Compounds > sc 41930
Page last updated: 2024-09-02

sc 41930 and mocetinostat

sc 41930 has been researched along with mocetinostat in 11 studies

Compound Research Comparison

Studies
(sc 41930)		Trials
(sc 41930)		Recent Studies (post-2010)
(sc 41930)		Studies
(mocetinostat)		Trials
(mocetinostat)		Recent Studies (post-2010) (mocetinostat)
540021,7353908,606

Protein Interaction Comparison

ProteinTaxonomysc 41930 (IC50)mocetinostat (IC50)
Histone deacetylase 3Homo sapiens (human)0.7851
Nuclear receptor corepressor 1Homo sapiens (human)0.022
Cytochrome P450 3A4Homo sapiens (human)0.57
Cytochrome P450 2D6Homo sapiens (human)0.102
Cytochrome P450 2C19Homo sapiens (human)0.102
Histone deacetylase 4Homo sapiens (human)0.5717
Histone deacetylase 1Homo sapiens (human)0.3433
Histone deacetylase 7Homo sapiens (human)0.6725
Histone deacetylase 2Homo sapiens (human)0.3537
Histone deacetylase 11 Homo sapiens (human)0.6386
Histone deacetylase 8Homo sapiens (human)0.6725
Histone deacetylase 6Homo sapiens (human)0.5717
Histone deacetylase 5Homo sapiens (human)0.6725
Nuclear receptor corepressor 2Homo sapiens (human)0.045

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's8 (72.73)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McCafferty, DM; Rioux, KJ; Wallace, JL1
Gaginella, TS; Levin, S; Tamai, H1
Anglin, CP; Fretland, DJ; Gaginella, TS; Widomski, DL1
Anglin, CP; Fretland, DJ; Gaginella, TS; Levin, S; Widomski, DL1
Djuric, SW; Fretland, DJ; Gaginella, TS; Levin, S; Shone, RL; Tsai, BS; Widomski, D; Zemaitis, JM1
Butchko, GM; Collins, PW; Djuric, SW; Fretland, DJ; Jones, PH; Keith, RH; Shone, RL; Tsai, BS; Villani-Price, D; Zemaitis, JM1
Bauer, RF; Djurić, SW; Fretland, DJ; Levin, S; Shone, RL; Tsai, BS; Widomski, DL; Zemaitis, JM1
Djuric, SW; Fretland, DJ; Miyashiro, JM; Penning, TD; Shone, RL; Widomski, DL1
Anglin, CP; Bremer, M; Djuric, SW; Docter, SH; Fretland, DJ; Isakson, P; Paulson, SK; Penning, TD; Widomski, DL; Yu, S1
Currie, JL; Isakson, PC; Rao, TS; Shaffer, AF1
Anglin, CP; Djuric, SW; Fretland, DJ; Penning, TD; Widomski, DL; Yu, S1

Other Studies

11 other study(ies) available for sc 41930 and mocetinostat

ArticleYear
Granulocyte infiltration in experimental colitis in the rat is interleukin-1 dependent and leukotriene independent.
    Eicosanoids, 1992, Volume: 5, Issue:3-4

    Topics: Analysis of Variance; Animals; Benzopyrans; Chemotaxis, Leukocyte; Colitis; Interleukin-1; Kinetics; Leukotriene B4; Male; Neutrophils; Peroxidase; Quinolines; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid

1992
Induction of colitis in rats by 2-2'-azobis(2-amidinopropane) dihydrochloride.
    Inflammation, 1992, Volume: 16, Issue:1

    Topics: Amidines; Aminosalicylic Acids; Animals; Benzopyrans; Colitis; Inflammation; Intestinal Mucosa; Lipid Peroxidation; Male; Mesalamine; Oxidation-Reduction; Peroxidase; Rats; Rats, Inbred Strains; Sulfasalazine; Sulfhydryl Compounds; Thiobarbiturates

