Page last updated: 2024-09-05

sb 203580 and resveratrol

sb 203580 has been researched along with resveratrol in 15 studies

Compound Research Comparison

Studies
(sb 203580)
Trials
(sb 203580)
Recent Studies (post-2010)
(sb 203580)
Studies
(resveratrol)
Trials
(resveratrol)
Recent Studies (post-2010) (resveratrol)
3,48941,13710,9312417,998

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)resveratrol (IC50)
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
M18 aspartyl aminopeptidasePlasmodium falciparum 3D72.242
VifHuman immunodeficiency virus 125.31
DNA dC->dU-editing enzyme APOBEC-3G isoform 1Homo sapiens (human)25.31
Transient receptor potential cation channel subfamily A member 1Homo sapiens (human)0.75
Amyloid-beta precursor proteinHomo sapiens (human)2.6
Cytochrome P450 1A2Homo sapiens (human)3
Prostaglandin G/H synthase 1Ovis aries (sheep)2.025
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.312
Luciferin 4-monooxygenasePhotinus pyralis (common eastern firefly)0.0589
Cytochrome P450 3A4Homo sapiens (human)0.6
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.685
DNA polymerase alpha catalytic subunitHomo sapiens (human)3.3
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)4.9
AromataseHomo sapiens (human)0.96
Cytochrome P450 2C9 Homo sapiens (human)7
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.685
TyrosinaseHomo sapiens (human)5.35
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)1.3972
Nuclear factor NF-kappa-B p105 subunitHomo sapiens (human)2.5
Amine oxidase [flavin-containing] AHomo sapiens (human)2.4945
Prostaglandin G/H synthase 1Homo sapiens (human)0.8517
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.312
Amine oxidase [flavin-containing] BHomo sapiens (human)5.01
Dipeptidyl peptidase 4Homo sapiens (human)0.0006
Cytochrome P450 2C19Homo sapiens (human)3
Prostaglandin G/H synthase 2Homo sapiens (human)1.672
Prostaglandin G/H synthase 2Ovis aries (sheep)3.49
Nuclear factor NF-kappa-B p100 subunit Homo sapiens (human)2.5
Transcription factor p65Homo sapiens (human)2.5
Cytochrome P450 1B1Homo sapiens (human)1.4
Transient receptor potential cation channel subfamily A member 1Rattus norvegicus (Norway rat)1.63
large T antigenBetapolyomavirus macacae26.2

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (20.00)29.6817
2010's12 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jung, SH; Manickam, M; Namasivayam, V; Pillaiyar, T1
Borriello, A; Criniti, V; Cucciolla, V; Della Ragione, F; Indaco, S; Zappia, V1
BrĂ¼ne, B; Loitsch, SM; Rau, O; Schubert-Zsilavecz, M; Stein, JM; Ulrich, S; von Knethen, A1
Fu, J; Liang, M; Low, B1
Burton, DG; Davis, T; Faragher, RG; Fong, NS; Majecha, P; Ostler, EL; Sheerin, A1
Guo, JG; Guo, ZH; Xie, SQ; Zhang, YH1
Chan, C; Cheng, D; Chun, C; Dan, Y; Fangyou, Y; Honglei, X; Lehe, Y; Liangxing, W; Qi, Z; Weixi, Z; Xiaoying, H; Xueding, C; Yang, W; Yuanyuan, L; Zhoucang, Z1
Chen, T; Li, H; Qu, J; Wang, X1
Hintze, TH; Huang, A; Kaley, G; Sun, D; Yan, C; Yang, YM1
Al-Arifi, MN; Ansari, MA; El Gendy, MA; Korashy, HM; Maayah, ZH1
Gweon, EJ; Kim, SJ1
Kondo, A; Kozawa, O; Kuroyanagi, G; Matsushima-Nishiwaki, R; Mizutani, J; Otsuka, T; Tokuda, H; Yamamoto, N1
Kozawa, O; Kuroyanagi, G; Matsushima-Nishiwaki, R; Mizutani, J; Nakakami, A; Otsuka, T; Tokuda, H; Yamamoto, N1
Cao, L; Chen, X; Li, W; Ma, Q; Xiao, X1
Fujita, K; Kainuma, S; Kawabata, T; Kozawa, O; Matsushima-Nishiwaki, R; Otsuka, T; Sakai, G; Tokuda, H1

