sb 203580 and kn 93

Topics: Amiodarone; Animals; Anthrax; Antigens, Bacterial; Bacterial Toxins; Bepridil; Cell Line; Cell Survival; Chloroquine; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Macrophages, Peritoneal; Male; Mice; Molecular Structure; Rats; Rats, Inbred F344; Time Factors

Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

Topics: Animals; Benzylamines; Blotting, Western; Butadienes; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Circadian Rhythm; Cricetinae; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Flavonoids; Imidazoles; In Situ Hybridization; Light; Male; MAP Kinase Signaling System; Mesocricetus; Mitogen-Activated Protein Kinase Kinases; Motor Activity; Nerve Tissue Proteins; Nitriles; Nuclear Proteins; Period Circadian Proteins; Pyridines; RNA, Messenger; Sulfonamides; Suprachiasmatic Nucleus; Transcription Factors

Topics: Animals; Benzylamines; Bridged-Ring Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Enzyme Inhibitors; Flavonoids; I-kappa B Kinase; I-kappa B Proteins; Imidazoles; Indoles; Lipopolysaccharides; Macrophages; Macrophages, Peritoneal; Mitogen-Activated Protein Kinases; NF-kappa B; Norbornanes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Receptors, Purinergic P2; Sulfonamides; Thapsigargin; Thiocarbamates; Thiones; Time Factors; Transcription Factor RelA; Uridine Triphosphate

Topics: Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzylamines; Butadienes; Cattle; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Enzyme Inhibitors; Imidazoles; Isoquinolines; Losartan; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Phosphoserine; Protein Processing, Post-Translational; Proto-Oncogene Proteins pp60(c-src); Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Ribosomal Protein S6 Kinases; src-Family Kinases; Sulfonamides

Topics: Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cell Line, Tumor; Colonic Neoplasms; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Osmolar Concentration; Pyridines; RNA, Messenger; Sulfonamides

Topics: Animals; Base Sequence; Benzylamines; Binding Sites; Bucladesine; Carbazoles; Cell Nucleus; CHO Cells; Cricetinae; Cyclic AMP; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; GATA6 Transcription Factor; Humans; Imidazoles; Indole Alkaloids; Isoquinolines; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Molecular Sequence Data; Mutation; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plasmids; Prostaglandin D2; Proteasome Endopeptidase Complex; Protein Binding; Pyridines; src-Family Kinases; Sulfonamides; Transcription Factors

Topics: Active Transport, Cell Nucleus; Amino Acid Substitution; Animals; Arachidonate 5-Lipoxygenase; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Nucleus; Cricetinae; Dogs; Humans; Imidazoles; Leukotrienes; MAP Kinase Kinase 2; Mice; Mutation, Missense; NIH 3T3 Cells; Nuclear Export Signals; Opossums; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines; Rabbits; Rats; Serine; Sulfonamides

Topics: Animals; Benzylamines; Calcitonin Gene-Related Peptide; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Ganglia, Spinal; Imidazoles; Immunohistochemistry; Male; Morphine; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Posterior Horn Cells; Pyridines; Rats; Rats, Sprague-Dawley; Sulfonamides

Topics: Adolescent; Adult; Alkaline Phosphatase; Anthracenes; Benzylamines; Butadienes; Calcium Compounds; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Culture Techniques; Cell Differentiation; Dental Pulp; Extracellular Matrix Proteins; Humans; Imidazoles; Integrin-Binding Sialoprotein; MAP Kinase Signaling System; NF-kappa B; Nitriles; Odontoblasts; Osteocalcin; Phosphoproteins; Protein Kinase Inhibitors; Pulp Capping and Pulpectomy Agents; Pyridines; Pyrrolidines; Sialoglycoproteins; Signal Transduction; Silicates; Stem Cells; Sulfonamides; Thiocarbamates; Young Adult