Compounds > sb 203580
Page last updated: 2024-09-05

sb 203580 and sulindac

sb 203580 has been researched along with sulindac in 4 studies

Compound Research Comparison

Studies
(sb 203580)		Trials
(sb 203580)		Recent Studies (post-2010)
(sb 203580)		Studies
(sulindac)		Trials
(sulindac)		Recent Studies (post-2010) (sulindac)
3,48941,1371,462202305

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)sulindac (IC50)
Aldo-keto reductase family 1 member B10Homo sapiens (human)2.69
Aldo-keto reductase family 1 member B1Homo sapiens (human)2.69
Aldo-keto reductase family 1 member B1Bos taurus (cattle)0.293
Prostaglandin G/H synthase 2Homo sapiens (human)8.8

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bradbury, CM; Gius, D; Horikoshi, N; Markovina, S; Rene, LM; Wei, SJ; Zoberi, I1
Kim, CH; Kim, JY; Kim, KS; Lee, BJ; Lee, JG; Song, KS; Yoon, JH1
Lee, E; Lee, YJ; Lim, SJ1
Kim, YB; Moon, Y; Yang, H1

Other Studies

4 other study(ies) available for sb 203580 and sulindac

ArticleYear
Indomethacin-induced radiosensitization and inhibition of ionizing radiation-induced NF-kappaB activation in HeLa cells occur via a mechanism involving p38 MAP kinase.
    Cancer research, 2001, Oct-15, Volume: 61, Issue:20

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Nucleus; Cell Survival; DNA; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; I-kappa B Proteins; Imidazoles; Indomethacin; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyridines; Radiation Tolerance; Sodium Salicylate; Sulindac; Transfection

2001
Sulindac sulfide-induced apoptosis in sinonasal cancer cells.
    Acta oto-laryngologica, 2005, Volume: 125, Issue:2

    Topics: Amino Acid Chloromethyl Ketones; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma, Squamous Cell; Caspase Inhibitors; Flavonoids; Fluorescence; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Paranasal Sinus Neoplasms; Pyridines; Signal Transduction; Sulindac

2005
p38MAPK inhibitor SB203580 sensitizes human SNU-C4 colon cancer cells to exisulind-induced apoptosis.
    Oncology reports, 2006, Volume: 16, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Colonic Neoplasms; Flavonoids; HCT116 Cells; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Sulindac

2006
Up-regulation of early growth response gene 1 (EGR-1) via ERK1/2 signals attenuates sulindac sulfide-mediated cytotoxicity in the human intestinal epithelial cells.
    Toxicology and applied pharmacology, 2007, Sep-01, Volume: 223, Issue:2

    Topics: Animals; Apoptosis; Blotting, Western; Butadienes; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Epithelial Cells; ets-Domain Protein Elk-1; HCT116 Cells; HT29 Cells; Humans; Imidazoles; Intestinal Mucosa; Intestines; Luciferases; Microscopy, Confocal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulindac; Transfection; Up-Regulation

2007