sb 203580 has been researched along with okadaic acid in 20 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (okadaic acid) | Trials (okadaic acid) | Recent Studies (post-2010) (okadaic acid) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 3,865 | 2 | 658 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (30.00) | 18.2507 |
| 2000's | 13 (65.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cano, E; Cohen, P; Cuenda, A; Hazzalin, CA; Mahadevan, LC | 1 |
| Chang, MD; Chang, YN; Chen, KD; Chen, LY; Huang, HL; Lai, YK; Lieu, CH | 1 |
| Cheng, TJ; Lai, YK | 1 |
| Ahonen, M; Eriksson, JE; Holmström, T; Kähäri, VM; Westermarck, J | 1 |
| Burns, CJ; Howell, SL; Jones, PM; Persaud, SJ | 1 |
| Bowden, GT; Gupta, A; Rosenberger, SF | 1 |
| Chen, KD; Chen, LY; Cho, JH; Lai, MT; Lai, YK | 1 |
| Birkenkamp, KU; Kruijer, W; Lummen, C; Tuyt, LM; Vellenga, E; Wierenga, AT | 1 |
| Lee, J; Mira-Arbibe, L; Ulevitch, RJ | 1 |
| Gimbrone, MA; Masuda, J; Ochi, H | 1 |
| Grewal, S; Morrison, EE; Ponnambalam, S; Walker, JH | 1 |
| Broome, AM; Eckert, RL; Efimova, T | 1 |
| Griendling, KK; Rocic, P; Seshiah, P | 1 |
| Chaves, AC; Closel, M; Gazzinelli, RT; Ropert, C | 1 |
| Andreka, P; Bishopric, NH; Evans, WH; Haywood, GA; Martin, PE; Turner, MS; Webster, KA; You, L | 1 |
| Hoffmann, EK; Marshall, WS; Ossum, CG | 1 |
| Martín, ME; O'Loghlen, A; Pérez-Morgado, MI; Salinas, M | 1 |
| Casarini, L; Malagoli, D; Ottaviani, E | 1 |
| Babo, I; Harisi, R; Jeney, A; Kenessey, I; Olah, JN; Paku, S; Pogany, G; Timar, F | 1 |
| Agrawal, M; Bala Bhaskar, AS; Gupta, N; Lakshmana Rao, PV; Ravindran, J | 1 |
20 other study(ies) available for sb 203580 and okadaic acid
| Article | Year |
|---|---|
Effects of the inhibition of p38/RK MAP kinase on induction of five fos and jun genes by diverse stimuli.
Topics: Animals; Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; Gene Expression Regulation; Genes, fos; Genes, jun; Imidazoles; Mice; Okadaic Acid; Pyridines; Transcriptional Activation; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 1997 |
Involvement of p38 mitogen-activated protein kinase signaling pathway in the rapid induction of the 78-kDa glucose-regulated protein in 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cyclic AMP-Dependent Protein Kinases; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Heat-Shock Proteins; Imidazoles; Mitogen-Activated Protein Kinases; Molecular Chaperones; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Pyridines; Rats; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured | 1998 |
Identification of mitogen-activated protein kinase-activated protein kinase-2 as a vimentin kinase activated by okadaic acid in 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Cytosol; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Gliosarcoma; Imidazoles; Intracellular Signaling Peptides and Proteins; Kinetin; Okadaic Acid; Peptide Mapping; Phosphorylation; Protein Serine-Threonine Kinases; Purines; Pyridines; Rats; Tumor Cells, Cultured | 1998 |
Enhancement of fibroblast collagenase-1 (MMP-1) gene expression by tumor promoter okadaic acid is mediated by stress-activated protein kinases Jun N-terminal kinase and p38.
Topics: 3T3 Cells; Adult; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cells, Cultured; Collagenases; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Matrix Metalloproteinase 1; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines | 1998 |
The p38 mitogen-activated protein kinase cascade is not required for the stimulation of insulin secretion from rat islets of Langerhans.
