sb 203580 has been researched along with ucn 1028 c in 25 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (ucn 1028 c) | Trials (ucn 1028 c) | Recent Studies (post-2010) (ucn 1028 c) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 984 | 2 | 60 |
| Protein | Taxonomy | sb 203580 (IC50) | ucn 1028 c (IC50) |
|---|---|---|---|
| Dipeptidyl peptidase 4 | Rattus norvegicus (Norway rat) | 1.1 | |
| Catenin beta-1 | Homo sapiens (human) | 10 | |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | 1.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (12.00) | 18.2507 |
| 2000's | 19 (76.00) | 29.6817 |
| 2010's | 3 (12.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kato, T; Sasaki, MS; Shimizu, T; Tachibana, A | 1 |
| Kozawa, O; Miwa, M; Tokuda, H; Uematsu, T | 1 |
| Kato, K; Kawamura, H; Kozawa, O; Matsui, N; Matsuno, H; Niwa, M; Otsuka, T; Uematsu, T | 1 |
| Gnudi, L; Gruden, G; Hayward, A; Maestrini, S; Thomas, S; Viberti, GC; Zonca, S | 1 |
| Arndt, H; Palitzsch, KD; Schäffler, A; Schölmerich, J | 1 |
| Hatakeyama, D; Kawamura, H; Kozawa, O; Matsuno, H; Uematsu, T | 1 |
| Davis, HW; Zhao, Y | 1 |
| Chen, CC; Chen, JJ; Chou, CY | 1 |
| Delannoy, P; Lemonnier, J; Lomri, A; Marie, PJ | 1 |
| Choi, MR; Suh, HW; Won, JS | 1 |
| Hatakeyama, D; Ito, H; Kato, K; Kozawa, O; Matsui, N; Matsuno, H; Niwa, M; Otsuka, T; Uematsu, T | 1 |
| Kato, K; Kozawa, O; Matsuno, H; Niwa, M; Tokuda, H; Uematsu, T | 1 |
| Hsu, HY; Wen, MH | 1 |
| Dai, J; Remick, DG; Wang, X; Zeng, X | 1 |
| Chain, BM; Cho, JY; Katz, DR | 1 |
| Agrawal, DK; DelCore, MG; Hunter, WJ; Krueger, KD | 1 |
| Hori, M; Karaki, H; Ozaki, H; Tasaki, K; Wakabayashi, I | 1 |
| Hosoe, M; Katoh, T; Komurasaki, T; Mikami, Y; Miyahara, T; Nemoto, N; Sakuma, T; Takayama, K; Uchida, S; Watanabe, M | 1 |
| Iijima, R; Ishida, A; Kobayashi, A; Maeda, M | 1 |
| Cao, J; Cetrulo, CL; Kandere-Grzybowska, K; Kempuraj, D; Theoharides, TC | 1 |
| Gu, R; Jin, Y; Kong, S; Li, W; Wang, L; Wang, WH; Yang, B; Yang, L; Zhai, Y; Zhang, C; Zhang, Y | 1 |
| Asano, S; Itoh, M; Nishiwaki-Yasuda, K; Sekiguchi, S; Shibata, M; Suzuki, A | 1 |
| Arda, O; Basar, M; Buchwalder, LF; Godlewski, K; Huang, SJ; Kayisli, UA; Kocamaz, E; Lockwood, CJ; Murk, W; Schatz, F; Yen, CF | 1 |
| Radhika, A; Sudhakaran, PR | 1 |
| Choi, S; Jiao, HY; Jun, JY; Kim, MW; Kim, SW; Lee, MJ; Na, J; Park, CG; Park, IK; Shin, DH; So, I | 1 |
25 other study(ies) available for sb 203580 and ucn 1028 c
| Article | Year |
|---|---|
Coordinated regulation of radioadaptive response by protein kinase C and p38 mitogen-activated protein kinase.
