Page last updated: 2024-09-05

sb 216763 and tws 119

sb 216763 has been researched along with tws 119 in 4 studies

Compound Research Comparison

Studies
(sb 216763)
Trials
(sb 216763)
Recent Studies (post-2010)
(sb 216763)
Studies
(tws 119)
Trials
(tws 119)
Recent Studies (post-2010) (tws 119)
342022516011
342022522021

Protein Interaction Comparison

ProteinTaxonomysb 216763 (IC50)tws 119 (IC50)
Interferon-induced, double-stranded RNA-activated protein kinaseHomo sapiens (human)4
Glycogen synthase kinase-3 betaHomo sapiens (human)0.03
Glycogen synthase kinase-3 betaMus musculus (house mouse)0.03

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Flajolet, M; Greengard, P; Meijer, L1
Dai, WB; Rakesh, KP; Wang, SL; Wu, PY; Xu, M; Zhu, L1
Feng, F; Jiang, X; Liu, X; Sun, H; Wang, Y; Xu, J; Xu, K; Zhou, J1
Edemir, B; Kaiser, M1

Reviews

2 review(s) available for sb 216763 and tws 119

ArticleYear
Pharmacological inhibitors of glycogen synthase kinase 3.
    Trends in pharmacological sciences, 2004, Volume: 25, Issue:9

    Topics: Animals; Cell Differentiation; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Neoplasms; Nervous System Diseases; Parasitic Diseases; Signal Transduction; Stem Cells; Structure-Activity Relationship

2004
Structure-activity relationship (SAR) studies of synthetic glycogen synthase kinase-3β inhibitors: A critical review.
    European journal of medicinal chemistry, 2019, Feb-15, Volume: 164

    Topics: Glycogen Synthase Kinase 3 beta; Humans; Molecular Structure; Protein Binding; Protein Kinase Inhibitors; Structure-Activity Relationship

2019

Other Studies

2 other study(ies) available for sb 216763 and tws 119

ArticleYear
PROTACs suppression of GSK-3β, a crucial kinase in neurodegenerative diseases.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Animals; Enzyme Inhibitors; Glycogen Synthase Kinase 3 beta; HT29 Cells; Humans; Models, Molecular; Neurodegenerative Diseases; PC12 Cells; Proteolysis; Rats; Small Molecule Libraries

2021
Lithium Chloride and GSK3 Inhibition Reduce Aquaporin-2 Expression in Primary Cultured Inner Medullary Collecting Duct Cells Due to Independent Mechanisms.
    Cells, 2020, 04-23, Volume: 9, Issue:4

    Topics: Animals; Aquaporin 2; Aquaporin 3; Aquaporin 4; Cells, Cultured; Chloroquine; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Female; Glycogen Synthase Kinase 3; Indoles; Kidney Tubules, Collecting; Leupeptins; Lithium Chloride; Macrolides; Maleimides; Protein Kinase Inhibitors; Proteolysis; Pyrimidines; Pyrroles; Rats, Wistar; RNA, Messenger

2020