sb 203580 has been researched along with sulindac in 4 studies
Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (sulindac) | Trials (sulindac) | Recent Studies (post-2010) (sulindac) |
---|---|---|---|---|---|
3,489 | 4 | 1,137 | 1,462 | 202 | 305 |
Protein | Taxonomy | sb 203580 (IC50) | sulindac (IC50) |
---|---|---|---|
Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | 2.69 | |
Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | 2.69 | |
Aldo-keto reductase family 1 member B1 | Bos taurus (cattle) | 0.293 | |
Prostaglandin G/H synthase 2 | Homo sapiens (human) | 8.8 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Bradbury, CM; Gius, D; Horikoshi, N; Markovina, S; Rene, LM; Wei, SJ; Zoberi, I | 1 |
Kim, CH; Kim, JY; Kim, KS; Lee, BJ; Lee, JG; Song, KS; Yoon, JH | 1 |
Lee, E; Lee, YJ; Lim, SJ | 1 |
Kim, YB; Moon, Y; Yang, H | 1 |
4 other study(ies) available for sb 203580 and sulindac
Article | Year |
---|---|
Indomethacin-induced radiosensitization and inhibition of ionizing radiation-induced NF-kappaB activation in HeLa cells occur via a mechanism involving p38 MAP kinase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Nucleus; Cell Survival; DNA; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; I-kappa B Proteins; Imidazoles; Indomethacin; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyridines; Radiation Tolerance; Sodium Salicylate; Sulindac; Transfection | 2001 |
Sulindac sulfide-induced apoptosis in sinonasal cancer cells.
Topics: Amino Acid Chloromethyl Ketones; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma, Squamous Cell; Caspase Inhibitors; Flavonoids; Fluorescence; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Paranasal Sinus Neoplasms; Pyridines; Signal Transduction; Sulindac | 2005 |
p38MAPK inhibitor SB203580 sensitizes human SNU-C4 colon cancer cells to exisulind-induced apoptosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Colonic Neoplasms; Flavonoids; HCT116 Cells; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Sulindac | 2006 |
Up-regulation of early growth response gene 1 (EGR-1) via ERK1/2 signals attenuates sulindac sulfide-mediated cytotoxicity in the human intestinal epithelial cells.
Topics: Animals; Apoptosis; Blotting, Western; Butadienes; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Epithelial Cells; ets-Domain Protein Elk-1; HCT116 Cells; HT29 Cells; Humans; Imidazoles; Intestinal Mucosa; Intestines; Luciferases; Microscopy, Confocal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulindac; Transfection; Up-Regulation | 2007 |