sb 203580 has been researched along with n-methylaspartate in 11 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (n-methylaspartate) | Trials (n-methylaspartate) | Recent Studies (post-2010) (n-methylaspartate) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 10,408 | 59 | 1,902 |
| Protein | Taxonomy | sb 203580 (IC50) | n-methylaspartate (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 5.175 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coogan, AN; O'Connor, JJ | 1 |
| Cruise, L; Fuller, G; Ho, LK; Morris, BJ; Veitch, K | 2 |
| Clark, CJ; Morris, BJ; O'shaughnessy, CT; Rakhit, S | 1 |
| Desai, MK; Kaul, M; Lipton, SA; Ma, Q; Medders, KE | 1 |
| Katayama, T; Minami, M; Tanaka, H; Uehara, T; Yoshida, T | 1 |
| Chen, Y; Feng, C; Xiao, L | 1 |
| Armstead, WM; Cines, DB; Higazi, AA; Kiessling, JW; Riley, J | 1 |
| Qin, HP; Si, PP; Sun, P; Sun, XF; Yang, XR; Zhang, C | 1 |
| He, P; Ji, EF; Li, XD; Liu, XW; Tian, BX; Xing, RX | 1 |
| Beitz, AJ; Kaang, BK; Kim, YH; Ko, HG; Kwon, SG; Lee, JH; Oh, SB; Roh, DH; Yeo, JH; Yoon, SY | 1 |
11 other study(ies) available for sb 203580 and n-methylaspartate
| Article | Year |
|---|---|
Interleukin-1beta inhibits a tetraethylammonium-induced synaptic potentiation in the rat dentate gyrus in vitro.
Topics: Animals; Dentate Gyrus; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Humans; Imidazoles; In Vitro Techniques; Interleukin-1; Long-Term Potentiation; Male; N-Methylaspartate; Potassium Channel Blockers; Pyridines; Rats; Rats, Wistar; Tetraethylammonium; Time Factors | 1999 |
Kainate receptors activate NF-kappaB via MAP kinase in striatal neurones.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcimycin; Calcium; Cells, Cultured; Corpus Striatum; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; Imidazoles; Immunohistochemistry; In Vitro Techniques; Ionophores; Kainic Acid; Mitogen-Activated Protein Kinases; N-Methylaspartate; Neurons; NF-kappa B; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Transcription Factor RelA | 2000 |
Activation of p44/p42 MAP kinase in striatal neurons via kainate receptors and PI3 kinase.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Androstadienes; Animals; Corpus Striatum; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; Kainic Acid; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; N-Methylaspartate; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Wortmannin | 2001 |
N-methyl-D-aspartate and brain-derived neurotrophic factor induce distinct profiles of extracellular signal-regulated kinase, mitogen- and stress-activated kinase, and ribosomal s6 kinase phosphorylation in cortical neurons.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Imidazoles; N-Methylaspartate; Phosphorylation; Pyridines; Rats; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa | 2005 |
HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection.
Topics: Animals; Cell Death; Chemokine CXCL12; Cytokines; HIV Envelope Protein gp120; HIV Infections; HIV-1; Imidazoles; Ligands; Mice; Mice, Inbred C57BL; Models, Immunological; N-Methylaspartate; Neuroglia; Neurons; Neurotoxins; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Receptors, CCR5; Receptors, CXCR4 | 2007 |
Neuronal injury induces cytokine-induced neutrophil chemoattractant-1 (CINC-1) production in astrocytes.
Topics: Animals; Anthracenes; Astrocytes; Butadienes; Cells, Cultured; Cerebral Cortex; Chemokine CXCL1; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Imidazoles; Immunochemistry; Mitogen-Activated Protein Kinases; N-Methylaspartate; Neurons; Nitriles; Pyridines; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2009 |
Glucocorticoid rapidly enhances NMDA-evoked neurotoxicity by attenuating the NR2A-containing NMDA receptor-mediated ERK1/2 activation.
Topics: Animals; Blotting, Western; Calcium; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Glucocorticoids; Hippocampus; Imidazoles; Mifepristone; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; N-Methylaspartate; Neurons; p38 Mitogen-Activated Protein Kinases; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2010 |
tPA contributes to impaired NMDA cerebrovasodilation after traumatic brain injury through activation of JNK MAPK.
Topics: Animals; Animals, Newborn; Anthracenes; Brain Injuries; Butadienes; Drug Interactions; Female; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; N-Methylaspartate; Nitriles; Oligopeptides; Papaverine; Peptides; Pia Mater; Pyridines; Swine; Tissue Plasminogen Activator; Up-Regulation; Vasoconstriction; Vasodilation | 2011 |
Involvement of MAPK pathways in NMDA-induced apoptosis of rat cortical neurons.
Topics: Animals; Anthracenes; Apoptosis; Caspase 3; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; N-Methylaspartate; Neurons; p38 Mitogen-Activated Protein Kinases; Primary Cell Culture; Pyridines; Rats | 2012 |
Protective effects of the p38 MAPK inhibitor SB203580 on NMDA‑induced injury in primary cerebral cortical neurons.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Survival; Cells, Cultured; Cerebral Cortex; Imidazoles; Immunohistochemistry; N-Methylaspartate; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Pyridines; Rats; Rats, Sprague-Dawley | 2014 |
A critical role of spinal Shank2 proteins in NMDA-induced pain hypersensitivity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Flavonoids; Hyperalgesia; Imidazoles; MAP Kinase Signaling System; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Nerve Tissue Proteins; Nociception; Pain; Pain Measurement; Protein Kinase Inhibitors; Pyridines; Spinal Cord | 2017 |