Page last updated: 2024-09-05

sb 203580 and threonine

sb 203580 has been researched along with threonine in 20 studies

Compound Research Comparison

Studies (sb 203580)	Trials (sb 203580)	Recent Studies (post-2010) (sb 203580)	Studies (threonine)	Trials (threonine)	Recent Studies (post-2010) (threonine)
3,489	4	1,137	10,383	98	2,176

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (15.00)	18.2507
2000's	14 (70.00)	29.6817
2010's	3 (15.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Adams, JL; Bower, MJ; Goldsmith, EJ; Gum, RJ; Kumar, S; Lee, JC; Livi, GP; McLaughlin, MM; Wang, Z; Young, PR	1
Croft, G; de Laszlo, S; Frantz, B; Hacker, C; Hermes, J; Li, B; Libby, B; Lisnock, J; Liverton, N; LoGrasso, P; O'Keefe, SJ; O'Neill, EA; Smith, A; Tebben, A	1
Adams, JL; Jiang, MS; Kumar, S; Lee, JC	1
Gon, Y; Hashimoto, S; Horie, T; Jibiki, I; Kudoh, S; Matsumoto, K; Takeshita, I; Takizawa, H	1
Bristol, JR; Chen, G; Fitzgibbon, MJ; Pazhanisamy, S; Porter, MD	1
Agell, N; Bachs, O; Casanovas, O; Estanyol, JM; Itarte, E; Miró, F	1
Coxon, PY; Klein, JB; McLeish, KR; Pierce, W; Ping, P; Powell, DW; Rane, MJ; Webster, R	1
Adachi, M; Imai, K; Itoh, F; Nakahata, A; Nakayama, I; Takekawa, M; Taya, Y; Tsukuda, H	1
Ammendola, S; Bonini, P; Cozzolino, F; De Chiara, G; Dello Sbarba, P; Garaci, E; Labardi, D; Lucibello, M; Marlier, LN; Nencioni, L; Palamara, AT; Rosini, P; Russo, T; Torcia, M; Zambrano, N	1
Ewton, DZ; Friedman, E; Jin, K; Kim, GY; Mercer, SE; Yan, Z	1
Horwitz, SB; Yang, CP	1
Griendling, KK; Rocic, P; Seshiah, P	1
Lin, C; Liu, ZR; Yang, L	1
Blondeau, JP; Corrèze, C; Pomérance, M	1
Foster, GH; Rubin, BK; Shinkai, M	1
Bastow, ER; Blenis, J; Lamb, KJ; Lewthwaite, JC; Pitsillides, AA; Wheeler-Jones, CP	1
Kawanishi, M; Koizumi, K; Nishimura, M; Saiki, I; Sakurai, H; Shin, MS; Singhirunnusorn, P; Suzuki, S	1
Chen, B; Du, J; Guo, X; Huang, Q; Huang, X; Li, Q; Liu, H	1
Kapus, A; Malam, Z; Marshall, JC; Parodo, J; Szaszi, K; Waheed, F	1
Damaj, MI; Jayanthi, LD; Mannangatti, P; NarasimhaNaidu, K; Ramamoorthy, S	1

