Page last updated: 2024-09-05

sb 203580 and pyridoxal phosphate

sb 203580 has been researched along with pyridoxal phosphate in 2 studies

Compound Research Comparison

Studies (sb 203580)	Trials (sb 203580)	Recent Studies (post-2010) (sb 203580)	Studies (pyridoxal phosphate)	Trials (pyridoxal phosphate)	Recent Studies (post-2010) (pyridoxal phosphate)
3,489	4	1,137	6,511	140	860

Protein Interaction Comparison

Protein	Taxonomy	sb 203580 (IC50)	pyridoxal phosphate (IC50)
P2X purinoceptor 1	Homo sapiens (human)		10

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Clay, WC; Condreay, JP; Hall, M; Holbrook, J; Livermore, D; Michel, AD; Ng, SW; Roman, S; Senger, S; Thompson, K	1
Csölle, C; Sperlágh, B	1

Other Studies

2 other study(ies) available for sb 203580 and pyridoxal phosphate

Article	Year
Identification of regions of the P2X(7) receptor that contribute to human and rat species differences in antagonist effects. British journal of pharmacology, 2008, Volume: 155, Issue:5 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Animals; Cell Line; Cloning, Molecular; Dose-Response Relationship, Drug; Glycine; Humans; Imidazoles; Molecular Sequence Data; Mutagenesis, Site-Directed; Piperazines; Plasmids; Polymorphism, Single Nucleotide; Protein Binding; Protein Structure, Tertiary; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridines; Pyridoxal Phosphate; Radioligand Assay; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Sequence Alignment; Species Specificity; Transfection	2008
Peripheral origin of IL-1beta production in the rodent hippocampus under in vivo systemic bacterial lipopolysaccharide (LPS) challenge and its regulation by P2X(7) receptors. Journal of neuroimmunology, 2010, Feb-26, Volume: 219, Issue:1-2 Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Hippocampus; Imidazoles; Interleukin-1beta; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Purinergic P2 Receptor Antagonists; Pyridines; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X7; RNA, Messenger; Xanthines	2010

Article

Year

Identification of regions of the P2X(7) receptor that contribute to human and rat species differences in antagonist effects.

British journal of pharmacology, 2008, Volume: 155, Issue:5

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Animals; Cell Line; Cloning, Molecular; Dose-Response Relationship, Drug; Glycine; Humans; Imidazoles; Molecular Sequence Data; Mutagenesis, Site-Directed; Piperazines; Plasmids; Polymorphism, Single Nucleotide; Protein Binding; Protein Structure, Tertiary; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridines; Pyridoxal Phosphate; Radioligand Assay; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Sequence Alignment; Species Specificity; Transfection

2008

Peripheral origin of IL-1beta production in the rodent hippocampus under in vivo systemic bacterial lipopolysaccharide (LPS) challenge and its regulation by P2X(7) receptors.

Journal of neuroimmunology, 2010, Feb-26, Volume: 219, Issue:1-2

Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Hippocampus; Imidazoles; Interleukin-1beta; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Purinergic P2 Receptor Antagonists; Pyridines; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X7; RNA, Messenger; Xanthines

2010