Compounds > sb 204070a

Page last updated: 2024-09-03

sb 204070a and gr 113808

sb 204070a has been researched along with gr 113808 in 12 studies

Compound Research Comparison

Studies (sb 204070a)	Trials (sb 204070a)	Recent Studies (post-2010) (sb 204070a)	Studies (gr 113808)	Trials (gr 113808)	Recent Studies (post-2010) (gr 113808)
45	0	4	165	1	35
10	0	2	165	1	35

Protein Interaction Comparison

Protein	Taxonomy	sb 204070a (IC50)	gr 113808 (IC50)
5-hydroxytryptamine receptor 4	Homo sapiens (human)		0.0002

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (41.67)	18.2507
2000's	7 (58.33)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Bingham, S; Ellis, ES; Gaster, LM; Joiner, GF; King, FD; Sanger, GJ; Sutton, JM; Wardle, KA; Wyman, PA	1
Bonhaus, DW; Clark, RD; Eglen, RM; Hegde, SS; Johnson, LG; Leung, E	1
Eglen, RM; Hedge, SS; Loeb, M; Moy, TM; Perry, MR	1
Fernández, AG; Palacios, JM; Silvestre, JS	1
Amor, AL; Bandeira, IP; Carvalho, FL; Castro, L; De Castro-E-Silva, E; Ferreira, MG; Fregoneze, JB; Lima, AK; Macêdo, DF; Maldonado, I; Oliveira, IR; Rocha, MA; Santamaria, GF; Souza, FS	1
Bosmans, JP; Briejer, MR; Heylen, L; Jurzak, M; Leysen, JE; Prins, NH; Schuurkes, JA; Van Daele, P	1
Bender, E; Gommeren, W; Jurzak, M; Leysen, J; Luyten, W; Van den Wyngaert, I; Verhasselt, P	1
Bender, E; Gommeren, W; Jurzak, M; Leysen, J; Luyten, W; Pindon, A; van Oers, I; Verhasselt, P; Zhang, YB	1
Berque-Bestel, I; Fischmeister, R; Langlois, M; Lezoualc'h, F; Mialet, J; Sicsic, S	1
Boulouard, M; Bureau, R; Butt-Gueulle, S; Dauphin, F; Daveu, C; Duchatelle, P; Dumuis, A; Lelong-Boulouard, V; Lemaître, S; Lepailleur, A; Lezoualc'h, F; Pfeiffer, B; Rault, S	1

Other Studies

12 other study(ies) available for sb 204070a and gr 113808

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
N-[(1-butyl-4-piperidinyl)methyl]-3,4dihydro-2H-[1,3]oxazino[3,2- a]indole10-carboxamide hydrochloride: the first potent and selective 5-HT4 receptor antagonist amide with oral activity. Journal of medicinal chemistry, 1995, Nov-24, Volume: 38, Issue:24 Topics: Administration, Oral; Animals; Dioxanes; Dogs; Guinea Pigs; Indoles; Muscle Contraction; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides	1995
RS 39604: a potent, selective and orally active 5-HT4 receptor antagonist. British journal of pharmacology, 1995, Volume: 115, Issue:6 Topics: Administration, Oral; Animals; Colon; Dioxanes; Dose-Response Relationship, Drug; Esophagus; Guinea Pigs; Indoles; Male; Mice; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Sulfonamides; Time Factors	1995
Evidence for the involvement of 5-hydroxytryptamine 4 receptors in 5-hydroxytryptophan-induced diarrhea in mice. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:2 Topics: 5-Hydroxytryptophan; Animals; Atropine; Benserazide; Benzimidazoles; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Diarrhea; Dioxanes; Indoles; Male; Mice; Parasympathetic Nervous System; Piperidines; Receptors, Serotonin; Sulfonamides	1994
Effects of 5-HT4 receptor antagonists on rat behaviour in the elevated plus-maze test. European journal of pharmacology, 1996, Aug-15, Volume: 309, Issue:3 Topics: Animals; Behavior, Animal; Diazepam; Dioxanes; Dose-Response Relationship, Drug; Granisetron; Indoles; Male; Maze Learning; Piperidines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Sulfonamides	1996
Central 5-HT(4) receptors and drinking behavior. Pharmacology, biochemistry, and behavior, 2000, Volume: 66, Issue:2 Topics: Animals; Dioxanes; Drinking; Drinking Behavior; Indoles; Injections, Intraventricular; Male; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Sulfonamides; Thirst; Water Deprivation	2000
The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound. European journal of pharmacology, 2001, Jun-29, Volume: 423, Issue:1 Topics: Acetylcholine; Animals; Benzofurans; Binding, Competitive; Carbachol; Cell Line; CHO Cells; Colon; Cricetinae; Dioxanes; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Esophagus; Female; Gallbladder; Gastrointestinal Agents; Granisetron; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Indoles; Indomethacin; Male; Motilin; Muscle Contraction; Piperidines; Rabbits; Rats; Rats, Wistar; Receptors, Cholecystokinin; Receptors, Dopamine D2; Receptors, Dopamine D4; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sincalide; Stomach; Sulfonamides; Vasodilator Agents	2001
Cloning and expression of a human serotonin 5-HT4 receptor cDNA. Journal of neurochemistry, 1997, Volume: 69, Issue:5 Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Brain; Cell Membrane; Cloning, Molecular; COS Cells; Cytosine; DNA Primers; Frameshift Mutation; Guinea Pigs; Humans; Indoles; Kinetics; Molecular Sequence Data; Open Reading Frames; Polymerase Chain Reaction; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Sulfonamides; Swine; Transfection	1997
Structure of the human serotonin 5-HT4 receptor gene and cloning of a novel 5-HT4 splice variant. Journal of neurochemistry, 2000, Volume: 74, Issue:2 Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; COS Cells; DNA, Recombinant; Genetic Variation; Humans; Molecular Sequence Data; Protein Isoforms; Receptors, Serotonin; RNA, Messenger; Tissue Distribution	2000
Pharmacological characterization of the human 5-HT(4(d)) receptor splice variant stably expressed in Chinese hamster ovary cells. British journal of pharmacology, 2000, Volume: 131, Issue:4 Topics: Animals; CHO Cells; Cricetinae; Cyclic AMP; Humans; Indoles; Protein Isoforms; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Structure-Activity Relationship; Sulfonamides	2000
Novel antagonists of serotonin-4 receptors: synthesis and biological evaluation of pyrrolothienopyrazines. Bioorganic & medicinal chemistry, 2009, Mar-15, Volume: 17, Issue:6 Topics: Animals; Chlorocebus aethiops; COS Cells; Humans; Indoles; Models, Molecular; Molecular Structure; Pyrazines; Radioligand Assay; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Sulfonamides	2009