Compounds > sb 203580
Page last updated: 2024-09-05

sb 203580 and olomoucine

sb 203580 has been researched along with olomoucine in 6 studies

Compound Research Comparison

Studies
(sb 203580)		Trials
(sb 203580)		Recent Studies (post-2010)
(sb 203580)		Studies
(olomoucine)		Trials
(olomoucine)		Recent Studies (post-2010) (olomoucine)
3,48941,137227024

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)olomoucine (IC50)
Chain A, MAP KINASE P38Homo sapiens (human)27
Chain A, PROTEIN (MAP KINASE P38)Homo sapiens (human)27
Chain A, PROTEIN (MAP KINASE P38)Homo sapiens (human)27
Chain A, Protein (map Kinase P38)Homo sapiens (human)27
Chain A, Extracellular Regulated Kinase 2Rattus norvegicus (Norway rat)27
Chain A, Extracellular Regulated Kinase 2Rattus norvegicus (Norway rat)27
G2/mitotic-specific cyclin-B2Homo sapiens (human)7
G1/S-specific cyclin-E2Homo sapiens (human)7.8
Tyrosine-protein kinase LckHomo sapiens (human)7
Cyclin-dependent kinase 1Homo sapiens (human)6.7875
Cyclin-dependent kinase 4Homo sapiens (human)7
G2/mitotic-specific cyclin-B1Homo sapiens (human)7
G2/mitotic-specific cyclin-BMarthasterias glacialis (spiny starfish)5.2571
Cyclin-A2Homo sapiens (human)7.75
G1/S-specific cyclin-D1Homo sapiens (human)7
G1/S-specific cyclin-E1Homo sapiens (human)6.4436
Cyclin-dependent kinase 2Homo sapiens (human)6.5945
Mitogen-activated protein kinase 1Homo sapiens (human)7
Vascular endothelial growth factor receptor 2Homo sapiens (human)7
Cyclin-A1Homo sapiens (human)7.75
Cyclin-dependent-like kinase 5 Homo sapiens (human)4.6
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)5.6667
G2/mitotic-specific cyclin-B3Homo sapiens (human)7
Cyclin-dependent kinase 1Oryzias latipes (Japanese medaka)5.2571

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Abdel-Meguid, S; Adams, JL; Boehm, JC; Canagarajah, BJ; Cobb, MH; Goldsmith, EJ; Kassisà, S; Wang, Z; Young, PR1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB1
Bharate, SB; Raghuvanshi, R1
Cheng, TJ; Lai, YK1
Bian, H; Chellappan, SP; Nath, N; Reed, EF1

Other Studies

6 other study(ies) available for sb 203580 and olomoucine

ArticleYear
Structural basis of inhibitor selectivity in MAP kinases.
    Structure (London, England : 1993), 1998, Sep-15, Volume: 6, Issue:9

    Topics: Adenosine Triphosphate; Calcium-Calmodulin-Dependent Protein Kinases; Catalytic Domain; Cell Differentiation; Cell Division; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Imidazoles; Kinetin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Models, Chemical; Models, Molecular; p38 Mitogen-Activated Protein Kinases; Protein Conformation; Purines; Pyridines; Pyrimidines; Structure-Activity Relationship

1998
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
Navigating the kinome.
    Nature chemical biology, 2011, Volume: 7, Issue:4

    Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology

2011
Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Drug Approval; Drug Repositioning; High-Throughput Screening Assays; Humans; Protein Kinase Inhibitors; SARS-CoV-2; United States; United States Food and Drug Administration; Virus Diseases

2022
Identification of mitogen-activated protein kinase-activated protein kinase-2 as a vimentin kinase activated by okadaic acid in 9L rat brain tumor cells.
    Journal of cellular biochemistry, 1998, Nov-01, Volume: 71, Issue:2

    Topics: Animals; Brain Neoplasms; Cytosol; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Gliosarcoma; Imidazoles; Intracellular Signaling Peptides and Proteins; Kinetin; Okadaic Acid; Peptide Mapping; Phosphorylation; Protein Serine-Threonine Kinases; Purines; Pyridines; Rats; Tumor Cells, Cultured

1998
HLA class I-mediated induction of cell proliferation involves cyclin E-mediated inactivation of Rb function and induction of E2F activity.
    Journal of immunology (Baltimore, Md. : 1950), 1999, May-01, Volume: 162, Issue:9

    Topics: Carrier Proteins; Cell Cycle Proteins; Cell Division; Cells, Cultured; Cyclin E; Cyclin-Dependent Kinases; DNA-Binding Proteins; E2F Transcription Factors; Endothelium, Vascular; Enzyme Activation; fas Receptor; Growth Inhibitors; Histocompatibility Antigens Class I; HLA Antigens; Humans; Imidazoles; Jurkat Cells; Kinetin; Purines; Pyridines; Receptors, Fibroblast Growth Factor; Retinoblastoma Protein; Retinoblastoma-Binding Protein 1; Signal Transduction; T-Lymphocytes; Transcription Factor DP1; Transcription Factors

1999