Page last updated: 2024-09-05

sb 203580 and interleukin-8

sb 203580 has been researched along with interleukin-8 in 106 studies

Compound Research Comparison

Studies
(sb 203580)
Trials
(sb 203580)
Recent Studies (post-2010)
(sb 203580)
Studies
(interleukin-8)
Trials
(interleukin-8)
Recent Studies (post-2010) (interleukin-8)
3,48941,13723,5231,1679,990

Research

Studies (106)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (7.55)18.2507
2000's62 (58.49)29.6817
2010's35 (33.02)24.3611
2020's1 (0.94)2.80

Authors

AuthorsStudies
Dinarello, CA; Shapiro, L1
Bigg, HF; Cawston, TE; DeWitt, DL; Lee, JC; Ridley, SH; Saklatvala, J; Sarsfield, SJ; Taylor, DJ1
Fernandez, GA; Gilchrist, A; Huang, CK; Kreutzer, DL; Qi, J; Sha'afi, RI; Vazquez-Abad, D; Zu, YL1
Chen, LM; Davis, RJ; Galán, JE; Hobbie, S1
Gon, Y; Hashimoto, S; Horie, T; Matsumoto, K; Nakayama, T; Takeshita, I1
Gon, Y; Hashimoto, S; Hayashi, S; Horie, T; Koura, T; Kujime, K; Maruoka, S; Matsumoto, K; Takeshita, I1
Chang, JH; Eberhardt, W; Frank, S; Mühl, H; Nold, M; Pfeilschifter, J1
Keates, AC; Keates, S; Kelly, CP; Murray, PG; Peek, RM; Warny, M1
Gon, Y; Hashimoto, S; Horie, T; Jibiki, I; Kudoh, S; Matsumoto, K; Takeshita, I; Takizawa, H1
Kobayashi, M; Matsui, N; Okamoto, T; Suzuki, M; Tetsuka, T; Watanabe, N; Yoshida, S1
Asai, Y; Gon, Y; Hashimoto, S; Hayashi, S; Horie, T; Jibiki, I; Machino, T; Maruoka, S; Matsumoto, K; Takeshita, I1
Gerthoffer, WT; Hedges, JC; Singer, CA1
Fahy, O; Hammad, H; Pestel, J; Sénéchal, S; Tonnel, AB; Tsicopoulos, A; Wallaert, B1
Arai, N; Araya, J; Fujita, T; Hayashi, R; Kashii, T; Kobayashi, M; Maruyama, M; Matsui, S; Sassa, K; Sugiyama, E; Yamashita, N; Yoshida, Y1
Adams, JL; Dillon, SB; Griego, SD; Tal-Singer, R; Weston, CB1
Bosmann, M; Chang, JH; Hellmuth, M; Huwiler, A; Mühl, H; Ninic, R; Nold, M; Paulukat, J; Pfeilschifter, J1
Desaki, M; Kasama, T; Kawasaki, S; Kobayashi, K; Nakahara, K; Ohtoshi, T; Okazaki, H; Sagai, M; Takami, K; Takizawa, H; Tanaka, M; Yamamoto, K1
Funakoshi, M; Kasahara, T; Sonoda, Y; Tago, K; Tominaga, S1
Klein, JP; Neff, L; Schöller-Guinard, M; Sibilia, J; Wachsmann, D; Zeisel, M1
Kato, H; Kawakami, A; Nawa, C; Numano, F; Uchimura, I1
Barr, CE; Kreutzer, D; Sfakianakis, A1
Cao, BZ; Jing, Q; Lei, ZB; Li, XY; Pei, G; Qin, YW; Zhang, Z1
Frewin, MB; Gudewicz, PW; Xythalis, D1
Oudin, S; Pugin, J1
Bakheet, T; Frevel, MA; Hissong, JG; Khabar, KS; Silva, AM; Williams, BR1
Brockman-Schneider, RA; Busse, WW; French, DA; Gern, JE; Grindle, KA; Konno, S1
