sb 203580 has been researched along with thalidomide in 5 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (thalidomide) | Trials (thalidomide) | Recent Studies (post-2010) (thalidomide) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 9,789 | 1,385 | 4,342 |
| Protein | Taxonomy | sb 203580 (IC50) | thalidomide (IC50) |
|---|---|---|---|
| Cereblon isoform 4 | Magnetospirillum gryphiswaldense | 7.8 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.37 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 0.5 | |
| DNA damage-binding protein 1 | Homo sapiens (human) | 1.38 | |
| Protein cereblon | Homo sapiens (human) | 1.38 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Abrahamsen, MS; Maheswaran, SK; Malazdrewich, C; Thumbikat, P | 1 |
| Dennis, PA; Figg, WD; Lepper, ER; Warfel, NA; Zhang, C | 1 |
| Jin, SH; Kim, TI; Kim, WH; Yang, KM | 1 |
| Ge, YX; Li, YY; Liu, XG; Liu, YL; Wei, XH; Wu, CY; Xin, WJ; Xu, JT; Zang, Y; Zhang, T | 1 |
5 other study(ies) available for sb 203580 and thalidomide
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Pharmacological inhibition of Mannheimia haemolytica lipopolysaccharide and leukotoxin-induced cytokine expression in bovine alveolar macrophages.
Topics: Animals; Anti-Inflammatory Agents; Cattle; Cells, Cultured; Cytokines; Dexamethasone; Exotoxins; Gene Expression Regulation; Imidazoles; Interleukin-1; Interleukin-8; Lipopolysaccharides; Macrophages, Alveolar; Mannheimia haemolytica; Pentoxifylline; Pyridines; RNA, Messenger; Rolipram; Tetrahydropapaveroline; Thalidomide; Tumor Necrosis Factor-alpha | 2004 |
Importance of the stress kinase p38alpha in mediating the direct cytotoxic effects of the thalidomide analogue, CPS49, in cancer cells and endothelial cells.
Topics: Animals; Butadienes; Cell Death; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Endothelial Cells; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; Imidazoles; Mice; Mice, SCID; Mitogen-Activated Protein Kinase 14; Neoplasms; Nitriles; Pyridines; Structure-Activity Relationship; Thalidomide; Xenograft Model Antitumor Assays | 2006 |
Thalidomide destabilizes cyclooxygenase-2 mRNA by inhibiting p38 mitogen-activated protein kinase and cytoplasmic shuttling of HuR.
Topics: Antigens, Surface; Caco-2 Cells; Cyclooxygenase 2; Cytoplasm; ELAV Proteins; ELAV-Like Protein 1; Humans; Imidazoles; Interleukin-1beta; p38 Mitogen-Activated Protein Kinases; Protein Transport; Pyridines; RNA Stability; RNA-Binding Proteins; Thalidomide | 2007 |
p38 activation in uninjured primary afferent neurons and in spinal microglia contributes to the development of neuropathic pain induced by selective motor fiber injury.
Topics: Animals; Denervation; Enzyme Activation; Enzyme Inhibitors; Ganglia, Spinal; Hyperalgesia; Hypesthesia; Imidazoles; Immunohistochemistry; Lumbosacral Region; Male; Microglia; Motor Neurons; Nerve Fibers; Neuralgia; Neurons, Afferent; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerve Roots; Thalidomide; Time Factors; Tumor Necrosis Factor-alpha | 2007 |