Topics: Adaptation, Biological; Animals; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromosome Aberrations; Dose-Response Relationship, Radiation; Enzyme Activation; Imidazoles; Isoenzymes; Mice; Mitogen-Activated Protein Kinases; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phospholipase C delta; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Pyridines; Radiation Tolerance; Signal Transduction; Type C Phospholipases; Ultraviolet Rays; X-Rays | 1999 |
Mitogen-activated protein (MAP) kinases are involved in interleukin-1 (IL-1)-induced IL-6 synthesis in osteoblasts: modulation not of p38 MAP kinase, but of p42/p44 MAP kinase by IL-1-activated protein kinase C.
Topics: Animals; Animals, Newborn; Bridged-Ring Compounds; Cell Line; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Imidazoles; Interleukin-1; Interleukin-6; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; Norbornanes; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Pyridines; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones | 1999 |
Endothelin-1 stimulates heat shock protein 27 induction in osteoblasts: involvement of p38 MAP kinase.
Topics: Animals; Antihypertensive Agents; Blotting, Northern; Carcinogens; Cells, Cultured; Endothelin-1; Enzyme Inhibitors; Estrenes; Flavonoids; Gene Expression Regulation, Enzymologic; Genistein; Heat-Shock Proteins; Imidazoles; Mice; Mitogen-Activated Protein Kinases; Naphthalenes; Oligopeptides; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Peptides, Cyclic; Phorbol Esters; Phosphodiesterase Inhibitors; Phosphorylation; Piperidines; Propranolol; Protein Kinase C; Pyridines; Pyrrolidinones; RNA, Messenger; Skull; Staurosporine | 1999 |
Mechanical stretch-induced fibronectin and transforming growth factor-beta1 production in human mesangial cells is p38 mitogen-activated protein kinase-dependent.
Topics: Biomechanical Phenomena; Enzyme Activation; Enzyme Inhibitors; Fibronectins; Glomerular Mesangium; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Pyridines; Transforming Growth Factor beta | 2000 |
Amelioration of hyperglycemic and hyperosmotic induced vascular dysfunction by in vivo inhibition of protein kinase C and p38 MAP kinase pathway in the rat mesenteric microcirculation.
Topics: Animals; Capillaries; Cell Adhesion; Diabetic Angiopathies; Diuretics, Osmotic; Enzyme Inhibitors; Glucose; Hyperglycemia; Imidazoles; Leukocytes; Male; Mannitol; MAP Kinase Signaling System; Microcirculation; Mitogen-Activated Protein Kinases; Naphthalenes; Osmotic Pressure; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; Water-Electrolyte Balance | 2000 |
Endothelin-1 induces vascular endothelial growth factor synthesis in osteoblasts: involvement of p38 mitogen-activated protein kinase.
Topics: Animals; Endothelial Growth Factors; Endothelin-1; Enzyme Inhibitors; Estrenes; Flavonoids; Gene Expression Regulation; Imidazoles; Lymphokines; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Naphthalenes; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phorbol Esters; Protein Kinase C; Pyridines; Pyrrolidinones; Receptor, Endothelin A; Receptors, Endothelin; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
Endotoxin causes phosphorylation of MARCKS in pulmonary vascular endothelial cells.
Topics: Animals; Cattle; Cell Membrane; Cells, Cultured; Cytosol; Endothelium, Vascular; Enzyme Inhibitors; Genistein; Gram-Negative Bacterial Infections; Imidazoles; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinases; Myosin Light Chains; Myristoylated Alanine-Rich C Kinase Substrate; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Transport; Protein-Tyrosine Kinases; Proteins; Pulmonary Artery; Pyridines; Respiratory Distress Syndrome; Tetradecanoylphorbol Acetate; Thrombin | 2000 |
Protein kinase calpha but not p44/42 mitogen-activated protein kinase, p38, or c-Jun NH(2)-terminal kinase is required for intercellular adhesion molecule-1 expression mediated by interleukin-1beta: involvement of sequential activation of tyrosine kinase,
Topics: Bridged-Ring Compounds; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Fluorescent Antibody Technique; Gene Expression; Humans; I-kappa B Kinase; Imidazoles; Indoles; Intercellular Adhesion Molecule-1; Interleukin-1; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Naphthalenes; NF-kappaB-Inducing Kinase; Norbornanes; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Kinase C-alpha; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; Staurosporine; Thiocarbamates; Thiones; Tyrphostins | 2000 |
Increased expression of protein kinase Calpha, interleukin-1alpha, and RhoA guanosine 5'-triphosphatase in osteoblasts expressing the Ser252Trp fibroblast growth factor 2 receptor Apert mutation: identification by analysis of complementary DNA microarray.