Reviews

1 review(s) available for sb 203580 and resveratrol

ArticleYear
Inhibitors of Melanogenesis: An Updated Review.
    Journal of medicinal chemistry, 2018, 09-13, Volume: 61, Issue:17

    Topics: alpha-MSH; Biphenyl Compounds; Crystallization; Enzyme Inhibitors; Humans; Melanins; Monophenol Monooxygenase; Peptidomimetics; Radiation, Ionizing; Resveratrol; Signal Transduction; Skin

2018

Other Studies

14 other study(ies) available for sb 203580 and resveratrol

ArticleYear
Antioxidants induce different phenotypes by a distinct modulation of signal transduction.
    FEBS letters, 2002, Dec-18, Volume: 532, Issue:3

    Topics: Antioxidants; Apoptosis; DNA-Binding Proteins; DNA, Complementary; Early Growth Response Protein 1; Enzyme Inhibitors; Flavonoids; HL-60 Cells; Humans; Imidazoles; Immediate-Early Proteins; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Models, Chemical; Phenotype; Phenylethyl Alcohol; Phosphorylation; Proto-Oncogene Proteins c-jun; Pyridines; Pyrrolidines; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes; Thiocarbamates; Time Factors; Transcription Factors; Up-Regulation

2002
Peroxisome proliferator-activated receptor gamma as a molecular target of resveratrol-induced modulation of polyamine metabolism.
    Cancer research, 2006, Jul-15, Volume: 66, Issue:14

    Topics: Acetyltransferases; Antineoplastic Agents, Phytogenic; Biogenic Polyamines; Caco-2 Cells; Cell Growth Processes; Colonic Neoplasms; Enzyme Activation; HCT116 Cells; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; PPAR gamma; Pyridines; Resveratrol; Stilbenes; Transcription, Genetic; Transfection

2006
p38 mitogen-activated protein kinase mediates sidestream cigarette smoke-induced endothelial permeability.
    Journal of pharmacological sciences, 2007, Volume: 104, Issue:3

    Topics: Blood-Air Barrier; Blotting, Western; Capillary Permeability; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Fluorescent Antibody Technique; Humans; Imidazoles; Myosin Light Chains; p38 Mitogen-Activated Protein Kinases; Pulmonary Artery; Pyridines; Resveratrol; rho GTP-Binding Proteins; Stilbenes; Tobacco Smoke Pollution

2007
Resveratrol, but not dihydroresveratrol, induces premature senescence in primary human fibroblasts.
    Age (Dordrecht, Netherlands), 2011, Volume: 33, Issue:4

    Topics: beta-Galactosidase; Cell Line; Cell Proliferation; Cells, Cultured; Cellular Senescence; Dose-Response Relationship, Drug; Fibroblasts; Humans; Imidazoles; Ki-67 Antigen; p38 Mitogen-Activated Protein Kinases; Pyridines; Resveratrol; Stilbenes

2011
[Involvement of p38-p53 signal pathway in resveratrol-induced apoptosis in MCF-7 cells].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2011, Volume: 46, Issue:11

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzothiazoles; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Imidazoles; MCF-7 Cells; p38 Mitogen-Activated Protein Kinases; Pyridines; Resveratrol; Signal Transduction; Stilbenes; Toluene; Tumor Suppressor Protein p53

2011
Resveratrol downregulates acute pulmonary thromboembolism-induced pulmonary artery hypertension via p38 mitogen-activated protein kinase and monocyte chemoattractant protein-1 signaling in rats.
    Life sciences, 2012, May-22, Volume: 90, Issue:19-20

