sc 4453 and ouabain
sc 4453 has been researched along with ouabain in 4 studies
*Ouabain: A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE. [MeSH]
*Ouabain: A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE. [MeSH]
Compound Research Comparison
| Studies (sc 4453) | Trials (sc 4453) | Recent Studies (post-2010) (sc 4453) | Studies (ouabain) | Trials (ouabain) | Recent Studies (post-2010) (ouabain) |
|---|---|---|---|---|---|
| 10 | 0 | 0 | 16,357 | 72 | 747 |
Protein Interaction Comparison
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Chopra, A; Dudani, AK; Gupta, RS | 1 |
| Chopra, A; Gupta, RS; Trott, AB | 1 |
| Chopra, A; Gupta, RS | 2 |
Other Studies
4 other study(ies) available for sc 4453 and ouabain
| Article | Year |
|---|---|
Cross-resistance and biochemical characteristics of second-step mutants of HeLa cells resistant to cardiac glycosides.
Topics: Animals; Cardiac Glycosides; Cell Line; Cricetinae; Digoxin; Drug Resistance; Gene Amplification; HeLa Cells; Humans; Mutation; Nucleic Acid Hybridization; Ouabain; Rubidium Radioisotopes; Sodium-Potassium-Exchanging ATPase; Transcription, Genetic | 1990 |
Development of a specific assay for cardiac glycoside-like compounds based on cross-resistance of human cell mutants.
Topics: Cardiac Glycosides; Cell Division; Cell Survival; Digoxin; Drug Resistance; HeLa Cells; Humans; Mutation; Ouabain; Structure-Activity Relationship | 1989 |
Cross-resistance and biochemical studies with two classes of HeLa cell mutants resistant to cardiac glycosides. The unusual behavior of cardenolide SC4453.
Topics: Abietanes; Alkaloids; Cardenolides; Cardiac Glycosides; Digoxin; Dose-Response Relationship, Drug; Drug Resistance; HeLa Cells; Humans; Mutation; Ouabain; Rubidium; Sodium-Potassium-Exchanging ATPase | 1985 |
Biochemical and cross-resistance studies with HeLa cell mutants resistant to cardiac glycoside SC4453. Regulation of the resistant form of Na+/K+-ATPase in the mutant cells.
Topics: Cardiac Glycosides; Digoxin; Drug Resistance; HeLa Cells; Humans; Membrane Proteins; Ouabain; Rubidium; Selection, Genetic; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship | 1986 |