sb 203580 has been researched along with tretinoin in 15 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (tretinoin) | Trials (tretinoin) | Recent Studies (post-2010) (tretinoin) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 23,654 | 1,083 | 6,085 |
| Protein | Taxonomy | sb 203580 (IC50) | tretinoin (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.18 | |
| Adenosine receptor A3 | Homo sapiens (human) | 5.275 | |
| Retinoic acid receptor alpha | Homo sapiens (human) | 2.2542 | |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 5.3 | |
| Retinoic acid receptor beta | Homo sapiens (human) | 0.7537 | |
| Retinoic acid receptor alpha | Mus musculus (house mouse) | 0.0057 | |
| Retinoic acid receptor gamma | Homo sapiens (human) | 0.0064 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.275 | |
| Retinoic acid receptor gamma | Mus musculus (house mouse) | 0.004 | |
| Retinoic acid receptor beta | Mus musculus (house mouse) | 0.005 | |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | 0.576 | |
| Nuclear receptor ROR-alpha | Homo sapiens (human) | 0.1995 | |
| Alpha-synuclein | Homo sapiens (human) | 3 | |
| Cellular retinoic acid-binding protein 1 | Gallus gallus (chicken) | 0.5233 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.358 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.275 | |
| Retinoic acid receptor RXR-gamma | Homo sapiens (human) | 0.35 | |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | 0.1995 | |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 5.3 | |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | 0.82 | |
| 60 kDa chaperonin | Escherichia coli | 6.7 | |
| 10 kDa chaperonin | Escherichia coli | 6.7 | |
| Nuclear receptor ROR-beta | Homo sapiens (human) | 0.1259 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (73.33) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Bradley, KA; Damoiseaux, R; Gillespie, EJ; Huang, J; Manchester, M; Rogers, J; Sanchez, AM; Saxe, JP; Thomas, D | 1 |
| Bigg, HF; Cawston, TE; Clark, IM; McLeod, R; Waters, JG | 1 |
| Alsayed, Y; Bokoch, G; Kalvakolanu, DV; Lekmine, F; Mahmud, N; Minucci, S; Platanias, LC; Uddin, S | 1 |
| Binétruy, B; Bost, F; Caron, L; Dani, C; Le Marchand-Brustel, Y; Marchetti, I | 1 |
| Hatakeyama, D; Ito, H; Kato, K; Kozawa, O; Matsuno, H; Niwa, M; Shibata, T; Tatematsu, N; Uematsu, T | 1 |
| Yung, BY | 1 |
| Dohi, S; Hanai, Y; Hirade, K; Katagiri, Y; Kozawa, O; Matsushima-Nishiwaki, R; Takai, S; Tanabe, K; Tokuda, H | 1 |
| Boeuf, H; Dembele, D; Duval, D; Feraud, O; Gauthereau, X; Menager, J; Pradier, L; Rallu, M; Saucourt, C; Thibault, C; Trouillas, M | 1 |
| Hou, KZ; Liu, YP; Luo, Y; Wang, S; Wang, Y | 1 |
| Bartlett, JB; Colston, KW; Dalgleish, AG; Man, HW; Mouratidis, PX; Muller, GW; Stirling, D | 1 |
| Chen, Q; Pai, T; Ross, AC; Wu, Y | 1 |
| De Genaro, P; Politi, LE; Rotstein, NP; Simón, MV | 1 |
| Gui, S; Wang, B; Wang, Y; Yan, Y; Zhou, J; Zhou, Q | 1 |
| Cui, Y; Ding, J; Li, HR; Sun, GJ; Wang, J; Wang, SJ; Zhang, JX | 1 |
15 other study(ies) available for sb 203580 and tretinoin
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Amiodarone and bepridil inhibit anthrax toxin entry into host cells.
Topics: Amiodarone; Animals; Anthrax; Antigens, Bacterial; Bacterial Toxins; Bepridil; Cell Line; Cell Survival; Chloroquine; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Macrophages, Peritoneal; Male; Mice; Molecular Structure; Rats; Rats, Inbred F344; Time Factors | 2007 |
Mechanisms of induction of human tissue inhibitor of metalloproteinases-1 (TIMP-1) gene expression by all-trans retinoic acid in combination with basic fibroblast growth factor.
Topics: Cells, Cultured; Cycloheximide; Drug Synergism; Fibroblast Growth Factor 2; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Matrix Metalloproteinase 1; Mitogen-Activated Protein Kinases; Pyridines; Receptors, Retinoic Acid; Retinoid X Receptors; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transcription Factors; Tretinoin | 2000 |
Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to all-trans-retinoic acid.
