume: 8, Issue:1 Topics: Amyloid beta-Peptides; Animals; Blotting, Western; Calcium Channel Blockers; Cell Line, Tumor; Cells, Cultured; Coloring Agents; Dinoprostone; Humans; Hydrazines; Mice; Mice, Inbred C57BL; Neurons; Neurotoxicity Syndromes; Nimodipine; Oxazepines; Peptide Fragments; Prostaglandin Antagonists; Receptors, Prostaglandin E, EP1 Subtype; Tetrazolium Salts; Thiazoles	2013

Article

Year

[Selective agonists and antagonists for prostaglandin E2 receptor subtypes].

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2000, Volume: 45, Issue:6 Suppl

Topics: Acetates; Animals; Benzhydryl Compounds; Biphenyl Compounds; Dinoprostone; Drug Design; Humans; Hydrazines; Oxazepines; Receptors, Prostaglandin E

2000

Antagonism of neuronal prostaglandin E(2) receptor subtype 1 mitigates amyloid β neurotoxicity in vitro.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2013, Volume: 8, Issue:1

Topics: Amyloid beta-Peptides; Animals; Blotting, Western; Calcium Channel Blockers; Cell Line, Tumor; Cells, Cultured; Coloring Agents; Dinoprostone; Humans; Hydrazines; Mice; Mice, Inbred C57BL; Neurons; Neurotoxicity Syndromes; Nimodipine; Oxazepines; Peptide Fragments; Prostaglandin Antagonists; Receptors, Prostaglandin E, EP1 Subtype; Tetrazolium Salts; Thiazoles

2013

Trials

1 trial(s) available for sc 51089 and hydrazine

Article	Year
Production of prostaglandin E2 induced by cigarette smoke modulates tissue factor expression and activity in endothelial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015, Volume: 29, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Animals; Dinoprostone; Endothelial Cells; Female; Gene Expression Regulation; Humans; Hydrazines; Interleukin-1beta; Male; Mice; Middle Aged; Myocardium; Oxazepines; Sirtuin 1; Smoking; Thromboplastin; Thrombosis; Xanthones	2015

Article

Year

Production of prostaglandin E2 induced by cigarette smoke modulates tissue factor expression and activity in endothelial cells.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015, Volume: 29, Issue:9

Topics: Adult; Aged; Aged, 80 and over; Animals; Dinoprostone; Endothelial Cells; Female; Gene Expression Regulation; Humans; Hydrazines; Interleukin-1beta; Male; Mice; Middle Aged; Myocardium; Oxazepines; Sirtuin 1; Smoking; Thromboplastin; Thrombosis; Xanthones