Topics: Acrocephalosyndactylia; Amino Acid Substitution; Cell Line, Transformed; DNA, Complementary; Enzyme Induction; Enzyme Inhibitors; Fetus; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Interleukin-1; Isoenzymes; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Naphthalenes; Oligonucleotide Array Sequence Analysis; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Point Mutation; Protein Kinase C; Protein Kinase C-alpha; Protein Serine-Threonine Kinases; Pyridines; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Fibroblast Growth Factor; rhoA GTP-Binding Protein; Skull; Subtraction Technique | 2001 |
Stimulation of astrocyte-enriched culture with C2 ceramide increases proenkephalin mRNA: involvement of cAMP-response element binding protein and mitogen activated protein kinases.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Astrocytes; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Enkephalins; Enzyme Inhibitors; Flavonoids; Gene Expression; Imidazoles; Isoquinolines; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Protein Precursors; Protein Synthesis Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sphingosine; Stimulation, Chemical; Sulfonamides; Transcription Factor AP-1 | 2001 |
Mechanism of prostaglandin D(2)-stimulated heat shock protein 27 induction in osteoblasts.
Topics: Animals; Cell Line; Enzyme Inhibitors; Flavonoids; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Imidazoles; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prostaglandin D2; Pyridines; RNA, Messenger; Staurosporine | 2001 |
Mechanism of prostaglandin E2-stimulated heat shock protein 27 induction in osteoblast-like MC3T3-E1 cells.
Topics: Analysis of Variance; Animals; Butadienes; Calcium; Calcium Channel Blockers; Cell Line; Chelating Agents; Dinoprostone; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Gallic Acid; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Imidazoles; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Molecular Chaperones; Naphthalenes; Neoplasm Proteins; Nitriles; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Pyridines; Pyrrolidinones; Staurosporine; Stimulation, Chemical; Time Factors; Type C Phospholipases | 2002 |
Lipopolysaccharide-mediated reactive oxygen species and signal transduction in the regulation of interleukin-1 gene expression.
Topics: Animals; Carrier Proteins; Cell Line; Chromones; Curcumin; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flavonoids; Gene Expression Regulation; Genes, Dominant; Imidazoles; Interleukin-1; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Biological; Morpholines; Naphthalenes; Oxygen; p38 Mitogen-Activated Protein Kinases; Protein Binding; Pyridines; rac1 GTP-Binding Protein; Reactive Oxygen Species; Signal Transduction; Time Factors; Transfection | 2002 |
Homocysteine mediated expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human monocytes.
Topics: Antioxidants; Cells, Cultured; Chemokine CCL2; Chromans; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Genistein; Homocysteine; Humans; Imidazoles; Indoles; Interleukin-8; Monocytes; Naphthalenes; Onium Compounds; Pyridines; Pyrrolidines; Reactive Oxygen Species; RNA, Messenger; Sulfonamides; Thiazoles; Thiazolidinediones; Thiocarbamates; Time Factors; Troglitazone; Tyrphostins | 2003 |
Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation.
Topics: Acetophenones; Adenosine Triphosphate; Benzopyrans; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; CD18 Antigens; Cell Aggregation; Cycloheximide; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Humans; Imidazoles; Indoles; Integrin beta1; Isoenzymes; Maleimides; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Phosphotransferases; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Staurosporine; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; U937 Cells | 2003 |
Calphostin C as a rapid and strong inducer of apoptosis in human coronary artery smooth muscle cells.
Topics: Androstadienes; Animals; Apoptosis; Cells, Cultured; Chromones; Coronary Vessels; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Flavonoids; Humans; Imidazoles; In Situ Nick-End Labeling; Insulin-Like Growth Factor I; Microscopy, Electron, Scanning; Microscopy, Video; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Smooth, Vascular; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Signal Transduction; Staurosporine; Time Factors; Wortmannin | 2003 |
Difference in signal transduction mechanisms involved in 5-hydroxytryptamine- and U46619-induced vasoconstrictions.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Calcium; Enzyme Inhibitors; Extracellular Fluid; Genistein; Imidazoles; Male; Naphthalenes; Pyridines; Rats; Rats, Wistar; Serotonin; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Verapamil | 2003 |
Involvement of mitogen-activated protein kinases and protein kinase C in cadmium-induced prostaglandin E2 production in primary mouse osteoblastic cells.
