Compounds > sb 203580
Page last updated: 2024-09-05

sb 203580 and sc 514

sb 203580 has been researched along with sc 514 in 4 studies

Compound Research Comparison

Studies
(sb 203580)		Trials
(sb 203580)		Recent Studies (post-2010)
(sb 203580)		Studies
(sc 514)		Trials
(sc 514)		Recent Studies (post-2010) (sc 514)
3,48941,13750035

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)sc 514 (IC50)
Inhibitor of nuclear factor kappa-B kinase subunit betaHomo sapiens (human)1.65

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Chen, Z; Doyle, T; Muscoli, C; Obeid, LM; Salvemini, D1
Hosokawa, I; Hosokawa, Y; Matsuo, T; Nakae, H; Ozaki, K1
Huang, X; Jiang, Y; Luo, W; Pinhu, L; Qin, Y; Sooranna, SR; Xiang, S; Zeng, Y1

Other Studies

4 other study(ies) available for sb 203580 and sc 514

ArticleYear
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
Intraplantar-injected ceramide in rats induces hyperalgesia through an NF-κB- and p38 kinase-dependent cyclooxygenase 2/prostaglandin E2 pathway.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:8

    Topics: Animals; Antibodies, Monoclonal; Ceramides; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Extremities; Hot Temperature; Hyperalgesia; Imidazoles; Injections; Male; Models, Biological; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pain Threshold; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiophenes; Touch

2011
Interleukin (IL)-17A synergistically enhances CC chemokine ligand 20 production in IL-1β-stimulated human gingival fibroblasts.
    Human immunology, 2012, Volume: 73, Issue:1

    Topics: Blotting, Western; Cells, Cultured; Chemokine CCL20; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Gingiva; Humans; I-kappa B Kinase; Imidazoles; Interleukin-17; Interleukin-1beta; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptors, Interleukin-17; Signal Transduction; Thiophenes

2012
Lipopolysaccharide-Binding Protein Downregulates Fractalkine through Activation of p38 MAPK and NF-
    Mediators of inflammation, 2017, Volume: 2017

    Topics: A549 Cells; Acute-Phase Proteins; Animals; Carrier Proteins; Chemokine CX3CL1; Enzyme-Linked Immunosorbent Assay; Humans; Imidazoles; Lipopolysaccharides; Lung; Male; Membrane Glycoproteins; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Peptides; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiophenes

2017