2015

Other Studies

37 other study(ies) available for sc 51089 and hydrazine

Article	Year
Comparison of prostaglandin E1- and prostaglandin E2-induced hyperalgesia in the rat. Neuroscience, 1994, Volume: 62, Issue:2 Topics: Alprostadil; Analgesics; Animals; Diabetes Mellitus, Experimental; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hindlimb; Hydrazines; Hyperalgesia; Male; Oxazepines; Pain; Rats; Rats, Sprague-Dawley	1994
Antinociceptive effect of spinally delivered prostaglandin E receptor antagonists in the formalin test on the rat. Neuroscience letters, 1994, May-23, Volume: 173, Issue:1-2 Topics: Analgesics; Animals; Behavior, Animal; Dibenzoxazepines; Dose-Response Relationship, Drug; Formaldehyde; Hydrazines; Injections, Spinal; Male; Oxazepines; Pain Measurement; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Spinal Cord	1994
Comparative metabolism of SC-42867 and SC-51089, two PGE2 antagonists, in rat and human hepatocyte cultures. Xenobiotica; the fate of foreign compounds in biological systems, 1994, Volume: 24, Issue:1 Topics: Adult; Analgesics; Animals; Carbon Radioisotopes; Cells, Cultured; Dinoprostone; Humans; Hydrazines; Liver; Male; Oxazepines; Rats; Rats, Sprague-Dawley	1994
Aminoacetyl moiety as a potential surrogate for diacylhydrazine group of SC-51089, a potent PGE2 antagonist, and its analogs. Journal of medicinal chemistry, 1996, Jan-19, Volume: 39, Issue:2 Topics: Analgesics; Animals; Cells, Cultured; Dinoprostone; Guinea Pigs; Hydrazines; Ileum; In Vitro Techniques; Liver; Magnetic Resonance Spectroscopy; Oxazepines; Prostaglandin Antagonists; Rats	1996
Roles of prostaglandin E-receptor subtypes in gastric and duodenal bicarbonate secretion in rats. Gastroenterology, 1997, Volume: 113, Issue:5 Topics: 1-Methyl-3-isobutylxanthine; Animals; Bicarbonates; Calcium; Dinoprostone; Duodenum; Gastric Mucosa; Hydrazines; Male; Oxazepines; Prostaglandins E; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Verapamil	1997
Evidence that Ca2+-activated K+ channels play a major role in mediating the vascular effects of iloprost and cicaprost. European journal of pharmacology, 1998, Sep-04, Volume: 356, Issue:2-3 Topics: Animals; Antineoplastic Agents; Calcium; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Guinea Pigs; Hydrazines; Iloprost; Isoproterenol; Male; Muscle, Smooth, Vascular; Oxazepines; Phenylephrine; Potassium Channel Blockers; Potassium Channels; Prostaglandin Antagonists; Tetraethylammonium; Vasodilation; Vasodilator Agents	1998
Mode of action of ANG II on ion transport in guinea pig distal colon. American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 278, Issue:4 Topics: Angiotensin II; Animals; Atropine; Biological Transport; Bumetanide; Chlorides; Colon; Dinoprostone; Electric Conductivity; Guinea Pigs; Hydrazines; Immunohistochemistry; Ions; Male; Neurokinin-1 Receptor Antagonists; Oxazepines; Prostaglandin Antagonists; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrodotoxin	2000
Characterization of prostanoid receptors mediating actions of the isoprostanes, 8-iso-PGE(2) and 8-iso-PGF(2alpha), in some isolated smooth muscle preparations. British journal of pharmacology, 2000, Volume: 130, Issue:8 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta, Thoracic; Bridged Bicyclo Compounds, Heterocyclic; Dinoprost; Dinoprostone; Dioxanes; Dose-Response Relationship, Drug; F2-Isoprostanes; Fatty Acids, Unsaturated; Female; Gastric Fundus; Guinea Pigs; Hydrazines; Ileum; In Vitro Techniques; Isoprostanes; Muscle Contraction; Muscle, Smooth; Oxazepines; Prostaglandin Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Thromboxane; Vasoconstriction; Vasoconstrictor Agents	2000
2,4-Disubstituted oxazoles and thiazoles as latent pharmacophores for diacylhydrazine of SC-51089, a potent PGE2 antagonist. Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:1 Topics: Dinoprostone; Hydrazines; Oxazepines; Oxazoles; Thiazoles	2001
A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus. British journal of pharmacology, 2001, Volume: 134, Issue:1 Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Bronchi; Calcium Channel Blockers; Capsaicin; Cyclohexanols; Dose-Response Relationship, Drug; Endocannabinoids; Fatty Acids, Unsaturated; Guinea Pigs; Hydrazines; In Vitro Techniques; Indomethacin; Lipoxygenase; Muscle Contraction; Oxazepines; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Drug; Rimonabant; Thiorphan	2001