Topics: Animals; Blotting, Western; Cadmium; Dinoprostone; Enzyme Inhibitors; Female; Flavonoids; Imidazoles; Kinetics; Mice; Mitogen-Activated Protein Kinases; Naphthalenes; Osteoblasts; Phospholipases A; Phospholipases A2; Phosphorylation; Pregnancy; Protein Kinase C; Pyridines; Signal Transduction | 2004 |
Characterization of cAMP-dependent proteolysis of GATA-6.
Topics: Animals; Base Sequence; Benzylamines; Binding Sites; Bucladesine; Carbazoles; Cell Nucleus; CHO Cells; Cricetinae; Cyclic AMP; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; GATA6 Transcription Factor; Humans; Imidazoles; Indole Alkaloids; Isoquinolines; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Molecular Sequence Data; Mutation; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plasmids; Prostaglandin D2; Proteasome Endopeptidase Complex; Protein Binding; Pyridines; src-Family Kinases; Sulfonamides; Transcription Factors | 2005 |
Regulation of IL-1-induced selective IL-6 release from human mast cells and inhibition by quercetin.
Topics: Carbazoles; Cell Line, Tumor; Cells, Cultured; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Humans; Imidazoles; Indoles; Interleukin-1; Interleukin-6; Isoenzymes; Mast Cells; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Quercetin | 2006 |
PGE2 inhibits basolateral 50 pS potassium channels in the thick ascending limb of the rat kidney.
Topics: Animals; Cells, Cultured; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Female; Flavonoids; Imidazoles; Kidney; Kidney Cortex; Male; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Phosphorylation; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Specific Pathogen-Free Organisms | 2008 |
Effects of prostaglandin D2 on Na-dependent phosphate transport activity and its intracellular signaling mechanism in osteoblast-like cells.
Topics: 3T3 Cells; Animals; Anthracenes; Butadienes; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Imidazoles; Mice; Morpholines; Naphthalenes; Nitriles; Osteoblasts; Phosphates; Prostaglandin D2; Pyridines; Signal Transduction; Sirolimus; Sodium | 2009 |
Preeclampsia-related increase of interleukin-11 expression in human decidual cells.
Topics: Adult; Decidua; Estradiol; Female; Humans; Imidazoles; Immunohistochemistry; Interleukin-11; Interleukin-1beta; Naphthalenes; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pre-Eclampsia; Pregnancy; Protein Kinase C; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Statistics, Nonparametric; Tumor Necrosis Factor-alpha | 2010 |
Upregulation of macrophage-specific functions by oxidized LDL: lysosomal degradation-dependent and -independent pathways.
Topics: Acetylcysteine; Cell Differentiation; Cells, Cultured; Chloroquine; Chromones; Copper Sulfate; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Gene Expression; Humans; Imidazoles; Leukocytes, Mononuclear; Lipoproteins, LDL; Lysosomes; Macrophages; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Morpholines; Naphthalenes; NF-kappa B; Oxidation-Reduction; PPAR gamma; Proteolysis; Pyridines; Signal Transduction; Transcription Factor AP-1; Transcriptional Activation; Up-Regulation | 2013 |
Regulatory Roles of Endogenous Mitogen-Activated Protein Kinases and Tyrosine Kinases in the Pacemaker Activity of Colonic Interstitial Cells of Cajal.
Topics: Animals; Anthracenes; Benzophenanthridines; Cells, Cultured; Chromones; Colon; Flavonoids; Genistein; Imidazoles; Interstitial Cells of Cajal; Intestine, Small; Membrane Potentials; Mice; Mitogen-Activated Protein Kinases; Morpholines; Naphthalenes; Protein-Tyrosine Kinases; Pyridines; Rifabutin | 2015 |