Page last updated: 2024-09-05

sb 203580 and losartan potassium

sb 203580 has been researched along with losartan potassium in 6 studies

Compound Research Comparison

Studies
(sb 203580)
Trials
(sb 203580)
Recent Studies (post-2010)
(sb 203580)
Studies
(losartan potassium)
Trials
(losartan potassium)
Recent Studies (post-2010) (losartan potassium)
3,48941,13724,3902,4935,408

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)losartan potassium (IC50)
Bile salt export pumpHomo sapiens (human)8.53
Type-1A angiotensin II receptor Rattus norvegicus (Norway rat)0.0082
Type-1B angiotensin II receptorRattus norvegicus (Norway rat)0.0049
Type-2 angiotensin II receptorRattus norvegicus (Norway rat)0.0082
5-hydroxytryptamine receptor 1AMus musculus (house mouse)0.0082
Type-1 angiotensin II receptorCavia porcellus (domestic guinea pig)0.018

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bittorf, T; Kósa, F; Magócsi, M; Marotzki, S; Marquardt, H; Ramirez-Chávez, Y; Rosche, A; Schaefer, A1
Du, F; Gong, Q; Ke, Y; Qian, ZM; Wu, XM; Yung, WH; Zhu, L1
Kambe, T; Kim, WJ; Moon, SK; Nagao, M; Park, SL; Song, JH; Won, SY1
Agafonov, VI; Chaikovskii, AV; Dygai, AM; Khrichkova, TY; Minakova, MY; Miroshnichenko, LA; Sherstoboev, EY; Simanina, EV; Stavrova, LA; Udut, EV; Zhdanov, VV; Zyuz'kov, GN1
Hong, L; Huang, Z; Li, H; Miao, B; Na, N; Zhang, J; Zhao, D1
Duan, Y; Jin, Z; Song, Y; Wang, L; Wu, F1

Other Studies

6 other study(ies) available for sb 203580 and losartan potassium

ArticleYear
Opposite effects of inhibitors of mitogen-activated protein kinase pathways on the egr-1 and beta-globin expression in erythropoietin-responsive murine erythroleukemia cells.
    Cellular signalling, 2004, Volume: 16, Issue:2

    Topics: Animals; Butadienes; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Inhibitors; Erythropoietin; Flavonoids; Gene Expression Regulation, Neoplastic; Globins; Imidazoles; Immediate-Early Proteins; Leukemia, Erythroblastic, Acute; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Proto-Oncogene Proteins c-fos; Pyridines; Transcription Factors; Tumor Cells, Cultured

2004
Neuroprotective effect of ligustilide against ischaemia-reperfusion injury via up-regulation of erythropoietin and down-regulation of RTP801.
    British journal of pharmacology, 2011, Volume: 164, Issue:2

    Topics: 4-Butyrolactone; Animals; Cell Line; Chromones; Erythropoietin; Flavonoids; Gene Expression Regulation; Glucose; Imidazoles; L-Lactate Dehydrogenase; Male; Morpholines; Neurons; Oxygen; Plasmids; Pyridines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Repressor Proteins; Transcription Factors

2011
EPO gene expression promotes proliferation, migration and invasion via the p38MAPK/AP-1/MMP-9 pathway by p21WAF1 expression in vascular smooth muscle cells.
    Cellular signalling, 2015, Volume: 27, Issue:3

    Topics: Cell Cycle Proteins; Cell Line; Cell Movement; Cell Proliferation; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Down-Regulation; Erythropoietin; Humans; Imidazoles; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Smooth Muscle; NF-kappa B; Oncogene Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; RNA Interference; RNA, Small Interfering; Transcription Factor AP-1

2015
Role of PI3K, MAPK/ERK 1/2, and p38 in Production of Erythropoietic Activity by Bone Marrow Cells after Blood Loss.
    Bulletin of experimental biology and medicine, 2016, Volume: 162, Issue:1

    Topics: Anemia; Animals; Bone Marrow Cells; Chromones; Disease Models, Animal; Erythropoiesis; Erythropoietin; Flavonoids; Gene Expression Regulation; Hemorrhage; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Pyridines; Signal Transduction

2016
Renoprotective effect of erythropoietin via modulation of the STAT6/MAPK/NF-κB pathway in ischemia/reperfusion injury after renal transplantation.
    International journal of molecular medicine, 2018, Volume: 41, Issue:1

    Topics: Acetylcysteine; Animals; Anthracenes; Apoptosis; Erythropoietin; Gene Expression Regulation; Humans; Imidazoles; Interferon-gamma; Kidney; Kidney Transplantation; Lentivirus; MAP Kinase Kinase 4; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrimidines; Rats; Reperfusion Injury; RNA, Small Interfering; Signal Transduction; STAT6 Transcription Factor

2018
Erythropoietin induces the osteogenesis of periodontal mesenchymal stem cells from healthy and periodontitis sources via activation of the p38 MAPK pathway.
    International journal of molecular medicine, 2018, Volume: 41, Issue:2

    Topics: Adult; Cell Differentiation; Cell Proliferation; Erythropoietin; Female; Humans; Imidazoles; Male; Mesenchymal Stem Cells; Middle Aged; Osteogenesis; p38 Mitogen-Activated Protein Kinases; Periodontal Ligament; Periodontitis; Primary Cell Culture; Pyridines; Signal Transduction

2018