Other Studies

20 other study(ies) available for sb 203580 and threonine

Article	Year
Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket. The Journal of biological chemistry, 1998, Jun-19, Volume: 273, Issue:25 Topics: Adenosine Triphosphate; Amino Acid Substitution; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Crystallography, X-Ray; Enzyme Inhibitors; HeLa Cells; Histidine; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Methionine; Mitogen-Activated Protein Kinase 12; Mitogen-Activated Protein Kinase 13; Mitogen-Activated Protein Kinases; Models, Molecular; Mutagenesis, Site-Directed; p38 Mitogen-Activated Protein Kinases; Protein Conformation; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Structure-Activity Relationship; Threonine	1998
Molecular basis for p38 protein kinase inhibitor specificity. Biochemistry, 1998, Nov-24, Volume: 37, Issue:47 Topics: Adenosine Triphosphate; Base Sequence; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Imidazoles; Methionine; Mitogen-Activated Protein Kinases; Models, Molecular; Molecular Sequence Data; Mutagenesis, Insertional; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrroles; Threonine	1998
Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase. Biochemical and biophysical research communications, 1999, Oct-05, Volume: 263, Issue:3 Topics: Animals; Cell Line; COS Cells; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Kinetics; Mitogen-Activated Protein Kinases; Models, Chemical; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Recombinant Proteins; Threonine; Transfection; Tyrosine	1999
Diesel exhaust particles activate p38 MAP kinase to produce interleukin 8 and RANTES by human bronchial epithelial cells and N-acetylcysteine attenuates p38 MAP kinase activation. American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:1 Topics: Acetylcysteine; Blotting, Western; Bronchi; Cells, Cultured; Chemokine CCL5; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Humans; Imidazoles; Interleukin-8; Mitogen-Activated Protein Kinases; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; Threonine; Tyrosine; Vehicle Emissions	2000
Kinetic mechanism of the p38-alpha MAP kinase: phosphoryl transfer to synthetic peptides. Biochemistry, 2000, Feb-29, Volume: 39, Issue:8 Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Imidazoles; Kinetics; Mitogen-Activated Protein Kinases; Molecular Sequence Data; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphorylation; Proline; Protein Binding; Pyridines; Serine; Threonine; Viscosity	2000
Osmotic stress regulates the stability of cyclin D1 in a p38SAPK2-dependent manner. The Journal of biological chemistry, 2000, Nov-10, Volume: 275, Issue:45 Topics: Arsenites; Blotting, Western; Calcium Chloride; Cell Division; Cell Line; Cyclin D1; Cysteine Endopeptidases; Down-Regulation; Enzyme Inhibitors; Escherichia coli; Glutathione Transferase; Humans; Hydrogen Peroxide; Imidazoles; Kinetics; Magnesium Chloride; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Osmosis; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Point Mutation; Precipitin Tests; Proteasome Endopeptidase Complex; Pyridines; Pyrimidines; Recombinant Fusion Proteins; RNA Processing, Post-Transcriptional; Sodium Chloride; Threonine; Time Factors; Tumor Cells, Cultured; Ubiquitins	2000
p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils. The Journal of biological chemistry, 2001, Feb-02, Volume: 276, Issue:5 Topics: 3-Phosphoinositide-Dependent Protein Kinases; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Inhibitors; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 3; MAP Kinase Kinase 6; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositols; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Serine; Threonine	2001
p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation. The EMBO journal, 2000, Dec-01, Volume: 19, Issue:23 Topics: Animals; Anisomycin; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Northern; Cell Nucleus; COS Cells; DNA Damage; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Gamma Rays; Glutathione Transferase; Humans; Hydrogen Peroxide; Imidazoles; Luciferases; Methyl Methanesulfonate; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Proteins; Plasmids; Precipitin Tests; Pyridines; Recombinant Fusion Proteins; Serine; Serine Proteinase Inhibitors; Signal Transduction; Threonine; Time Factors; Transfection; Tumor Suppressor Protein p53; Ultraviolet Rays	2000
Nerve growth factor inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation, and cytochrome c release. The Journal of biological chemistry, 2001, Oct-19, Volume: 276, Issue:42 Topics: Animals; Apoptosis; B-Lymphocytes; Cell Nucleus; Cells, Cultured; Cytochrome c Group; Cytosol; DNA Fragmentation; Enzyme Inhibitors; Humans; Imidazoles; Immunologic Memory; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Microscopy, Fluorescence; Mitochondria; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nerve Growth Factor; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Pyridines; Rats; Recombinant Proteins; Serine; Threonine; Time Factors	2001
The stress-activated protein kinases p38 alpha and JNK1 stabilize p21(Cip1) by phosphorylation. The Journal of biological chemistry, 2002, Aug-16, Volume: 277, Issue:33 Topics: Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Imidazoles; Mitogen-Activated Protein Kinase 14; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Serine; Signal Transduction; Threonine; Transforming Growth Factor beta; Tumor Cells, Cultured; Up-Regulation	2002
