sb 203580 has been researched along with ps1145 in 4 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (ps1145) | Trials (ps1145) | Recent Studies (post-2010) (ps1145) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 54 | 1 | 25 |
| Protein | Taxonomy | sb 203580 (IC50) | ps1145 (IC50) |
|---|---|---|---|
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | 0.1646 | |
| Inhibitor of nuclear factor kappa-B kinase subunit alpha | Homo sapiens (human) | 0.1 | |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | 1.1 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.1 | |
| Serine/threonine-protein kinase pim-3 | Homo sapiens (human) | 0.88 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N | 1 |
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Chen, SU; Cheng, JC; Chou, CH | 1 |
| Baghdadi, M; Maekawa, R; Muto, M; Seino, K; Wada, H | 1 |
4 other study(ies) available for sb 203580 and ps1145
| Article | Year |
|---|---|
The selectivity of protein kinase inhibitors: a further update.
Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera | 2007 |
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Radiation-induced interleukin-6 expression through MAPK/p38/NF-kappaB signaling pathway and the resultant antiapoptotic effect on endothelial cells through Mcl-1 expression with sIL6-Ralpha.
Topics: Apoptosis; Cell Survival; Dose-Response Relationship, Radiation; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression; Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; Interleukin-6; Mitogen-Activated Protein Kinases; Myeloid Cell Leukemia Sequence 1 Protein; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Pyridines; Receptors, Interleukin-6; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Transcription Factor AP-1 | 2009 |
Myeloid molecular characteristics of human γδ T cells support their acquisition of tumor antigen-presenting capacity.
Topics: Antigen Presentation; Antigens, Neoplasm; CCAAT-Enhancer-Binding Proteins; CD36 Antigens; CD8-Positive T-Lymphocytes; Cell Differentiation; Cell Line, Tumor; Cell Lineage; Cytotoxicity, Immunologic; Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; Immunotherapy; Lymphocyte Activation; MART-1 Antigen; Myeloid Cells; Neoplasms; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phagocytosis; Pyridines; Receptors, Antigen, T-Cell, gamma-delta; Signal Transduction; T-Lymphocytes; Up-Regulation | 2015 |