Topics: Cell Differentiation; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; rac1 GTP-Binding Protein; Tretinoin; Tumor Cells, Cultured | 2001 |
Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage.
Topics: Adipocytes; Animals; Butadienes; Cell Lineage; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; Myocardium; Neurons; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Binding; Pyridines; Receptors, Cytoplasmic and Nuclear; RNA; Signal Transduction; Stem Cells; Time Factors; Transcription Factors; Tretinoin | 2002 |
Upregulation by retinoic acid of transforming growth factor-beta-stimulated heat shock protein 27 induction in osteoblasts: involvement of mitogen-activated protein kinases.
Topics: Animals; Blotting, Northern; Cell Line; Enzyme Activation; Flavonoids; Heat-Shock Proteins; Imidazoles; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta; Tretinoin; Up-Regulation | 2002 |
c-Myc-mediated expression of nucleophosmin/B23 decreases during retinoic acid-induced differentiation of human leukemia HL-60 cells.
Topics: Antibodies, Monoclonal; Blotting, Western; Cell Differentiation; Chromatin Immunoprecipitation; Down-Regulation; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Imidazoles; Nuclear Proteins; Nucleophosmin; Oligonucleotides, Antisense; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; Pyridines; Temperature; Time Factors; Transcription, Genetic; Tretinoin | 2004 |
Modulation by the steroid/thyroid hormone superfamily of TGF-beta-stimulated VEGF release from vascular smooth muscle cells.
Topics: Animals; Calcitriol; Cells, Cultured; Cholecalciferol; Corticosterone; Dexamethasone; Enzyme Inhibitors; Gonadal Steroid Hormones; Imidazoles; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Steroids; Thyroid Hormones; Transforming Growth Factor beta; Tretinoin; Vascular Endothelial Growth Factor A | 2006 |
Bcl2, a transcriptional target of p38alpha, is critical for neuronal commitment of mouse embryonic stem cells.
Topics: Animals; Apoptosis; Cell Differentiation; Cell Line; Embryonic Stem Cells; Gene Expression; Imidazoles; Mice; Mitogen-Activated Protein Kinase 14; Neurons; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyridines; Transcription, Genetic; Tretinoin | 2008 |
[Effect of mitogen-activated protein kinases on ATRA-induced differentiation of NB4 cells].
Topics: Cell Differentiation; Cell Division; Cell Line, Tumor; Enzyme Inhibitors; Flow Cytometry; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Pyridines; Signal Transduction; Tretinoin | 2008 |
Antiproliferative effects of CC-8062 and CC-8075 in pancreatic cancer cells.
Topics: Alitretinoin; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Tretinoin | 2009 |
All-trans-retinoic acid and Erk1/2 signaling synergistically regulate the expression of CD300B in human monocytic cells.
Topics: Cell Line, Tumor; Flavonoids; Flow Cytometry; Gene Expression Regulation; Humans; Imidazoles; MAP Kinase Signaling System; Microscopy, Confocal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Monocytes; Protein Kinase Inhibitors; Pyridines; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tretinoin | 2011 |
Retinoic acid promotes apoptosis and differentiation in photoreceptors by activating the P38 MAP kinase pathway.
Topics: Animals; Animals, Newborn; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Differentiation; Cell Survival; Cells, Cultured; Docosahexaenoic Acids; Enzyme Inhibitors; Imidazoles; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Microscopy, Confocal; Microscopy, Fluorescence; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Photoreceptor Cells, Vertebrate; Pyridines; Rats; Rats, Wistar; Retinal Neurons; Signal Transduction; Tretinoin | 2013 |
A novel all-trans retinoid acid derivatives inhibits the migration of breast cancer cell lines MDA-MB-231 via myosin light chain kinase involving p38-MAPK pathway.
Topics: Antineoplastic Agents; Azepines; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Inhibitory Concentration 50; Myosin-Light-Chain Kinase; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Retinoids; Tretinoin | 2013 |
WY14643 combined with all-trans retinoic acid acts via p38 MAPK to induce "browning" of white adipocytes in mice.
Topics: 3T3-L1 Cells; Adipocytes, Brown; Adipocytes, White; Animals; Cell Differentiation; Drug Synergism; Gene Expression Regulation; Imidazoles; Ion Channels; Male; Mice; Mitochondrial Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; PPAR alpha; Pyridines; Pyrimidines; RNA, Messenger; Signal Transduction; Tretinoin; Uncoupling Protein 1 | 2015 |