sb 204070a has been researched along with tropisetron in 6 studies
| Studies (sb 204070a) | Trials (sb 204070a) | Recent Studies (post-2010) (sb 204070a) | Studies (tropisetron) | Trials (tropisetron) | Recent Studies (post-2010) (tropisetron) |
|---|---|---|---|---|---|
| 45 | 0 | 4 | 944 | 218 | 150 |
| 10 | 0 | 2 | 944 | 218 | 150 |
| Protein | Taxonomy | sb 204070a (IC50) | tropisetron (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 3.1623 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 3.1623 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 3.45 | |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | 1.8 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.488 | |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | 1.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Franks, CM; Hardcastle, J; Hardcastle, PT; Sanger, GJ | 1 |
| Bertrand, PP; Bornstein, JC; Furness, JB; Kunze, WA | 1 |
| Naylor, RJ; Tuladhar, BR; Womack, MD | 1 |
| Ellis, ES; Gaster, LM; Jennings, AJ; Joiner, GF; King, FD; Mulholland, KR; Rahman, SK; Starr, S; Wardle, KA; Wyman, PA | 1 |
| Bender, E; Gommeren, W; Jurzak, M; Leysen, J; Luyten, W; Van den Wyngaert, I; Verhasselt, P | 1 |
| Boulouard, M; Bureau, R; Butt-Gueulle, S; Dauphin, F; Daveu, C; Duchatelle, P; Dumuis, A; Lelong-Boulouard, V; Lemaître, S; Lepailleur, A; Lezoualc'h, F; Pfeiffer, B; Rault, S | 1 |
6 other study(ies) available for sb 204070a and tropisetron
| Article | Year |
|---|---|
Do 5-HT4 receptors mediate the intestinal secretory response to 5-HT in rat in-vivo?
Topics: 4-Aminobenzoic Acid; 5-Methoxytryptamine; Animals; Benzamides; Blood Pressure; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Colon; Dioxanes; Dose-Response Relationship, Drug; Heart Rate; Ileum; Indoles; Intestinal Mucosa; Jejunum; Male; para-Aminobenzoates; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron | 1995 |
The terminals of myenteric intrinsic primary afferent neurons of the guinea-pig ileum are excited by 5-hydroxytryptamine acting at 5-hydroxytryptamine-3 receptors.
Topics: 5-Methoxytryptamine; Action Potentials; Animals; Dioxanes; Granisetron; Guinea Pigs; Ileum; Indoles; Myenteric Plexus; Neurons, Afferent; Piperidines; Presynaptic Terminals; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Signal Transduction; Tropisetron | 2000 |
Pharmacological characterization of the 5-HT receptor-mediated contraction in the mouse isolated ileum.
Topics: Animals; Atropine; Dioxanes; Dose-Response Relationship, Drug; Female; Granisetron; Ileum; In Vitro Techniques; Indoles; Ketanserin; Male; Mice; Muscle Contraction; Ondansetron; Piperidines; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin; Tropanes; Tropisetron | 2000 |
(1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-1,4-benzodioxane-5-carboxylate hydrochloride: a highly potent and selective 5-HT4 receptor antagonist derived from metoclopramide.
Topics: Animals; Dioxanes; Guinea Pigs; Metoclopramide; Muscle Contraction; Piperidines; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship | 1993 |
Cloning and expression of a human serotonin 5-HT4 receptor cDNA.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Brain; Cell Membrane; Cloning, Molecular; COS Cells; Cytosine; DNA Primers; Frameshift Mutation; Guinea Pigs; Humans; Indoles; Kinetics; Molecular Sequence Data; Open Reading Frames; Polymerase Chain Reaction; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Sulfonamides; Swine; Transfection | 1997 |
Novel antagonists of serotonin-4 receptors: synthesis and biological evaluation of pyrrolothienopyrazines.
Topics: Animals; Chlorocebus aethiops; COS Cells; Humans; Indoles; Models, Molecular; Molecular Structure; Pyrazines; Radioligand Assay; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Sulfonamides | 2009 |