sb 203580 has been researched along with ml 3403 in 4 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (ml 3403) | Trials (ml 3403) | Recent Studies (post-2010) (ml 3403) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 5 | 0 | 2 |
| Protein | Taxonomy | sb 203580 (IC50) | ml 3403 (IC50) |
|---|---|---|---|
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | 0.8538 | |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | 0.8538 | |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | 0.8538 | |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | 0.7748 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Albrecht, W; Kotschenreuther, DA; Laufer, SA; Wagner, GK | 1 |
| Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M | 1 |
| Domeyer, DM; Hauser, DR; Kinkel, K; Laufer, SA; Liedtke, AJ | 1 |
| Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A | 1 |
4 other study(ies) available for sb 203580 and ml 3403
| Article | Year |
|---|---|
Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes.
Topics: Aminopyridines; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Cytochrome P-450 Enzyme System; Cytokines; Enzyme Inhibitors; Humans; Imidazoles; Interleukin-1; Isoenzymes; Leukocytes, Mononuclear; Liver; Mitogen-Activated Protein Kinases; Models, Molecular; p38 Mitogen-Activated Protein Kinases; Pyridines; Stereoisomerism; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2003 |
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases | 2007 |
Design, synthesis, and biological evaluation of novel Tri- and tetrasubstituted imidazoles as highly potent and specific ATP-mimetic inhibitors of p38 MAP kinase: focus on optimized interactions with the enzyme's surface-exposed front region.
Topics: Drug Design; Humans; Imidazoles; Molecular Mimicry; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Structure-Activity Relationship | 2008 |
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase | 2013 |