sb 204070a has been researched along with piboserod in 4 studies
| Studies (sb 204070a) | Trials (sb 204070a) | Recent Studies (post-2010) (sb 204070a) | Studies (piboserod) | Trials (piboserod) | Recent Studies (post-2010) (piboserod) |
|---|---|---|---|---|---|
| 45 | 0 | 4 | 119 | 5 | 53 |
| 10 | 0 | 2 | 119 | 5 | 53 |
| Protein | Taxonomy | sb 204070a (IC50) | piboserod (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Homo sapiens (human) | 0.0006 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bingham, S; Ellis, ES; Gaster, LM; Joiner, GF; King, FD; Sanger, GJ; Sutton, JM; Wardle, KA; Wyman, PA | 1 |
| Karaki, S; Kuwahara, A; Mitsui, R; Ono, S | 1 |
| Amano, T; Ariga, H; Ishida, T; Kimura, T; Matsueda, K; Tajiri, H; Torii, A; Uehara, H; Yamato, S | 1 |
| Boulouard, M; Bureau, R; Butt-Gueulle, S; Dauphin, F; Daveu, C; Duchatelle, P; Dumuis, A; Lelong-Boulouard, V; Lemaître, S; Lepailleur, A; Lezoualc'h, F; Pfeiffer, B; Rault, S | 1 |
4 other study(ies) available for sb 204070a and piboserod
| Article | Year |
|---|---|
N-[(1-butyl-4-piperidinyl)methyl]-3,4dihydro-2H-[1,3]oxazino[3,2- a]indole10-carboxamide hydrochloride: the first potent and selective 5-HT4 receptor antagonist amide with oral activity.
Topics: Administration, Oral; Animals; Dioxanes; Dogs; Guinea Pigs; Indoles; Muscle Contraction; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides | 1995 |
Muscarinic and 5-HT4 receptors participate in the regulation of the frequency of spontaneous contractions of the longitudinal muscle in rat distal colon.
Topics: Animals; Atropine; Colon; Dioxanes; Gastrointestinal Motility; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Organ Culture Techniques; Piperidines; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists | 2005 |
Urocortin I is present in the enteric nervous system and exerts an excitatory effect via cholinergic and serotonergic pathways in the rat colon.
Topics: Animals; Atropine; Colon; Corticotropin-Releasing Hormone; Dioxanes; Electric Stimulation; Enteric Nervous System; Gastrointestinal Motility; Hexamethonium; Immunohistochemistry; Male; NG-Nitroarginine Methyl Ester; Ondansetron; Peptide Fragments; Piperidines; Pyrimidines; Pyrroles; Rats; Receptors, Corticotropin-Releasing Hormone; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Tetrodotoxin; Urocortins | 2007 |
Novel antagonists of serotonin-4 receptors: synthesis and biological evaluation of pyrrolothienopyrazines.
Topics: Animals; Chlorocebus aethiops; COS Cells; Humans; Indoles; Models, Molecular; Molecular Structure; Pyrazines; Radioligand Assay; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Sulfonamides | 2009 |