Topics: Animals; Arsenites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cells, Cultured; Colforsin; Enzyme Inhibitors; Glucose; Homeostasis; Imidazoles; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Mitogen-Activated Protein Kinases; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Compounds; Sorbitol; Tetradecanoylphorbol Acetate; Vanadates | 1999 |
Inhibition of p38 MAP kinase increases okadaic acid mediated AP-1 expression and DNA binding but has no effect on TRE dependent transcription.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Consensus Sequence; DNA; DNA-Binding Proteins; Enzyme Activation; Imidazoles; JNK Mitogen-Activated Protein Kinases; Keratinocytes; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Protein Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyridines; Response Elements; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation | 1999 |
Activation of p38 mitogen-activated protein kinase and mitochondrial Ca(2+)-mediated oxidative stress are essential for the enhanced expression of grp78 induced by the protein phosphatase inhibitors okadaic acid and calyculin A.
Topics: Acetylcysteine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Egtazic Acid; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Heat-Shock Proteins; Imidazoles; Marine Toxins; Mitochondria; Mitogen-Activated Protein Kinases; Molecular Chaperones; Okadaic Acid; Oxazoles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Proline; Promoter Regions, Genetic; Pyridines; Rats; RNA, Messenger; Ruthenium Red; Thiocarbamates; Transcriptional Activation; Tumor Cells, Cultured | 2000 |
The p38 MAP kinase inhibitor SB203580 enhances nuclear factor-kappa B transcriptional activity by a non-specific effect upon the ERK pathway.
Topics: DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Imidazoles; MAP Kinase Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; Pyridines; Transcriptional Activation; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
TAK1 regulates multiple protein kinase cascades activated by bacterial lipopolysaccharide.
Topics: Androstadienes; Animals; Apoptosis; Cell Line; Chromones; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Hydrogen Peroxide; Hypertonic Solutions; I-kappa B Kinase; Imidazoles; Inflammation; Insulin-Like Growth Factor I; Interleukin-1; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Morpholines; NF-kappa B; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Prostaglandins A; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Recombinant Fusion Proteins; Signal Transduction; Stress, Physiological; Transfection; Tumor Cells, Cultured; Wortmannin | 2000 |
Hyperosmotic stimuli inhibit VCAM-1 expression in cultured endothelial cells via effects on interferon regulatory factor-1 expression and activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Membrane; Cells, Cultured; Culture Media; Cycloheximide; DNA-Binding Proteins; E-Selectin; Endothelium, Vascular; Gene Expression Regulation; GTP-Binding Proteins; Imidazoles; Intercellular Adhesion Molecule-1; Interferon Regulatory Factor-1; Interferon-gamma; Interferon-Stimulated Gene Factor 3; Interleukin-1; Interleukin-13; Interleukin-4; NF-kappa B; Okadaic Acid; Osmosis; Phosphoproteins; Promoter Regions, Genetic; Pyridines; RNA, Messenger; Staurosporine; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2002 |
Nuclear localisation of cytosolic phospholipase A2-alpha in the EA.hy.926 human endothelial cell line is proliferation dependent and modulated by phosphorylation.
Topics: Amino Acid Sequence; Cell Count; Cell Division; Cell Line; Cell Nucleus; Cytosol; Fatty Acids, Unsaturated; Flavonoids; Gene Expression Regulation, Enzymologic; Group IV Phospholipases A2; Humans; Imidazoles; Lectins; Models, Molecular; Molecular Sequence Data; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Conformation; Protein Transport; Pyridines; Staurosporine | 2002 |
A regulatory role for p38 delta MAPK in keratinocyte differentiation. Evidence for p38 delta-ERK1/2 complex formation.
Topics: Adenoviridae; Cell Differentiation; Cells, Cultured; Enzyme Inhibitors; Epidermal Cells; Genes, Dominant; HeLa Cells; Humans; Imidazoles; Keratinocytes; Luciferases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 13; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Okadaic Acid; Plasmids; Promoter Regions, Genetic; Protein Binding; Protein Isoforms; Protein Precursors; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transfection | 2003 |
Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells.