Distinct mechanisms of taxol-induced serine phosphorylation of the 66-kDa Shc isoform in A549 and RAW 264.7 cells. Biochimica et biophysica acta, 2002, Jun-12, Volume: 1590, Issue:1-3 Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Antineoplastic Agents, Phytogenic; Butadienes; Cell Line; Enzyme Inhibitors; Gene Expression; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Proteins; Pyridines; Serine; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Threonine; Tumor Necrosis Factor-alpha	2002
Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells. The Journal of biological chemistry, 2003, Sep-19, Volume: 278, Issue:38 Topics: Acetylcysteine; Angiotensin II; Animals; Aorta; Azoles; Blotting, Western; Carrier Proteins; Cells, Cultured; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Genes, Dominant; Imidazoles; Intracellular Signaling Peptides and Proteins; Isoindoles; Muscle, Smooth, Vascular; Okadaic Acid; Onium Compounds; Organoselenium Compounds; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Protein Phosphatase 2; Pyridines; Rats; Reactive Oxygen Species; Serine; Threonine; Time Factors	2003
Signaling to the DEAD box--regulation of DEAD-box p68 RNA helicase by protein phosphorylations. Cellular signalling, 2005, Volume: 17, Issue:12 Topics: DEAD-box RNA Helicases; HeLa Cells; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinases; Pyridines; RNA Helicases; Signal Transduction; Threonine; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine	2005
p38 mitogen-activated protein kinase contributes to cell cycle regulation by cAMP in FRTL-5 thyroid cells. European journal of endocrinology, 2005, Volume: 153, Issue:1 Topics: Animals; CDC2-CDC28 Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Cyclin-Dependent Kinase 2; Enzyme Inhibitors; G1 Phase; Hypoglycemic Agents; Imidazoles; Insulin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; S Phase; Signal Transduction; Threonine; Thyroid Gland; Tyrosine	2005
Macrolide antibiotics modulate ERK phosphorylation and IL-8 and GM-CSF production by human bronchial epithelial cells. American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 290, Issue:1 Topics: Anti-Bacterial Agents; Azithromycin; Bronchi; Cells, Cultured; Clarithromycin; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; Interleukin-8; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reference Values; Threonine; Time Factors; Tyrosine	2006
A specific mechanomodulatory role for p38 MAPK in embryonic joint articular surface cell MEK-ERK pathway regulation. The Journal of biological chemistry, 2006, Apr-21, Volume: 281, Issue:16 Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Membrane; Chick Embryo; Densitometry; Dose-Response Relationship, Drug; Erythrocytes; Extracellular Signal-Regulated MAP Kinases; Fibroblast Growth Factor 2; Gene Expression Regulation, Enzymologic; Hyaluronic Acid; Imidazoles; Immunoblotting; Immunochemistry; Immunoprecipitation; Joints; MAP Kinase Signaling System; Models, Biological; Models, Statistical; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-fos; Pyridines; Signal Transduction; Stress, Mechanical; Threonine; Time Factors; Vanadates	2006
TAK1-mediated serine/threonine phosphorylation of epidermal growth factor receptor via p38/extracellular signal-regulated kinase: NF-{kappa}B-independent survival pathways in tumor necrosis factor alpha signaling. Molecular and cellular biology, 2009, Volume: 29, Issue:20 Topics: Anthracenes; Butadienes; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; HeLa Cells; Humans; Imidazoles; Lactones; MAP Kinase Kinase Kinases; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Quinazolines; Resorcinols; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Tumor Necrosis Factor-alpha	2009
Advanced glycation end products induce moesin phosphorylation in murine brain endothelium. Brain research, 2011, Feb-10, Volume: 1373 Topics: Amides; Animals; Blood-Brain Barrier; Brain; Drug Interactions; Endothelial Cells; Endothelium; Enzyme Inhibitors; Female; Gene Expression Regulation; Glycation End Products, Advanced; Imidazoles; Mice; Mice, Inbred C57BL; Microfilament Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; rho-Associated Kinases; Threonine	2011
Pre-B cell colony-enhancing factor (PBEF/Nampt/visfatin) primes neutrophils for augmented respiratory burst activity through partial assembly of the NADPH oxidase. Journal of immunology (Baltimore, Md. : 1950), 2011, Jun-01, Volume: 186, Issue:11 Topics: Blotting, Western; Cell Membrane; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; NADPH Oxidases; Neutrophils; Nicotinamide Phosphoribosyltransferase; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Subunits; Protein Transport; Pyridines; Reactive Oxygen Species; Respiratory Burst; Threonine	2011
A Role for p38 Mitogen-activated Protein Kinase-mediated Threonine 30-dependent Norepinephrine Transporter Regulation in Cocaine Sensitization and Conditioned Place Preference. The Journal of biological chemistry, 2015, Apr-24, Volume: 290, Issue:17 Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Gene Products, tat; Imidazoles; Male; Mice; Mice, Inbred C57BL; Motor Activity; Norepinephrine Plasma Membrane Transport Proteins; Nucleus Accumbens; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prefrontal Cortex; Protein Kinase Inhibitors; Pyridines; Synaptosomes; Threonine; Up-Regulation	2015