sb 205384 has been researched along with alpha-aminopyridine in 8 studies
| Studies (sb 205384) | Trials (sb 205384) | Recent Studies (post-2010) (sb 205384) | Studies (alpha-aminopyridine) | Trials (alpha-aminopyridine) | Recent Studies (post-2010) (alpha-aminopyridine) |
|---|---|---|---|---|---|
| 26 | 0 | 10 | 5,813 | 460 | 3,246 |
| Protein | Taxonomy | sb 205384 (IC50) | alpha-aminopyridine (IC50) |
|---|---|---|---|
| Botulinum neurotoxin type A | Clostridium botulinum | 1.8 | |
| Nitric oxide synthase, endothelial | Homo sapiens (human) | 2.8 | |
| Nitric oxide synthase, brain | Homo sapiens (human) | 6 | |
| Nitric oxide synthase, brain | Rattus norvegicus (Norway rat) | 9 | |
| Nitric oxide synthase, inducible | Homo sapiens (human) | 1.9 | |
| Phosphatidylinositol 4-kinase alpha | Homo sapiens (human) | 7.1 | |
| Phosphatidylinositol 4-kinase type 2-beta | Homo sapiens (human) | 7.1 | |
| Phosphatidylinositol 4-kinase type 2-alpha | Homo sapiens (human) | 7.1 | |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | 7.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benham, CD; Harries, MH; Meadows, HJ; Thompson, M | 1 |
| Benham, CD; Blackburn, TP; Kumar, CS; Meadows, HJ; Pritchett, DB | 1 |
| Hutcheon, B; Morley, P; Poulter, MO | 1 |
| Burón, E; Martín-López, M; Navarro, JF | 2 |
| Ing, T; Poulter, MO | 1 |
| Long, BC; Miller, BH; Pletcher, MT; Schultz, LE | 1 |
| Fisher, JL; Heidelberg, LS; Warren, JW | 1 |
8 other study(ies) available for sb 205384 and alpha-aminopyridine
| Article | Year |
|---|---|
Effect of SB-205384 on the decay of GABA-activated chloride currents in granule cells cultured from rat cerebellum.
Topics: Aminopyridines; Animals; Cells, Cultured; Cerebellum; Chloride Channels; GABA Modulators; gamma-Aminobutyric Acid; Rats; Receptors, GABA-A; Thiophenes | 1997 |
SB-205384: a GABA(A) receptor modulator with novel mechanism of action that shows subunit selectivity.
Topics: Aminopyridines; Animals; Female; GABA Modulators; Humans; Pyridines; Rats; Receptors, GABA-A; Recombinant Proteins; Thiophenes; Xenopus laevis; Zolpidem | 1998 |
Developmental change in GABAA receptor desensitization kinetics and its role in synapse function in rat cortical neurons.
Topics: Aminopyridines; Animals; Cells, Cultured; Cellular Senescence; Cerebral Cortex; Electric Conductivity; Electrophysiology; Embryo, Mammalian; GABA Modulators; Kinetics; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synapses; Thiophenes | 2000 |
Anxiolytic-like activity of SB-205384 in the elevated plus-maze test in mice.
Topics: Aminopyridines; Animals; Anti-Anxiety Agents; Drug Evaluation, Preclinical; Exploratory Behavior; GABA Agonists; GABA-A Receptor Agonists; Male; Maze Learning; Mice; Random Allocation; Receptors, GABA-A; Stress, Psychological; Thiophenes | 2006 |
Diversity of GABA(A) receptor synaptic currents on individual pyramidal cortical neurons.
Topics: Aminopyridines; Animals; Cells, Cultured; Cerebral Cortex; Female; Furosemide; GABA Agonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Imidazoles; Inhibitory Postsynaptic Potentials; Pregnancy; Pyramidal Cells; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sodium Potassium Chloride Symporter Inhibitors; Synapses; Thiophenes; Zolpidem | 2007 |
Effects of SB-205384, a positive modulator of alpha3-subunit-containing GABA-A receptors, on isolation-induced aggression in male mice.
Topics: Aggression; Aminopyridines; Animals; Behavior, Animal; Male; Mice; Olfaction Disorders; Random Allocation; Receptors, GABA-A; Social Isolation; Thiophenes; Videotape Recording; Zinc Sulfate | 2008 |
Quantitative trait locus analysis identifies Gabra3 as a regulator of behavioral despair in mice.
Topics: Aminopyridines; Animals; Behavior, Animal; Crosses, Genetic; Depression; Genotype; Hindlimb Suspension; Mice; Mice, Inbred C57BL; Mice, Inbred NZB; Quantitative Trait Loci; Receptors, GABA-A; Thiophenes | 2010 |
SB-205384 is a positive allosteric modulator of recombinant GABAA receptors containing rat α3, α5, or α6 subunit subtypes coexpressed with β3 and γ2 subunits.
Topics: Allosteric Regulation; Aminopyridines; Animals; Gene Expression Regulation; HEK293 Cells; Humans; Rats; Receptors, GABA-A; Recombinant Proteins; Thiophenes | 2013 |