sb 203580 has been researched along with rwj 68354 in 3 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (rwj 68354) | Trials (rwj 68354) | Recent Studies (post-2010) (rwj 68354) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 5 | 0 | 0 |
| Protein | Taxonomy | sb 203580 (IC50) | rwj 68354 (IC50) |
|---|---|---|---|
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | 0.0067 | |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 1.237 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 1.07 | |
| Neutrophil elastase | Homo sapiens (human) | 0.0063 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 1 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.2 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 1 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.07 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 1.237 | |
| Adenosine receptor A2a | Homo sapiens (human) | 1.032 | |
| Adenosine receptor A1 | Homo sapiens (human) | 0.887 | |
| Mitogen-activated protein kinase 14 | Mus musculus (house mouse) | 1.5 | |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | 0.0067 | |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | 0.0067 | |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | 0.0385 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cavender, DE; Davis, JE; Dodd, JH; Fahmy, B; Henry, JR; Olini, GC; Pellegrino-Gensey, JL; Rupert, KC; Schafer, PH; Siekierka, JJ; Turchi, IJ; Wadsworth, SA | 1 |
| Cavender, DE; Dodd, JH; Henry, JR; Rupert, KC; Schafer, PH; Siekierka, JJ; Turchi, IJ; Wadsworth, SA | 1 |
| Barberia, JT; Carty, TJ; Cortina, SR; Csiki, C; Dipesa, AJ; Dombroski, MA; Elliott, NC; Gabel, CA; Jordan, CK; Labasi, JM; Letavic, MA; Martin, WH; McClure, KF; Peese, KM; Stock, IA; Svensson, L; Sweeney, FJ; Yu, CH | 1 |
3 other study(ies) available for sb 203580 and rwj 68354
| Article | Year |
|---|---|
6-Amino-2-(4-fluorophenyl)-4-methoxy-3- (4-pyridyl)-1H-pyrrolo[2, 3-b]pyridine (RWJ 68354): a potent and selective p38 kinase inhibitor.
Topics: Aminopyridines; Animals; Arthritis, Experimental; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Humans; In Vitro Techniques; Interleukin-1; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Monocytes; p38 Mitogen-Activated Protein Kinases; Pyrroles; Rats; Rats, Inbred Lew; T-Lymphocytes; Tumor Necrosis Factor-alpha | 1998 |
Potent inhibitors of the MAP kinase p38.
Topics: Anti-Inflammatory Agents; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; Tumor Necrosis Factor-alpha | 1998 |
Benzimidazolone p38 inhibitors.
Topics: Benzimidazoles; Enzyme Inhibitors; Imidazoles; Mitogen-Activated Protein Kinase 14; Mitogen-Activated Protein Kinases; Molecular Structure; Pyridines; Structure-Activity Relationship | 2004 |