Compounds > sc 41930
Page last updated: 2024-09-02

sc 41930 and indomethacin

sc 41930 has been researched along with indomethacin in 3 studies

Compound Research Comparison

Studies
(sc 41930)		Trials
(sc 41930)		Recent Studies (post-2010)
(sc 41930)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
540029,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomysc 41930 (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grisham, MB; Keenan, CM; Vaananen, PM; Wallace, JL1
Djuric, SW; Isakson, PC; Rao, TS; Yu, SS1
Bahl, AK; Clayton, NM; Harman, IW; Strong, P; Trevethick, MA1

Other Studies

3 other study(ies) available for sc 41930 and indomethacin

ArticleYear
Pharmacological investigation of the role of leukotrienes in the pathogenesis of experimental NSAID gastropathy.
    Inflammation, 1992, Volume: 16, Issue:3

    Topics: 5-Lipoxygenase-Activating Proteins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Benzopyrans; Carrier Proteins; Free Radical Scavengers; Gastric Mucosa; Hydroxyurea; Indoles; Indomethacin; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Masoprocol; Membrane Proteins; Organic Chemicals; Permeability; Phenylcarbamates; Propionates; Quinolines; Rats; Rats, Inbred Strains; Receptors, Immunologic; Receptors, Leukotriene; Receptors, Leukotriene B4; Single-Blind Method; Stomach Ulcer; Sulfonamides; Tetrazoles; Tosyl Compounds

1992
Phorbol ester-induced dermal inflammation in mice: evaluation of inhibitors of 5-lipoxygenase and antagonists of leukotriene B4 receptor.
    Journal of lipid mediators and cell signalling, 1994, Volume: 10, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Benzamides; Benzopyrans; Dermatitis, Contact; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Receptors, Leukotriene B4; Tetradecanoylphorbol Acetate

1994
Leukotrienes do not contribute to the pathogenesis of indomethacin-induced ulceration of the gastric antrum in the re-fed rat.
    Agents and actions, 1994, Volume: 41, Issue:3-4

    Topics: Administration, Oral; Animals; Benzopyrans; Female; Indazoles; Indoles; Indomethacin; Injections, Subcutaneous; Leukotriene Antagonists; Leukotriene B4; Microscopy, Electron; Pyloric Antrum; Rats; SRS-A; Stomach Ulcer

1994