Compounds > sb 203580
Page last updated: 2024-09-05

sb 203580 and rp 73401

sb 203580 has been researched along with rp 73401 in 2 studies

Compound Research Comparison

Studies
(sb 203580)		Trials
(sb 203580)		Recent Studies (post-2010)
(sb 203580)		Studies
(rp 73401)		Trials
(rp 73401)		Recent Studies (post-2010) (rp 73401)
3,48941,13792023

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)rp 73401 (IC50)
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)2.78
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)2.78
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)2.78
3',5'-cyclic-AMP phosphodiesterase Sus scrofa (pig)0.001
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)0.0027
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)2.78
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.5166
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)0.0035
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.5363
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)2.78
Endothelin-1 receptorSus scrofa (pig)0.001
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AHomo sapiens (human)2.78
cAMP-specific 3',5'-cyclic phosphodiesterase 7BHomo sapiens (human)2.78
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10AHomo sapiens (human)2.78

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barlow, DJ; Ehrman, TM; Hylands, PJ1
Belvisi, MG; Birrell, M; Foster, ML; Haddad, EB; Ling, A; McCluskie, K; Webber, SE1

Other Studies

2 other study(ies) available for sb 203580 and rp 73401

ArticleYear
In silico search for multi-target anti-inflammatories in Chinese herbs and formulas.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Anti-Inflammatory Agents; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Databases, Factual; Drug Design; Drugs, Chinese Herbal; Enzyme Inhibitors; JNK Mitogen-Activated Protein Kinases; Medicine, Chinese Traditional; Models, Chemical; Models, Molecular; Molecular Conformation; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase 4 Inhibitors; Structure-Activity Relationship

2010
Role of p38 MAP kinase in LPS-induced airway inflammation in the rat.
    British journal of pharmacology, 2001, Volume: 132, Issue:8

    Topics: Aerosols; Animals; Anti-Inflammatory Agents; Benzamides; Blotting, Western; Cytosol; Dexamethasone; Endotoxins; Enzyme Inhibitors; Humans; Imidazoles; In Vitro Techniques; Interleukin-1; Lipopolysaccharides; Male; Mitogen-Activated Protein Kinases; Monocytes; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase Inhibitors; Pneumonia; Pyridines; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2001