Differential peristaltic motor effects of prostanoid (DP, EP, IP, TP) and leukotriene receptor agonists in the guinea-pig isolated small intestine. British journal of pharmacology, 2002, Volume: 137, Issue:7 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dinoprostone; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Female; Guinea Pigs; Hydantoins; Hydrazines; Iloprost; In Vitro Techniques; Intestine, Small; Leukotriene Antagonists; Leukotriene D4; Male; Oxazepines; Peristalsis; Prostaglandin D2; Prostaglandins A; Receptors, Leukotriene; Receptors, Prostaglandin; Xanthenes; Xanthones; Yohimbine	2002
Inhibition of human glioma cell growth by a PHS-2 inhibitor, NS398, and a prostaglandin E receptor subtype EP1-selective antagonist, SC51089. Journal of neuro-oncology, 2004, Volume: 66, Issue:3 Topics: Animals; Brain Neoplasms; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Female; Glioma; Humans; Hydrazines; Isoenzymes; Membrane Proteins; Mice; Mice, SCID; Nitrobenzenes; Oxazepines; Prostaglandin-Endoperoxide Synthases; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Sulfonamides; Transplantation, Heterologous; Tumor Cells, Cultured; Xanthones	2004
Involvement of EP1 and EP2 receptors in the regulation of the Na,K-ATPase by prostaglandins in MDCK cells. Prostaglandins & other lipid mediators, 2006, Volume: 79, Issue:1-2 Topics: Alprostadil; Animals; Cell Line; Dinoprostone; Dogs; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hydrazines; Ion Transport; Kidney Tubules, Distal; Oxazepines; Prostaglandin Antagonists; Protein Kinase C; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Sodium-Potassium-Exchanging ATPase; Xanthones	2006
ONO-54918-07, a stable prostacyclin analogue, mimics the effect of prostaglandin PGE1 on NG108-15 cells. Naunyn-Schmiedeberg's archives of pharmacology, 2007, Volume: 376, Issue:3 Topics: Alprostadil; Animals; Benzofurans; Calcium; Cell Line, Tumor; Cinnamates; Cytosol; Dose-Response Relationship, Drug; Hydrazines; Mice; Oxazepines; Patch-Clamp Techniques; Propionates; Prostaglandins F; Receptors, Epoprostenol; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Vasodilator Agents	2007
Neuroprotection by PGE2 receptor EP1 inhibition involves the PTEN/AKT pathway. Neurobiology of disease, 2008, Volume: 29, Issue:3 Topics: Animals; Cell Survival; Dinoprostone; Hippocampus; Hydrazines; Mice; Neuroprotective Agents; Organ Culture Techniques; Oxazepines; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Signal Transduction	2008
The neuroprotective effect of prostaglandin E2 EP1 receptor inhibition has a wide therapeutic window, is sustained in time and is not sexually dimorphic. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2009, Volume: 29, Issue:1 Topics: Animals; Body Weight; Brain Ischemia; Dinoprostone; Dose-Response Relationship, Drug; Female; Hydrazines; Male; Mice; Neuroprotective Agents; Oxazepines; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Sex Characteristics; Time Factors; Treatment Outcome	2009
Microglial inhibition of neuroprotection by antagonists of the EP1 prostaglandin E2 receptor. Journal of neuroinflammation, 2009, Feb-17, Volume: 6 Topics: Animals; Astrocytes; Bridged Bicyclo Compounds; Caproates; Cell Death; Cells, Cultured; Coculture Techniques; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Hydrazines; Mice; Microglia; Microscopy, Confocal; N-Methylaspartate; Neurons; Neuroprotective Agents; Oxazepines; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype	2009
Potential for control of detrusor smooth muscle spontaneous rhythmic contraction by cyclooxygenase products released by interstitial cells of Cajal. Journal of cellular and molecular medicine, 2009, Volume: 13, Issue:9B Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Hydrazines; Ibuprofen; Indomethacin; Interstitial Cells of Cajal; Muscle Contraction; Muscle, Smooth; Oxazepines; Prostaglandins; Rabbits; Urinary Bladder; Vimentin	2009