Nelson, C; Parhar, K; Ray, A; Salh, B; Steinbrecher, U1
Dai, J; Remick, DG; Wang, X; Zeng, X1
Butt, W; Chen, Q; Coxon, PY; McLeish, KR; Powell, DW; Rane, MJ; Singh, S; Uriarte, S1
Coppens, A; Hooghe-Peters, E; Kooijman, R1
Abrahamsen, MS; Maheswaran, SK; Malazdrewich, C; Thumbikat, P1
Chung, KS; Hoe, KL; Jang, YJ; Kim, DU; Maeng, PJ; Oh, GT; Park, SK; Ryoo, SW; Won, M; Yoo, HS1
Denis, MG; Galmiche, JP; Jarry, A; Laboisse, CL; Neunlist, M; Oreshkova, T; Toumi, F1
Li, N; Liboni, K; Neu, J1
D'Isanto, M; Galdiero, M; Peluso, L; Raieta, K; Rotondo, P; Tortora, A; Vitiello, M1
Kang, J; Khan, MA; Steiner, TS1
Augstein, A; Fichtner, F; Hempel, U; Kasper, M; Koslowski, R; Röhlecke, C1
Hammerschmidt, S; Hippenstiel, S; Hocke, AC; Hoffmann, E; Huber, S; Kracht, M; Moog, K; Opitz, B; Rosseau, S; Schmeck, B; Suttorp, N; van Laak, V; Zahlten, J; Zerrahn, J1
Fujita, T; Kurihara, H; Van Dyke, TE; Zawawi, KH1
Ip, WK; Lam, CW; Tian, YP; Wang, CB; Wong, CK1
Brunius, G; Domeij, H; Gustavsson, A; Yucel-Lindberg, T1
Feng, Y; Li, X; Wang, BY; Wang, F; Wu, Q1
Wu, XY; Yu, FS; Zhang, J1
Foster, GH; Rubin, BK; Shinkai, M1
Kim, JY; Ro, JY1
Jung, HY; Kim, JM; Kim, KH; Lee, CH; Lee, JY; Youn, J1
Rydkina, E; Sahni, SK; Silverman, DJ1
Abdollahi, A; Abdollahi, T; Litwack, G; Robertson, NM1
Colarusso, P; Heit, B; Kubes, P1
Ahn, MJ; Kim, JM; Kim, NI; Kim, YJ; Oh, YK; Youn, J1
Khatri, M; Sharma, JM1
Beales, IL; Ogunwobi, OO1
Medin, CL; Rothman, AL1
Abdel-Latif, MM; Eidhin, DN; Kelleher, D; Reynolds, JV; Terres, A; Windle, H1
Fukuda, Y; Goto, M; Terakawa, M; Tomimori, Y1
Fu, Y; He, S; Luo, J; Wang, L1
Chen, YH; Hsieh, HC; Hsueh, CH; Liu, YH; Tsai, PJ; Tsou, CC; Wu, JJ1
Fukuda, S; Hiraga, H; Ishiguro, Y; Munakata, A; Nakane, A; Nishihira, J; Ohkawara, T; Sakuraba, H; Yamagata, K; Yamaguchi, S1
Gonsalves, C; Johnson, C; Kalra, VK; Kim, KS; Rajagopal, V1
Azakami, H; Ebisu, S; Matsuo, T; Nakae, H; Shinohara, C; Takahashi, K; Yamada, M; Yumoto, H1
Ayada, K; Oguma, K; Okada, T; Shen, L; Yamamoto, Y; Yokota, K; Zhao, Y1
Dow, KE; Ji, P; Nan, X; Wang, W1
Han, JS; Kim, JM; Kim, YJ; Lee, JY; Oh, YK; Park, HR; Youn, J1
Guo, XL; Noel, G; Ogle, CK; Pritts, TA; Wang, Q; Wells-Byrum, D1
Bachelet, M; Bardin, S; Broquet, AH; Gasnereau, I; Jouniaux, AM; Lenoir, C; Masliah, J; Sapin, C; Seksik, P; Thomas, G; Trugnan, G1
Chang, YL; Guh, JH; Huang, DY; Pan, SL; Sun, HL; Tao, KY; Teng, CM1
Binion, DG; Floer, M; Manley, S; Nelson, VM; Rafiee, P; Shaker, R; Wellner, M1
Bhakdi, S; Dersch, K; Dragneva, Y; Fenske, D; Han, SR; Husmann, M; Lux, C; Suriyaphol, P; Zipse, L1
