sb 203580 has been researched along with leptin in 16 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (leptin) | Trials (leptin) | Recent Studies (post-2010) (leptin) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 25,940 | 1,628 | 11,468 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (75.00) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duan, J; Norby, FL; Relling, DP; Ren, J; Wold, LE | 1 |
| Finck, BN; Johnson, RW | 1 |
| Eggo, MC; Holder, JC; Kumar, S; Patel, NG; Smith, SA | 1 |
| Gan, XT; Karmazyn, M; Kirshenbaum, LA; Rajapurohitam, V | 1 |
| Aberle, NS; Hintz, KK; Ren, J | 1 |
| De Girolamo, S; Li, RK; Madani, S; Muñoz, DM; Sweeney, G | 1 |
| Feng, J; Fried, SK; Greenberg, AS; Lee, MJ; Schneider, SH; Sullivan, S; Trujillo, ME | 1 |
| Hou, M; Ling, W; Ma, J; Tang, Z; Wang, Q; Xia, M; Xiao, Y; Zhao, T; Zhu, H | 1 |
| Cao, Q; Lieber, CS; Mak, KM | 1 |
| Gómez, R; Gomez-Reino, JJ; Gualillo, O; Lago, F; Lago, R; Otero, M | 1 |
| Ceylan-Isik, AF; Esberg, LB; Relling, DP; Ren, J; Zhu, BH | 1 |
| Bruno, A; Chanez, P; Chiappara, G; Gerbino, S; Gjomarkaj, M; Gras, D; La Guardia, M; Pace, E; Profita, M; Vachier, I | 1 |
| Adeli, K; Bandsma, RH; Lewis, GF; Naples, M; Xi, L; Xiao, C | 1 |
| Deng, Z; Liang, C; Liao, J; Song, C; Tavernier, J; Xue, H; Yan, G; Zabeau, L; Zhang, J; Zhang, K | 1 |
| Choi, SK; Choi, Y; Moon, HS; Park, S | 1 |
| Chen, J; Cheng, F; Feng, J; Lan, J; Lei, Y; Mei, W; Xu, Q; Zeng, B; Zhai, Y; Zhang, W; Zhen, Y; Zheng, D | 1 |
16 other study(ies) available for sb 203580 and leptin
| Article | Year |
|---|---|
Abrogated leptin-induced cardiac contractile response in ventricular myocytes under spontaneous hypertension: role of Jak/STAT pathway.
Topics: Animals; Blood Pressure; Calcium; Carrier Proteins; Cell Size; DNA-Binding Proteins; Enzyme Inhibitors; Heart Ventricles; Hypertension; Imidazoles; Janus Kinase 2; Leptin; Mitogen-Activated Protein Kinase Kinases; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Cell Surface; Receptors, Leptin; Signal Transduction; STAT3 Transcription Factor; Trans-Activators; Tyrphostins; Ventricular Dysfunction, Left | 2002 |
Anti-inflammatory agents inhibit the induction of leptin by tumor necrosis factor-alpha.
Topics: Adipose Tissue; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Culture Techniques; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Homeostasis; Imidazoles; Immunologic Factors; Leptin; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mitogen-Activated Protein Kinases; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Prostaglandin D2; Protein Synthesis Inhibitors; Pyridines; RNA, Messenger; Tumor Necrosis Factor-alpha | 2002 |
Differential regulation of lipogenesis and leptin production by independent signaling pathways and rosiglitazone during human adipocyte differentiation.
Topics: Adipocytes; Androstadienes; Cell Differentiation; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Leptin; Lipid Metabolism; Lipids; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines; Rosiglitazone; Signal Transduction; Sirolimus; Stem Cells; Thiazoles; Thiazolidinediones; Tumor Necrosis Factor-alpha; Wortmannin | 2003 |
The obesity-associated peptide leptin induces hypertrophy in neonatal rat ventricular myocytes.
Topics: Animals; Animals, Newborn; Blotting, Western; Cell Size; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Heart Ventricles; Imidazoles; Leptin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Obesity; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Receptors, Cell Surface; Receptors, Leptin; RNA, Messenger | 2003 |
Insulin resistance induces hyperleptinemia, cardiac contractile dysfunction but not cardiac leptin resistance in ventricular myocytes.
Topics: Animals; Blood Glucose; Calcium; Enzyme Inhibitors; Glucose Tolerance Test; Imidazoles; Insulin Resistance; Leptin; Male; Myocardial Contraction; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Pyridines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Tyrphostins; Ventricular Function | 2003 |
Direct effects of leptin on size and extracellular matrix components of human pediatric ventricular myocytes.