Prostanoid EP1 receptor antagonist reduces blood-brain barrier leakage after cerebral ischemia. European journal of pharmacology, 2010, Aug-25, Volume: 640, Issue:1-3 Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Capillaries; Capillary Permeability; Fluorescein-5-isothiocyanate; Hydrazines; Male; Membrane Proteins; Occludin; Oxazepines; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Serum Albumin; Tyrosine	2010
Targeting the prostaglandin E2 EP1 receptor and cyclooxygenase-2 in the amygdala kindling model in mice. Epilepsy research, 2010, Volume: 91, Issue:1 Topics: Amygdala; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Hydrazines; Kindling, Neurologic; Male; Mice; Oxazepines; Receptors, Prostaglandin E, EP1 Subtype	2010
Prostaglandin E2 EP1 receptor inhibition fails to provide neuroprotection in surgically induced brain-injured mice. Acta neurochirurgica. Supplement, 2011, Volume: 111 Topics: Animals; Brain Edema; Brain Injuries; Cell Death; Disease Models, Animal; Dose-Response Relationship, Drug; Functional Laterality; Hydrazines; Male; Mice; Nervous System Diseases; Neuroprotective Agents; Neurosurgical Procedures; Oxazepines; Receptors, Prostaglandin E, EP1 Subtype; Time Factors; Treatment Failure	2011
Function of prostaglandin E2 EP receptors in the acute outcome of rodent hypoxic ischemic encephalopathy. Neuroscience letters, 2011, Oct-31, Volume: 504, Issue:3 Topics: Animals; Animals, Newborn; Cells, Cultured; Dinoprostone; Endothelial Cells; Glucose; Hippocampus; Hydrazines; Hypoxia-Ischemia, Brain; Misoprostol; Neurons; Oxazepines; Oxygen; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction	2011
PGE2 EP1 receptor exacerbated neurotoxicity in a mouse model of cerebral ischemia and Alzheimer's disease. Neurobiology of aging, 2012, Volume: 33, Issue:9 Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Brain; Brain Ischemia; Calcium; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glucose; Hippocampus; Humans; Hydrazines; Hypoxia; Male; Mice; Mice, Transgenic; Neurons; Neurotoxicity Syndromes; Oxazepines; Peptide Fragments; Presenilin-1; Receptors, Prostaglandin E, EP1 Subtype	2012
Prostaglandin E2 receptor 1 activity regulates cell survival following hypoxia in cultured rat cortical neurons. Neuroscience letters, 2012, Feb-02, Volume: 508, Issue:1 Topics: Analysis of Variance; Animals; Annexin A5; Caspase 3; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclin D1; Dinoprostone; Dose-Response Relationship, Drug; Embryo, Mammalian; Hydrazines; Hypoxia; Neurons; Oxazepines; Oxygen; Rats; Rats, Wistar; Receptors, Prostaglandin E, EP1 Subtype; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation	2012
Angiotensin II-dependent hypertension requires cyclooxygenase 1-derived prostaglandin E2 and EP1 receptor signaling in the subfornical organ of the brain. Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:4 Topics: Angiotensin II; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Hydrazines; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxazepines; Reactive Oxygen Species; Receptor Cross-Talk; Receptors, Prostaglandin E, EP1 Subtype; Signal Transduction; Subfornical Organ	2012
Prostaglandin E2 type 1 receptors contribute to neuronal apoptosis after transient forebrain ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2013, Volume: 33, Issue:8 Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Blotting, Western; CA1 Region, Hippocampal; Calcineurin; Calcineurin Inhibitors; Caspase 3; Dinoprostone; Hydrazines; Immunohistochemistry; Ischemic Attack, Transient; Mice; Mice, Inbred C57BL; Neurons; Oncogene Protein v-akt; Oxazepines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Transport; Receptors, Prostaglandin E, EP1 Subtype	2013
Cyclooxygenase activity contributes to the monoaminergic damage caused by serial exposure to stress and methamphetamine. Neuropharmacology, 2013, Volume: 72 Topics: Analysis of Variance; Animals; Biogenic Monoamines; Body Temperature; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Gene Expression Regulation; Hippocampus; Hydrazines; Male; Methamphetamine; Oxazepines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Stress, Psychological	2013