Gong, W; Holden, NS; King, EM; Newton, R; Rider, CF1
Adner, M; Benson, M; Björnsson, S; Cardell, LO; Fransson, M; Månsson, A; Uddman, R1
He, JG; Li, JJ; Nan, JL1
Raddatzc, D; Ramadori, G; Sunil, Y1
Ammit, AJ; Ge, Q; Laufer, S; Manetsch, M; Munoz, L; Peifer, C; Ramsay, EE1
Itabe, H; Kato, R; Obama, T; Sakiyama, Y; Suzuki, K; Usui, M; Yamamoto, M1
Hosokawa, I; Hosokawa, Y; Matsuo, T; Nakae, H; Ozaki, K; Yumoto, H1
Carraro, F; Filippi, I; Giavazzi, R; Miglietta, D; Moschetta, M; Naldini, A1
Fukami, T; Mizuno, K; Nakajima, M; Toyoda, Y; Yokoi, T1
Bröll, J; Kloesch, B; Liszt, M; Steiner, G1
Chao, KC; Chen, HL; Chen, HW; Chen, LL; Chiou, SH; Huang, TF; Hung, SC; Hung, YT; Li, HY; Tsai, KS; Yew, TL1
Dittrich-Breiholz, O; Feng, H; Gerhard, R; Just, I; Kracht, M; Meyer, G; Queisser, S; Tatge, H1
Dauletbaev, N; Di Marco, S; Eklove, D; Gallouzi, IE; Iskandar, M; Lands, LC; Mawji, N1
Asano, Y; Hau, CS; Kadono, T; Kanda, N; Sato, S; Shibata, S; Sugaya, M; Tada, Y; Tamaki, K; Uratsuji, H; Watanabe, S1
He, SZ; Jian, CX; Li, CJ; Liu, XC; Liu, XF1
Dong, S; Wang, J1
Huang, M; Liao, Y; Liu, DX; Tam, JP; Wang, X1
Aso, H; Hasegawa, Y; Imaizumi, K; Ito, S; Kondo, M; Mori, A; Morioka, M; Suganuma, N1
Abd-Elmeguid, A; Kline, LW; Moqbel, R; Vliagoftis, H; Yu, DC1
Ammit, AJ; Che, W; Chen, Y; Manetsch, M; Seidel, P1
Chen, XM; Drescher, KM; Gong, AY; Hu, G; Li, X; Zhou, R1
Furukawa, Y; Ishii, T; Karakida, S; Kawano, Y; Kira, N; Narahara, H1
Barnes, PJ; Chung, KF; Hakim, A; Ito, K; Kobayashi, Y; Meah, S; Mercado, N; Usmani, OS1
Eger, A; Hofmann, E; Hundsberger, H; Jacobi, N; Jokela, J; Kapuscik, A; Katzlinger, M; Kopecky, J; Koppensteiner, A; Lucas, R; Onder, K; Pflüger, M; Schütt, W; Wiesner, C1
Harris, T; Mackay, GA; Stewart, AG; Xia, YC1
Imamura, E; Magata, F; Miyamoto, A; Murayama, C; Shimizu, T1
Chang, GQ; Gao, W; Jin, WN; Li, QH; Lin, YN; Ma, L; Pang, TX; Ru, RX; Zhang, HJ; Zhang, HR; Zhang, YJ1
Liu, Y; Shi, HL; Wu, XJ; Xie, JQ1
Li, X; Zhang, Y1
Blasco, F; Fu, Y; Hervé, M; Seah, PG; Shi, PY; Yip, A1
Al-Jahdali, H; Al-Kufaidy, R; Al-Muhsen, S; Alnassar, SA; BaHammam, AS; Halwani, R; Hamid, Q; Pureza, MA; Vazquez-Tello, A1
Aziz, M; Chaung, WW; Corbo, LM; Matsuo, S; Wang, P; Yang, WL1
Gu, A; Mo, Y; Tollerud, DJ; Wan, R; Zhang, Q; Zhang, Y1
Jia, CZ; Luo, JM; Wang, L; Zhu, ZY1
Du, K; Li, Q; Liu, XZ; Zhou, M1
Choi, C; Cui, C; Hou, J; Kim, S; Sung, C1
Guang, Y; Hu, SH; Wang, WX1
Cui, T; Guo, Y; He, J; Hu, W; Li, C; Liu, R; Wang, X; Yin, C1

