sb 203580 has been researched along with thromboxane a2 in 10 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (thromboxane a2) | Trials (thromboxane a2) | Recent Studies (post-2010) (thromboxane a2) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 5,617 | 224 | 429 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, MJ; Farndale, RW; Lee, JC; Morton, LF; Rawlinson, L; Saklatvala, J; Sarsfield, S; Waller, RJ | 1 |
| Börsch-Haubold, AG; Pasquet, S; Watson, SP | 1 |
| Akkerman, JW; Gorter, G; van Willigen, G | 1 |
| Akkerman, JW; Bos, JL; Franke, B; Gorter, G; Hackeng, CM; Relou, IA; van Rijn , HJ | 1 |
| Benati, D; Berton, G; Gaino, S; Minuz, P; Ortolani, R; Santonastaso, CL; Tommasoli, RM; Zancanaro, C; Zuliani, V | 1 |
| Balduini, C; Canobbio, I; Reineri, S; Sinigaglia, F; Torti, M | 1 |
| Catapano, AL; Inoue, H; Norata, GD; Pellegatta, F; Pirillo, A | 1 |
| Bailey, SR; Brooks, AC; Cunningham, FM; Elliott, J; Menzies-Gow, NJ; Wheeler-Jones, C | 1 |
| Hu, H; Huang, Z; Li, N; Liu, P; Zhu, L | 1 |
| Doi, T; Enomoto, Y; Iida, H; Iida, Y; Iwama, T; Kozawa, O; Kuroyanagi, G; Matsushima-Nishiwaki, R; Ogura, S; Otsuka, T; Tanabe, K; Tokuda, H; Tsujimoto, M; Yamamoto, N | 1 |
10 other study(ies) available for sb 203580 and thromboxane a2
| Article | Year |
|---|---|
Role for p38 mitogen-activated protein kinase in platelet aggregation caused by collagen or a thromboxane analogue.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Collagen; Enzyme Activation; Enzyme Inhibitors; Heat-Shock Proteins; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Molecular Sequence Data; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Pyridines; Thromboxane A2; Thromboxanes | 1996 |
Direct inhibition of cyclooxygenase-1 and -2 by the kinase inhibitors SB 203580 and PD 98059. SB 203580 also inhibits thromboxane synthase.
Topics: Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Flavonoids; Humans; Imidazoles; In Vitro Techniques; Isoenzymes; Membrane Proteins; Platelet Activation; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins H; Pyridines; Thromboxane A2; Thromboxane-A Synthase | 1998 |
Thrombopoietin increases platelet sensitivity to alpha-thrombin via activation of the ERK2-cPLA2 pathway.
Topics: Animals; Blood Platelets; Carbazoles; Cattle; Cytoplasmic Granules; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Group IV Phospholipases A2; Humans; Imidazoles; Indoles; Indomethacin; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Aggregation; Protein Kinase C; Protein Processing, Post-Translational; Pyridines; Serotonin; Serum Albumin, Bovine; Thrombin; Thrombopoietin; Thromboxane A2 | 2000 |
Low-density lipoprotein activates the small GTPases Rap1 and Ral in human platelets.
Topics: Arachidonic Acid; Blood Platelet Disorders; Blood Platelets; Collagen; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Glutathione Transferase; Humans; Imidazoles; Indomethacin; Ligands; Lipoproteins, LDL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phosphorylation; Pyridines; ral GTP-Binding Proteins; rap1 GTP-Binding Proteins; Recombinant Fusion Proteins; Signal Transduction; Thrombin; Thromboxane A2; Time Factors | 2000 |
Functional role of p38 mitogen activated protein kinase in platelet activation induced by a thromboxane A2 analogue and by 8-iso-prostaglandin F2alpha.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Actin Cytoskeleton; Actins; Adult; Antigens, CD; Blood Platelets; Cell Size; Cytochalasin D; Dinoprost; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; F2-Isoprostanes; Humans; Imidazoles; Integrin beta3; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Microscopy, Electron, Scanning; Mitogen-Activated Protein Kinases; P-Selectin; p38 Mitogen-Activated Protein Kinases; Platelet Activation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Pseudopodia; Pyridines; Stilbenes; Syk Kinase; Thromboxane A2 | 2002 |
A role for p38 MAP kinase in platelet activation by von Willebrand factor.
Topics: Antibodies, Monoclonal; Antigens, CD; Arachidonic Acid; Blood Platelets; Cyclooxygenase Inhibitors; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Precursors; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Activation; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Pyridines; Receptors, IgG; Ristocetin; Signal Transduction; Syk Kinase; Thromboxane A2; Time Factors; von Willebrand Factor | 2004 |
Native LDL and oxidized LDL modulate cyclooxygenase-2 expression in HUVECs through a p38-MAPK, NF-kappaB, CRE dependent pathway and affect PGE2 synthesis.
Topics: Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Epoprostenol; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; Imidazoles; Immunoassay; Immunoblotting; Immunohistochemistry; Indomethacin; Lipoproteins, LDL; Membrane Proteins; NF-kappa B; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Thromboxane A2; Time Factors; Umbilical Veins | 2004 |
Endotoxin-induced activation of equine platelets: evidence for direct activation of p38 MAPK pathways and vasoactive mediator production.
Topics: Animals; Blood Platelets; Dose-Response Relationship, Drug; Endotoxemia; Endotoxins; Enzyme Inhibitors; Female; Horse Diseases; Horses; Imidazoles; Leukocytes; Male; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activation; Pyridines; Signal Transduction; Thromboxane A2 | 2007 |
P2X1-initiated p38 signalling enhances thromboxane A2-induced platelet secretion and aggregation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Benzenesulfonates; Blood Platelets; Cell Degranulation; Cells, Cultured; Female; Gene Expression Regulation; Humans; Imidazoles; Male; MAP Kinase Signaling System; P-Selectin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Aggregation; Purinergic P2X Receptor Antagonists; Pyridines; Receptors, Purinergic P2X1; Thromboxane A2; Young Adult | 2014 |
Rho-kinase regulates human platelet activation induced by thromboxane A2 independently of p38 MAP kinase.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Actin Depolymerizing Factors; Amides; Blood Platelets; Enzyme Inhibitors; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activation; Pyridines; rho-Associated Kinases; Signal Transduction; Thromboxane A2 | 2015 |