sb 203580 has been researched along with sb 216995 in 4 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (sb 216995) | Trials (sb 216995) | Recent Studies (post-2010) (sb 216995) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 5 | 0 | 0 |
| Protein | Taxonomy | sb 203580 (IC50) | sb 216995 (IC50) |
|---|---|---|---|
| Chain A, MAP KINASE P38 | Homo sapiens (human) | 0.16 | |
| Chain A, PROTEIN (MAP KINASE P38) | Homo sapiens (human) | 0.16 | |
| Chain A, PROTEIN (MAP KINASE P38) | Homo sapiens (human) | 0.16 | |
| Chain A, Protein (map Kinase P38) | Homo sapiens (human) | 0.16 | |
| Chain A, Extracellular Regulated Kinase 2 | Rattus norvegicus (Norway rat) | 0.16 | |
| Chain A, Extracellular Regulated Kinase 2 | Rattus norvegicus (Norway rat) | 0.16 | |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | 0.057 | |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | 0.057 | |
| Mitogen-activated protein kinase 1 | Rattus norvegicus (Norway rat) | 0.16 | |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | 0.057 | |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | 0.1188 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adams, JL; Badger, AM; Boehm, JC; Bradbeer, J; Breton, JJ; Chabot-Fletcher, MC; Gallagher, TF; Garigipati, RS; Griswold, DE; Hillegass, LM; Laydon, JT; Lee, JC; Sheldrake, PL; Smietana, JM; Sorenson, ME | 1 |
| Abdel-Meguid, S; Adams, JL; Boehm, JC; Canagarajah, BJ; Cobb, MH; Goldsmith, EJ; Kassisà , S; Wang, Z; Young, PR | 1 |
| Abadleh, M; Kinkel, K; Laufer, S; Peifer, C; Schollmeyer, D | 1 |
| Barlow, DJ; Ehrman, TM; Hylands, PJ | 1 |
4 other study(ies) available for sb 203580 and sb 216995
| Article | Year |
|---|---|
1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arthritis; Bone Density; Cyclooxygenase Inhibitors; Cytokines; Imidazoles; Lipoxygenase Inhibitors; Mice; Mice, Inbred BALB C; Molecular Structure; Morpholines; Prostaglandin-Endoperoxide Synthases; Protein Kinases; Rats; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 1996 |
Structural basis of inhibitor selectivity in MAP kinases.
Topics: Adenosine Triphosphate; Calcium-Calmodulin-Dependent Protein Kinases; Catalytic Domain; Cell Differentiation; Cell Division; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Imidazoles; Kinetin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Models, Chemical; Models, Molecular; p38 Mitogen-Activated Protein Kinases; Protein Conformation; Purines; Pyridines; Pyrimidines; Structure-Activity Relationship | 1998 |
From five- to six-membered rings: 3,4-diarylquinolinone as lead for novel p38MAP kinase inhibitors.
Topics: Binding Sites; Crystallography, X-Ray; Heterocyclic Compounds, 4 or More Rings; Mitogen-Activated Protein Kinase 10; Models, Molecular; p38 Mitogen-Activated Protein Kinases; Quinolones; Structure-Activity Relationship | 2007 |
In silico search for multi-target anti-inflammatories in Chinese herbs and formulas.
Topics: Anti-Inflammatory Agents; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Databases, Factual; Drug Design; Drugs, Chinese Herbal; Enzyme Inhibitors; JNK Mitogen-Activated Protein Kinases; Medicine, Chinese Traditional; Models, Chemical; Models, Molecular; Molecular Conformation; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase 4 Inhibitors; Structure-Activity Relationship | 2010 |