Blockage of progesterone receptor effectively protects pancreatic islet beta cell viability. Steroids, 2013, Volume: 78, Issue:10 Topics: Animals; Apoptosis; Cell Survival; Cytokines; Drug Evaluation, Preclinical; Gene Knockdown Techniques; HEK293 Cells; Humans; Hydrazines; Hypoglycemic Agents; Inflammation Mediators; Insulin-Secreting Cells; MCF-7 Cells; Mice; Oxazepines; Proto-Oncogene Proteins c-akt; Receptors, Progesterone; Transcription, Genetic	2013
Prostaglandin E2 EP1 receptor antagonist improves motor deficits and rescues memory decline in R6/1 mouse model of Huntington's disease. Molecular neurobiology, 2014, Volume: 49, Issue:2 Topics: Animals; Disease Models, Animal; Huntington Disease; Hydrazines; Male; Memory Disorders; Mice; Mice, Inbred CBA; Mice, Transgenic; Motor Skills Disorders; Oxazepines; Receptors, Prostaglandin E, EP1 Subtype	2014
Antagonism of the prostaglandin E2 EP1 receptor in MDCK cells increases growth through activation of Akt and the epidermal growth factor receptor. American journal of physiology. Renal physiology, 2014, Sep-01, Volume: 307, Issue:5 Topics: Animals; Bridged Bicyclo Compounds; Caproates; Cell Proliferation; Dogs; ErbB Receptors; Heterocyclic Compounds, 3-Ring; Hydrazines; Ibuprofen; Kidney; Madin Darby Canine Kidney Cells; Oxazepines; Proto-Oncogene Proteins c-akt; Quinazolines; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Tyrphostins	2014
Role of the prostaglandin E2 EP1 receptor in traumatic brain injury. PloS one, 2014, Volume: 9, Issue:11 Topics: Animals; Brain; Brain Injuries; Hydrazines; Male; Mice, Inbred C57BL; Mice, Knockout; Oxazepines; Receptors, Prostaglandin E, EP1 Subtype	2014
Toxic role of prostaglandin E2 receptor EP1 after intracerebral hemorrhage in mice. Brain, behavior, and immunity, 2015, Volume: 46 Topics: Alprostadil; Animals; Brain; Cerebral Hemorrhage; Female; Hydrazines; Male; Mice; Microglia; Neurons; Oxazepines; Receptors, Prostaglandin E, EP1 Subtype	2015
Intracerebral hemorrhage outcomes following selective blockade or stimulation of the PGE2 EP1 receptor. BMC neuroscience, 2015, Aug-01, Volume: 16 Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain; Cerebral Hemorrhage; Collagenases; Disease Models, Animal; Gliosis; Hydrazines; Iron; Leukocytes; Male; Mice, Inbred C57BL; Microglia; Neuroimmunomodulation; Neuroprotective Agents; Oxazepines; Receptors, Prostaglandin E, EP1 Subtype; Recovery of Function	2015
Detrimental role of the EP1 prostanoid receptor in blood-brain barrier damage following experimental ischemic stroke. Scientific reports, 2015, Dec-09, Volume: 5 Topics: Animals; Blood-Brain Barrier; Brain Infarction; Disease Models, Animal; Endothelial Cells; Gene Expression; Gene Knockout Techniques; Hydrazines; Male; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Neurons; Neutrophil Infiltration; Oxazepines; Permeability; Proteolysis; Rats; Receptors, Prostaglandin E, EP1 Subtype; Stroke; Tight Junction Proteins	2015
3,4-methylenedioxymethamphetamine increases excitability in the dentate gyrus: role of 5HT2A receptor-induced PGE2 signaling. Journal of neurochemistry, 2016, Volume: 136, Issue:5 Topics: Animals; Central Nervous System Stimulants; Dentate Gyrus; Dinoprostone; Glutamic Acid; Hippocampus; Hydrazines; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Oxazepines; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Signal Transduction	2016
Urodynamic effects of intravenous and intrathecal administration of E-series prostaglandin 1 receptor antagonist on detrusor overactivity in rats with spinal cord injury. Neurourology and urodynamics, 2018, Volume: 37, Issue:1 Topics: Administration, Intravenous; Animals; Female; Hydrazines; Oxazepines; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E, EP1 Subtype; Spinal Cord Injuries; Urinary Bladder, Overactive; Urodynamics	2018
EP1 receptor is involved in prostaglandin E2-induced osteosarcoma growth. Bosnian journal of basic medical sciences, 2019, Aug-20, Volume: 19, Issue:3 Topics: Animals; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dinoprostone; Gene Silencing; Humans; Hydrazines; Mice; Mice, Nude; Osteosarcoma; Oxazepines; Receptors, Prostaglandin E, EP1 Subtype; Xenograft Model Antitumor Assays	2019