sb 203580 has been researched along with rtki cpd in 11 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (rtki cpd) | Trials (rtki cpd) | Recent Studies (post-2010) (rtki cpd) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 41 | 0 | 21 |
| 3,489 | 4 | 1,137 | 744 | 0 | 257 |
| Protein | Taxonomy | sb 203580 (IC50) | rtki cpd (IC50) |
|---|---|---|---|
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | 0.125 | |
| Epidermal growth factor receptor | Homo sapiens (human) | 0.1152 | |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | 1.3 | |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | 2.7 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.56 | |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | 0.125 | |
| Epidermal growth factor receptor | Mus musculus (house mouse) | 0.1 | |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | 0.56 | |
| MAP kinase-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | 0.53 | |
| Histamine H3 receptor | Rattus norvegicus (Norway rat) | 1.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Bowden, SG; Breed, J; Campbell, D; Cumming, JG; Jewsbury, PJ; Masters, DJ; McKenzie, CL | 1 |
| Al-Mazaideh, GM; Erdmann, F; Göllner, C; Rohe, A; Schmidt, M; Sippl, W; Wichapong, K | 1 |
| Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A | 1 |
| Plowright, AT; Schade, D | 1 |
| Caballero, E; García-Cárceles, J; Gil, C; Martínez, A | 1 |
| Avkiran, M; Hearse, DJ; Snabaitis, AK | 1 |
| Huang, XL; Lawrence, M; Madara, P; Nanavaty, UB; Pawliczak, R; Shelhamer, JH | 1 |
| Dobashi, K; Ishizuka, T; Kawata, T; Mori, M; Shimizu, Y; Tsukagoshi, H | 1 |
| Chalothorn, D; Faber, JE; Jackson, LF; Lee, DC; Zhang, H | 1 |
| Bagnato, A; Di Castro, V; Elia, G; Natali, PG; Rosanò, L; Spinella, F | 1 |
| Guo, J; Sheng, G; Warner, BW | 1 |
2 review(s) available for sb 203580 and rtki cpd
| Article | Year |
|---|---|
Medicinal Chemistry Approaches to Heart Regeneration.
Topics: Animals; Cell Differentiation; Cell Proliferation; Cellular Reprogramming; Fibroblasts; Humans; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Pluripotent Stem Cells; Regeneration; Signal Transduction; Stem Cells | 2015 |
Kinase Inhibitors as Underexplored Antiviral Agents.
Topics: Animals; Antiviral Agents; Drug Repositioning; Humans; Protein Kinase Inhibitors; Virus Diseases; Viruses | 2022 |
9 other study(ies) available for sb 203580 and rtki cpd
| Article | Year |
|---|---|
Novel, potent and selective anilinoquinazoline and anilinopyrimidine inhibitors of p38 MAP kinase.
Topics: Adenosine Triphosphate; Administration, Oral; Aniline Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Binding Sites; Biological Availability; Crystallography, X-Ray; Humans; In Vitro Techniques; Models, Molecular; p38 Mitogen-Activated Protein Kinases; Protein Binding; Pyrimidines; Quinazolines; Rats; Signal Transduction; Structure-Activity Relationship; Time Factors | 2004 |
Evaluation of potential Myt1 kinase inhibitors by TR-FRET based binding assay.
Topics: Dose-Response Relationship, Drug; Fluorescence Resonance Energy Transfer; Glycolipids; Humans; Membrane Proteins; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Structure-Activity Relationship | 2013 |
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase | 2013 |
Regulation of sarcolemmal Na(+)/H(+) exchange by hydrogen peroxide in adult rat ventricular myocytes.
Topics: Animals; Cells, Cultured; DNA-Binding Proteins; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Genistein; Hydrogen Peroxide; Imidazoles; Immunoblotting; Indoles; Male; Maleimides; Mitogen-Activated Protein Kinases; Myocardium; p38 Mitogen-Activated Protein Kinases; Plant Proteins; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Quinazolines; Rats; Rats, Wistar; Sarcolemma; Signal Transduction; Sodium-Hydrogen Exchangers; src-Family Kinases; Tyrphostins | 2002 |
Oxidative stress induces arachidonate release from human lung cells through the epithelial growth factor receptor pathway.
Topics: Antineoplastic Agents; Arachidonic Acid; Calcium; Cells, Cultured; Cytosol; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Humans; Hydrogen Peroxide; Imidazoles; Ionophores; Lung; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxidants; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phosphorylation; Platelet Activating Factor; Protein Serine-Threonine Kinases; Pyridines; Quinazolines; ras Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha; Tyrosine; Tyrphostins | 2002 |
4-Hydroxy-2-nonenal enhances fibronectin production by IMR-90 human lung fibroblasts partly via activation of epidermal growth factor receptor-linked extracellular signal-regulated kinase p44/42 pathway.
Topics: Acetylcysteine; Aldehydes; Cell Line; Culture Media, Conditioned; ErbB Receptors; Fibroblasts; Fibronectins; Humans; Imidazoles; Lipid Peroxidation; Lung; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Pyridines; Quinazolines; Signal Transduction; Tyrphostins | 2002 |
Transactivation of epidermal growth factor receptor mediates catecholamine-induced growth of vascular smooth muscle.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Anthracenes; Aorta, Thoracic; Bacterial Proteins; Benzopyrans; Butadienes; Catheterization; Cell Division; Dipeptides; ErbB Receptors; Flavonoids; Glycine; Hydroxamic Acids; Imidazoles; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitriles; Organ Culture Techniques; Phenylephrine; Phosphorylation; Protein Processing, Post-Translational; Pyridines; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Thrombin; Tyrphostins | 2004 |
Endothelin-1 stimulates cyclooxygenase-2 expression in ovarian cancer cells through multiple signaling pathways: evidence for involvement of transactivation of the epidermal growth factor receptor.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Endothelin A Receptor Antagonists; Endothelin-1; Enzyme Induction; ErbB Receptors; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Peptides, Cyclic; Protein Kinase Inhibitors; Pyridines; Quinazolines; Receptor, Endothelin A; Signal Transduction; Transcriptional Activation; Tyrphostins | 2004 |
Epidermal growth factor receptor signaling modulates apoptosis via p38alpha MAPK-dependent activation of Bax in intestinal epithelial cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Line; Dose-Response Relationship, Drug; Enterocytes; Epidermal Growth Factor; ErbB Receptors; Gefitinib; Ileum; Imidazoles; Mitochondria; Mitogen-Activated Protein Kinase 14; Phosphorylation; Protein Kinase Inhibitors; Protein Transport; Pyridines; Quinazolines; Rats; RNA Interference; RNA, Small Interfering; Signal Transduction; Time Factors; Tyrphostins | 2007 |