Page last updated: 2024-09-05

sb 203580 and pyrimidine

sb 203580 has been researched along with pyrimidine in 2 studies

Compound Research Comparison

Studies (sb 203580)	Trials (sb 203580)	Recent Studies (post-2010) (sb 203580)	Studies (pyrimidine)	Trials (pyrimidine)	Recent Studies (post-2010) (pyrimidine)
3,489	4	1,137	2,159	6	950

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Di Sabatino, A; Docena, G; Fanning, A; Knowles, CH; Kruidenier, L; Leakey, NA; Lee, K; MacDonald, TT; McLean, PG; Nally, K; Rovedatti, L; Shanahan, F	1
Aoki, T; Arai, T; Hayashi, S; Hirokawa, H; Inoue, H; Kainoh, M; Kawai, H; Koga, Y; Meguro, H; Ohno, M; Oshida, K; Suyama, K	1

Other Studies

2 other study(ies) available for sb 203580 and pyrimidine

Article	Year
Down-regulation of p38 mitogen-activated protein kinase activation and proinflammatory cytokine production by mitogen-activated protein kinase inhibitors in inflammatory bowel disease. Clinical and experimental immunology, 2010, Volume: 162, Issue:1 Topics: Adolescent; Adult; Blotting, Western; Cells, Cultured; Cytokines; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Imidazoles; Inflammation Mediators; Inflammatory Bowel Diseases; Interleukin-1beta; Interleukin-6; Intestinal Mucosa; Male; Middle Aged; Niacinamide; Organ Culture Techniques; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Pyrimidines; Tumor Necrosis Factor-alpha; Young Adult	2010
Design and synthesis of novel p38α MAP kinase inhibitors: discovery of pyrazole-benzyl ureas bearing 2-molpholinopyrimidine moiety. Bioorganic & medicinal chemistry letters, 2012, Aug-01, Volume: 22, Issue:15 Topics: Administration, Oral; Animals; Binding Sites; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Drug Design; Drug Evaluation, Preclinical; Humans; Imidazoles; Lipopolysaccharides; Liver; Mice; Mitogen-Activated Protein Kinase 14; Naphthalenes; Protein Kinase Inhibitors; Protein Structure, Tertiary; Pyrazoles; Pyridines; Pyrimidines; Tumor Necrosis Factor-alpha; Urea	2012

Article

Year

Down-regulation of p38 mitogen-activated protein kinase activation and proinflammatory cytokine production by mitogen-activated protein kinase inhibitors in inflammatory bowel disease.

Clinical and experimental immunology, 2010, Volume: 162, Issue:1

Topics: Adolescent; Adult; Blotting, Western; Cells, Cultured; Cytokines; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Imidazoles; Inflammation Mediators; Inflammatory Bowel Diseases; Interleukin-1beta; Interleukin-6; Intestinal Mucosa; Male; Middle Aged; Niacinamide; Organ Culture Techniques; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Pyrimidines; Tumor Necrosis Factor-alpha; Young Adult

2010

Design and synthesis of novel p38α MAP kinase inhibitors: discovery of pyrazole-benzyl ureas bearing 2-molpholinopyrimidine moiety.

Bioorganic & medicinal chemistry letters, 2012, Aug-01, Volume: 22, Issue:15

Topics: Administration, Oral; Animals; Binding Sites; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Drug Design; Drug Evaluation, Preclinical; Humans; Imidazoles; Lipopolysaccharides; Liver; Mice; Mitogen-Activated Protein Kinase 14; Naphthalenes; Protein Kinase Inhibitors; Protein Structure, Tertiary; Pyrazoles; Pyridines; Pyrimidines; Tumor Necrosis Factor-alpha; Urea

2012