Compounds > sb 203580
Page last updated: 2024-09-05

sb 203580 and verapamil

sb 203580 has been researched along with verapamil in 4 studies

Compound Research Comparison

Studies
(sb 203580)		Trials
(sb 203580)		Recent Studies (post-2010)
(sb 203580)		Studies
(verapamil)		Trials
(verapamil)		Recent Studies (post-2010) (verapamil)
3,48941,13717,6211,5272,067

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)verapamil (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)6.8
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.297
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
ATP-dependent translocase ABCB1Homo sapiens (human)2.2346
Cytochrome P450 3A4Homo sapiens (human)3.8008
Alpha-2A adrenergic receptorHomo sapiens (human)0.579
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)3.02
ATP-dependent translocase ABCB1Mus musculus (house mouse)10
Catechol O-methyltransferaseHomo sapiens (human)0.2
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)8
Histamine H2 receptorHomo sapiens (human)2.59
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.442
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.297
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)3.02
Sodium-dependent serotonin transporterHomo sapiens (human)0.24
Multidrug resistance-associated protein 1 Homo sapiens (human)5.598
D(3) dopamine receptorHomo sapiens (human)0.186
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.165
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)6.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.2
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.3945
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.2
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.175
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.1934

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Hori, M; Karaki, H; Ozaki, H; Tasaki, K; Wakabayashi, I2
Campos-Toimil, M; Cuíñas, A; Elíes, J; Orallo, F1

Other Studies

4 other study(ies) available for sb 203580 and verapamil

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Difference in signal transduction mechanisms involved in 5-hydroxytryptamine- and U46619-induced vasoconstrictions.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2003, Volume: 39, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Calcium; Enzyme Inhibitors; Extracellular Fluid; Genistein; Imidazoles; Male; Naphthalenes; Pyridines; Rats; Rats, Wistar; Serotonin; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Verapamil

2003
Mechanism of human urotensin II-induced contraction in rat aorta.
    Journal of pharmacological sciences, 2004, Volume: 94, Issue:4

    Topics: Androstadienes; Animals; Aorta, Thoracic; Butadienes; Calcium; Carbazoles; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Indoles; Lanthanum; Male; Maleimides; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle Contraction; Myosin Light Chains; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Potassium Chloride; Protein Kinase C; Pyridines; Rats; Rats, Wistar; Thapsigargin; Urotensins; Verapamil; Wortmannin

2004
Cyclic AMP relaxation of rat aortic smooth muscle is mediated in part by decrease of depletion of intracellular Ca(2+) stores and inhibition of capacitative calcium entry.
    Vascular pharmacology, 2013, Volume: 58, Issue:1-2

    Topics: Animals; Aorta, Thoracic; Calcium; Colforsin; Cyclic AMP; Imidazoles; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nifedipine; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Phosphodiesterase 4 Inhibitors; Pyridines; Rats; Rats, Inbred WKY; Rolipram; Vasodilation; Vasodilator Agents; Verapamil

2013