    Topics: Animals; Blotting, Western; Chemokine CCL2; Down-Regulation; Enzyme Inhibitors; Fluorescent Antibody Technique; Hypertension, Pulmonary; Imidazoles; Immunohistochemistry; Indicators and Reagents; Male; p38 Mitogen-Activated Protein Kinases; Pulmonary Embolism; Pyridines; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes

2012
p38 inhibitor SB203580 sensitizes the resveratrol-induced apoptosis in human lung adenocarcinoma (A549) cells.
    Journal of biochemical and molecular toxicology, 2012, Volume: 26, Issue:7

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Survival; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Lung Neoplasms; Membrane Potential, Mitochondrial; p38 Mitogen-Activated Protein Kinases; Pyridines; Resveratrol; Stilbenes

2012
Altered MAPK signaling in progressive deterioration of endothelial function in diabetic mice.
    Diabetes, 2012, Volume: 61, Issue:12

    Topics: Animals; Anthracenes; Butadienes; Diabetes Mellitus, Type 2; Extracellular Signal-Regulated MAP Kinases; Imidazoles; Immunoblotting; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mitogen-Activated Protein Kinases; Nitriles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptors, Leptin; Resveratrol; Signal Transduction; Stilbenes; Superoxides

2012
Development of cardiac hypertrophy by sunitinib in vivo and in vitro rat cardiomyocytes is influenced by the aryl hydrocarbon receptor signaling pathway.
    Archives of toxicology, 2014, Volume: 88, Issue:3

    Topics: Animals; Cardiomegaly; Cell Survival; Cells, Cultured; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Enzymes; Gene Expression Regulation; Imidazoles; Indoles; Male; Myocytes, Cardiac; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptors, Aryl Hydrocarbon; Resveratrol; Signal Transduction; Stilbenes; Sunitinib

2014
Resveratrol attenuates matrix metalloproteinase-9 and -2-regulated differentiation of HTB94 chondrosarcoma cells through the p38 kinase and JNK pathways.
    Oncology reports, 2014, Volume: 32, Issue:1

    Topics: Anthracenes; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Cell Differentiation; Cell Line, Tumor; Chondrosarcoma; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Pyridines; Resveratrol; Stilbenes

2014
Regulation by resveratrol of prostaglandin E2-stimulated osteoprotegerin synthesis in osteoblasts.
    International journal of molecular medicine, 2014, Volume: 34, Issue:5

    Topics: 3T3 Cells; Animals; Anthracenes; Dinoprostone; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase 1; Osteoblasts; Osteoprotegerin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Resveratrol; Sirtuin 1; Stilbenes

2014
Down-regulation by resveratrol of basic fibroblast growth factor-stimulated osteoprotegerin synthesis through suppression of Akt in osteoblasts.
    International journal of molecular sciences, 2014, Oct-06, Volume: 15, Issue:10

    Topics: 3T3 Cells; Animals; Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Down-Regulation; Fibroblast Growth Factor 2; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteoblasts; Osteoprotegerin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Recombinant Proteins; Resveratrol; Stilbenes

2014
Resveratrol inhibits hyperglycemia-driven ROS-induced invasion and migration of pancreatic cancer cells via suppression of the ERK and p38 MAPK signaling pathways.
    International journal of oncology, 2016, Volume: 49, Issue:2

    Topics: Acetylcysteine; Cell Line, Tumor; Cell Movement; Diabetes Complications; Flavonoids; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Glucose; Humans; Hyperglycemia; Imidazoles; MAP Kinase Signaling System; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Pyridines; Reactive Oxygen Species; Resveratrol; Stilbenes

2016
Resveratrol Inhibits the Epidermal Growth Factor-Induced Migration of Osteoblasts: the Suppression of SAPK/JNK and Akt.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 43, Issue:3

    Topics: Animals; Anthracenes; Cell Movement; Cells, Cultured; Epidermal Growth Factor; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Resveratrol; rho-Associated Kinases; Sirtuin 1; Stilbenes

2017