Topics: Acetylcysteine; Angiotensin II; Animals; Aorta; Azoles; Blotting, Western; Carrier Proteins; Cells, Cultured; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Genes, Dominant; Imidazoles; Intracellular Signaling Peptides and Proteins; Isoindoles; Muscle, Smooth, Vascular; Okadaic Acid; Onium Compounds; Organoselenium Compounds; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Protein Phosphatase 2; Pyridines; Rats; Reactive Oxygen Species; Serine; Threonine; Time Factors | 2003 |
Inhibition of a p38/stress-activated protein kinase-2-dependent phosphatase restores function of IL-1 receptor-associate kinase-1 and reverses Toll-like receptor 2- and 4-dependent tolerance of macrophages.
Topics: Animals; CHO Cells; Cricetinae; Enzyme Activation; Flavonoids; Gene Expression; Glycosylphosphatidylinositols; I-kappa B Kinase; Imidazoles; Immune Tolerance; Interleukin-1 Receptor-Associated Kinases; Lipopolysaccharides; Macrophages, Peritoneal; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Mucins; NF-kappa B; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; Receptors, Cell Surface; Recombinant Proteins; Signal Transduction; Toll-Like Receptor 2; Toll-Like Receptor 4; Toll-Like Receptors; Trypanosoma cruzi; Tumor Necrosis Factor-alpha | 2003 |
Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels.
Topics: Adenosine Triphosphate; Alkaloids; Aminoimidazole Carboxamide; Animals; Antimycin A; Benzophenanthridines; Brefeldin A; Carbazoles; Cell Hypoxia; Cells, Cultured; Connexin 43; Cycloheximide; Deoxyglucose; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Myocardial Contraction; Myocytes, Cardiac; Okadaic Acid; Ouabain; Phenanthridines; Phosphorylation; Potassium Cyanide; Protein Processing, Post-Translational; Pyridines; Pyrroles; Rats; Recombinant Fusion Proteins; Ribonucleotides; Staurosporine; Tacrolimus; Tetradecanoylphorbol Acetate | 2004 |
Hypotonic shock mediation by p38 MAPK, JNK, PKC, FAK, OSR1 and SPAK in osmosensing chloride secreting cells of killifish opercular epithelium.
Topics: Alkaloids; Animals; Benzophenanthridines; Blotting, Western; Chlorides; Cyclic AMP-Dependent Protein Kinases; Electrophoresis, Polyacrylamide Gel; Electrophysiology; Epithelium; Focal Adhesion Protein-Tyrosine Kinases; Fundulidae; Imidazoles; Immunohistochemistry; Ion Channels; Isoquinolines; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Nova Scotia; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phenanthridines; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; Saline Solution, Hypertonic; Sulfonamides; Tamoxifen; Water-Electrolyte Balance | 2005 |
N-acetyl-cysteine abolishes hydrogen peroxide-induced modification of eukaryotic initiation factor 4F activity via distinct signalling pathways.
Topics: Acetylcysteine; Animals; Carrier Proteins; Eukaryotic Initiation Factor-4F; Eukaryotic Initiation Factor-4G; Hydrogen Peroxide; Imidazoles; Intracellular Signaling Peptides and Proteins; Okadaic Acid; PC12 Cells; Phosphoproteins; Pyridines; Rats; Signal Transduction; Sirolimus | 2006 |
Effects of the marine toxins okadaic acid and palytoxin on mussel phagocytosis.
Topics: Acrylamides; Animals; Antibodies; Cnidarian Venoms; Enzyme Inhibitors; Flavonoids; Imidazoles; Immunoblotting; Marine Toxins; Mytilus; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phagocytosis; Pyridines; Temperature | 2008 |
Differential inhibition of single and cluster type tumor cell migration.
Topics: Adolescent; Bone Neoplasms; Cell Culture Techniques; Cell Movement; Cell Proliferation; Chromones; Deoxyuridine; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibrosarcoma; Flavonoids; Humans; Imidazoles; Male; Morpholines; Okadaic Acid; Osteosarcoma; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Signal Transduction; Tumor Cells, Cultured | 2009 |
Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Anthracenes; Apoptosis; Apoptosis Inducing Factor; Blotting, Western; Caspase 3; Caspase 7; Caspase 9; Cell Line, Tumor; Cyclosporins; Cytochromes c; DNA Damage; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glutathione; Humans; Imidazoles; Immunoblotting; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Pyridines; Reactive Oxygen Species; U937 Cells | 2011 |