1992
The antiinflammatory agent SC-41930 inhibits granulocyte infiltration of the rodent dermis induced by 6-trans-leukotriene B4.
    Prostaglandins, leukotrienes, and essential fatty acids, 1991, Volume: 44, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Biomarkers; Chemotaxis, Leukocyte; Granulocytes; Guinea Pigs; Injections, Intradermal; Leukotriene B4; Male; Mice; Peroxidase; Skin

1991
Modulation of the chemotactic properties of complement fragments C5a and C3 by the anti-inflammatory agent, SC-41930.
    Agents and actions, 1991, Volume: 34, Issue:1-2

    Topics: Animals; Benzopyrans; Chemotaxis, Leukocyte; Complement C3; Complement C5a; Guinea Pigs; Humans; In Vitro Techniques; Male; Neutrophils; Peroxidase; Recombinant Proteins; Skin

1991
Effect of the leukotriene B4 receptor antagonist SC-41930 on colonic inflammation in rat, guinea pig and rabbit.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2

    Topics: Animals; Benzopyrans; Capillary Permeability; Colitis; Dose-Response Relationship, Drug; Guinea Pigs; Leukotriene B4; Male; Neutrophils; Peroxidase; Rabbits; Rats; Rats, Inbred Strains; Receptors, Immunologic; Receptors, Leukotriene B4

1990
7-[3-(4-acetyl-3-methoxy-2-propylphenoxy)propoxy]-3,4-dihydro-8- propyl-2H-1-benzopyran-2-carboxylic acid: an orally active selective leukotriene B4 receptor antagonist.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

    Topics: Animals; Benzopyrans; Chemical Phenomena; Chemistry; Chemotaxis, Leukocyte; Colitis; Cytoplasmic Granules; Guinea Pigs; Humans; Leukotriene B4; Molecular Structure; Neutrophils; Peroxidase; Receptors, Immunologic; Receptors, Leukotriene B4

1989
The effect of leukotriene-B4 receptor antagonist, SC-41930, on acetic acid-induced colonic inflammation.
    Agents and actions, 1989, Volume: 27, Issue:3-4

    Topics: Acetates; Animals; Benzopyrans; Colitis; Guinea Pigs; Male; Neutrophils; Peroxidase; Receptors, Immunologic; Receptors, Leukotriene B4

1989
SC-41930 inhibits neutrophil infiltration of the cavine dermis induced by 12(R)-hydroxyeicosatetraenoic acid.
    Prostaglandins, leukotrienes, and essential fatty acids, 1989, Volume: 38, Issue:3

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Benzopyrans; Chemotaxis, Leukocyte; Guinea Pigs; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Injections, Intradermal; Male; Neutrophils; Peroxidase; Skin

1989
Antiinflammatory effects of second-generation leukotriene B4 receptor antagonist, SC-53228: impact upon leukotriene B4- and 12(R)-HETE-mediated events.
    Inflammation, 1995, Volume: 19, Issue:2

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Benzopyrans; Biomarkers; Chemotaxis, Leukocyte; Granulocytes; Guinea Pigs; Hydroxyeicosatetraenoic Acids; Injections, Intradermal; Leukotriene B4; Male; Membrane Potentials; Neutrophils; Peroxidase; Receptors, Leukotriene B4; Skin

1995
In vivo characterization of zymosan-induced mouse peritoneal inflammation.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:3

    Topics: Acetophenones; Animals; Arachidonate 5-Lipoxygenase; Benzopyrans; Complement C5a; Leukotriene B4; Male; Mast Cells; Mice; Peritonitis; Peroxidase; Tetrazoles; Zymosan

1994
Leukotriene B4-induced granulocyte trafficking in guinea pig dermis. Effect of second-generation leukotriene B4 receptor antagonists, SC-50605 and SC-51146.
    Inflammation, 1993, Volume: 17, Issue:3

    Topics: Administration, Oral; Animals; Benzamides; Benzopyrans; Chemotaxis, Leukocyte; Granulocytes; Guinea Pigs; Injections, Intradermal; Leukotriene B4; Male; Peroxidase; Receptors, Immunologic; Receptors, Leukotriene B4; Skin; Thiazoles

1993