Topics: Cell Size; Cells, Cultured; Extracellular Matrix Proteins; Flavonoids; Heart Ventricles; Humans; Imidazoles; Infant; Janus Kinase 1; Leptin; Microscopy, Phase-Contrast; Mitogen-Activated Protein Kinase Kinases; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Tyrphostins | 2006 |
Tumor necrosis factor alpha and glucocorticoid synergistically increase leptin production in human adipose tissue: role for p38 mitogen-activated protein kinase.
Topics: Adipocytes; Adipose Tissue; Adult; Cell Size; Cells, Cultured; Cytokines; Dexamethasone; Drug Synergism; Enzyme Inhibitors; Female; Gene Expression Regulation; Glucocorticoids; Humans; Imidazoles; Leptin; Mitogen-Activated Protein Kinase 1; Obesity; p38 Mitogen-Activated Protein Kinases; Pyridines; RNA, Messenger; Signal Transduction; Stimulation, Chemical; Tumor Necrosis Factor-alpha | 2006 |
Globular adiponectin decreases leptin-induced tumor necrosis factor-alpha expression by murine macrophages: involvement of cAMP-PKA and MAPK pathways.
Topics: Adiponectin; Animals; Butadienes; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Enzyme Activation; Flavonoids; Imidazoles; Isoquinolines; Leptin; Macrophages, Peritoneal; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 3; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Tumor Necrosis Factor-alpha | 2005 |
Leptin represses matrix metalloproteinase-1 gene expression in LX2 human hepatic stellate cells.
Topics: Base Sequence; Catalase; Cell Line; Down-Regulation; Enzyme Inhibitors; Hepatocytes; Humans; Hydrogen Peroxide; Imidazoles; Janus Kinases; Leptin; Liver Cirrhosis; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Models, Biological; Oligodeoxyribonucleotides, Antisense; Pyridines; RNA, Messenger; STAT3 Transcription Factor; STAT5 Transcription Factor; Tyrphostins | 2007 |
Phosphatidylinositol 3-kinase, MEK-1 and p38 mediate leptin/interferon-gamma synergistic NOS type II induction in chondrocytes.
Topics: Androstadienes; Animals; Blotting, Western; Cell Line; Cells, Cultured; Chondrocytes; Chromones; Enzyme Induction; Enzyme Inhibitors; Enzymes; Flavonoids; Humans; Imidazoles; Interferon-gamma; Leptin; MAP Kinase Kinase 1; Morpholines; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Wortmannin | 2007 |
High-fat diet-induced obesity leads to resistance to leptin-induced cardiomyocyte contractile response.
Topics: Animals; Calcium; Cells, Cultured; Diet, Fat-Restricted; Dietary Fats; Enzyme Inhibitors; Imidazoles; Leptin; Male; Myocardial Contraction; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Obesity; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Leptin; Tyrphostins | 2008 |
Leptin and leptin receptor expression in asthma.
Topics: Adult; Androstadienes; Asthma; Bronchi; Cell Line; Cell Proliferation; Chromones; Enzyme Inhibitors; Female; Fluticasone; Humans; Imidazoles; Leptin; Male; Middle Aged; Morpholines; Pyridines; Receptors, Leptin; Recombinant Proteins; Respiratory Mucosa; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2009 |
C-reactive protein impairs hepatic insulin sensitivity and insulin signaling in rats: role of mitogen-activated protein kinases.
Topics: Adiponectin; Animals; Butadienes; C-Reactive Protein; Glucose Clamp Technique; Humans; Imidazoles; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Interleukin-6; Leptin; Liver; Male; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Necrosis Factor-alpha | 2011 |
Leptin attenuates lipopolysaccharide-induced apoptosis of thymocytes partially via down-regulation of cPLA2 and p38 MAPK activation.
Topics: Animals; Apoptosis; Caspase 3; Cells, Cultured; Cytoprotection; Down-Regulation; Imidazoles; Leptin; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; p38 Mitogen-Activated Protein Kinases; Phospholipases A2, Cytosolic; Pyridines; RNA, Messenger; Signal Transduction; T-Lymphocytes; Thymus Gland | 2013 |
Early intracellular signaling events induced by in vitro metreleptin administration in cardiac myocytes and uterine smooth muscle cells.
Topics: Anthracenes; Cell Line; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Imidazoles; Janus Kinase 2; JNK Mitogen-Activated Protein Kinases; Leptin; Muscle, Smooth; Myocytes, Cardiac; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; STAT3 Transcription Factor; Uterus | 2015 |
Angiotensin-(1-7) protects cardiomyocytes against high glucose-induced injuries through inhibiting reactive oxygen species-activated leptin-p38 mitogen-activated protein kinase/extracellular signal-regulated protein kinase 1/2 pathways, but not the leptin
Topics: Acetylcysteine; Angiotensin I; Animals; Anthracenes; Apoptosis; Cell Line; Glucose; Imidazoles; Leptin; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Myocytes, Cardiac; Peptide Fragments; Pyridines; Rats; Reactive Oxygen Species | 2017 |