Page last updated: 2024-09-03

sb 204070a and cisapride

sb 204070a has been researched along with cisapride in 5 studies

Compound Research Comparison

Studies
(sb 204070a)
Trials
(sb 204070a)
Recent Studies (post-2010)
(sb 204070a)
Studies
(cisapride)
Trials
(cisapride)
Recent Studies (post-2010) (cisapride)
45041,554390110
10021,554390110

Protein Interaction Comparison

ProteinTaxonomysb 204070a (IC50)cisapride (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.767
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)3.37
Cytochrome P450 3A4Homo sapiens (human)0.3
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0098
Alpha-2A adrenergic receptorHomo sapiens (human)3.5923
Cytochrome P450 2D6Homo sapiens (human)0.07
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.1701
D(2) dopamine receptorHomo sapiens (human)0.35
Dipeptidyl peptidase 4Rattus norvegicus (Norway rat)2.69
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0098
Insulin receptor Rattus norvegicus (Norway rat)3.37
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)2.29
Alpha-2B adrenergic receptorHomo sapiens (human)3.3827
Alpha-2C adrenergic receptorHomo sapiens (human)3.26
DRattus norvegicus (Norway rat)0.0065
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)3.6495
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.0065
D(1A) dopamine receptorHomo sapiens (human)1.7
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.0065
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.0065
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)2.29
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.0065
Alpha-1D adrenergic receptorHomo sapiens (human)0.083
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0054
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.2597
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)3.6495
5-hydroxytryptamine receptor 1DRattus norvegicus (Norway rat)4.47
5-hydroxytryptamine receptor 1FRattus norvegicus (Norway rat)4.47
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.0098
Sodium-dependent serotonin transporterHomo sapiens (human)0.384
Alpha-1A adrenergic receptorHomo sapiens (human)0.03
Prostaglandin G/H synthase 2Homo sapiens (human)3.37
Alpha-1B adrenergic receptorHomo sapiens (human)0.03
D(3) dopamine receptorHomo sapiens (human)0.144
5-hydroxytryptamine receptor 3ARattus norvegicus (Norway rat)0.9
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.0407
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)2.29
D(2) dopamine receptorRattus norvegicus (Norway rat)0.535
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.2536
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)0.1701
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.994
5-hydroxytryptamine receptor 3BRattus norvegicus (Norway rat)0.9

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Franks, CM; Hardcastle, J; Hardcastle, PT; Sanger, GJ1
Bender, E; Gommeren, W; Jurzak, M; Leysen, J; Luyten, W; Van den Wyngaert, I; Verhasselt, P1
Bender, E; Gommeren, W; Jurzak, M; Leysen, J; Luyten, W; Pindon, A; van Oers, I; Verhasselt, P; Zhang, YB1
Berque-Bestel, I; Dahmoune, Y; Donzeau-Gouge, P; Eftekhari, P; Fischmeister, R; Gastineau, M; Giner, M; Hoebeke, J; Langlois, M; Lezoualc'h, F; Mialet, J; Sicsic, S1
Berque-Bestel, I; Fischmeister, R; Langlois, M; Lezoualc'h, F; Mialet, J; Sicsic, S1

Other Studies

5 other study(ies) available for sb 204070a and cisapride

ArticleYear
Do 5-HT4 receptors mediate the intestinal secretory response to 5-HT in rat in-vivo?
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:3

    Topics: 4-Aminobenzoic Acid; 5-Methoxytryptamine; Animals; Benzamides; Blood Pressure; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Colon; Dioxanes; Dose-Response Relationship, Drug; Heart Rate; Ileum; Indoles; Intestinal Mucosa; Jejunum; Male; para-Aminobenzoates; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron

1995
Cloning and expression of a human serotonin 5-HT4 receptor cDNA.
    Journal of neurochemistry, 1997, Volume: 69, Issue:5

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Brain; Cell Membrane; Cloning, Molecular; COS Cells; Cytosine; DNA Primers; Frameshift Mutation; Guinea Pigs; Humans; Indoles; Kinetics; Molecular Sequence Data; Open Reading Frames; Polymerase Chain Reaction; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Sulfonamides; Swine; Transfection

1997
Structure of the human serotonin 5-HT4 receptor gene and cloning of a novel 5-HT4 splice variant.
    Journal of neurochemistry, 2000, Volume: 74, Issue:2

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; COS Cells; DNA, Recombinant; Genetic Variation; Humans; Molecular Sequence Data; Protein Isoforms; Receptors, Serotonin; RNA, Messenger; Tissue Distribution

2000
Isolation of the serotoninergic 5-HT4(e) receptor from human heart and comparative analysis of its pharmacological profile in C6-glial and CHO cell lines.
    British journal of pharmacology, 2000, Volume: 129, Issue:4

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Antibody Specificity; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Glioma; Heart Atria; Humans; Molecular Sequence Data; Myocardium; Organ Specificity; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Reverse Transcriptase Polymerase Chain Reaction; Serotonin Antagonists; Serotonin Receptor Agonists

2000
Pharmacological characterization of the human 5-HT(4(d)) receptor splice variant stably expressed in Chinese hamster ovary cells.
    British journal of pharmacology, 2000, Volume: 131, Issue:4

    Topics: Animals; CHO Cells; Cricetinae; Cyclic AMP; Humans; Indoles; Protein Isoforms; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Structure-Activity Relationship; Sulfonamides

2000