Other Studies

106 other study(ies) available for sb 203580 and interleukin-8

ArticleYear
Osmotic regulation of cytokine synthesis in vitro.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Dec-19, Volume: 92, Issue:26

    Topics: Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cells, Cultured; DNA Primers; Enzyme Inhibitors; Gene Expression; Humans; Imidazoles; Interleukin-1; Interleukin-8; Kinetics; Leukocytes, Mononuclear; Lymphocytes; Macrophages; Molecular Sequence Data; Osmolar Concentration; Polymerase Chain Reaction; Potassium Iodide; Pyridines; RNA, Messenger; Sodium Chloride

1995
Actions of IL-1 are selectively controlled by p38 mitogen-activated protein kinase: regulation of prostaglandin H synthase-2, metalloproteinases, and IL-6 at different levels.
    Journal of immunology (Baltimore, Md. : 1950), 1997, Apr-01, Volume: 158, Issue:7

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cartilage; Collagenases; Endothelium, Vascular; Fibroblasts; Humans; Imidazoles; Interleukin-1; Interleukin-6; Interleukin-8; Matrix Metalloproteinase 3; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Proteoglycans; Pyridines

1997
p38 mitogen-activated protein kinase activation is required for human neutrophil function triggered by TNF-alpha or FMLP stimulation.
    Journal of immunology (Baltimore, Md. : 1950), 1998, Feb-15, Volume: 160, Issue:4

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Chemotaxis, Leukocyte; Down-Regulation; Enzyme Activation; Humans; Imidazoles; Interleukin-8; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; p38 Mitogen-Activated Protein Kinases; Pyridines; Superoxides; Tumor Necrosis Factor-alpha

1998
Involvement of mitogen-activated protein kinase pathways in the nuclear responses and cytokine production induced by Salmonella typhimurium in cultured intestinal epithelial cells.
    Journal of immunology (Baltimore, Md. : 1950), 1997, Dec-01, Volume: 159, Issue:11

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Cells, Cultured; Enzyme Inhibitors; Epithelial Cells; Humans; Imidazoles; Interleukin-8; Intestines; Mutation; NF-kappa B; Pyridines; Salmonella typhimurium; Signal Transduction; Transcription Factor AP-1; Transfection

1997
Hyperosmolarity-induced interleukin-8 expression in human bronchial epithelial cells through p38 mitogen-activated protein kinase.
    American journal of respiratory and critical care medicine, 1999, Volume: 159, Issue:2

    Topics: Blotting, Northern; Blotting, Western; Bronchi; Bronchial Hyperreactivity; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Gene Expression; Humans; Imidazoles; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Mannitol; Mitogen-Activated Protein Kinases; Osmolar Concentration; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; RNA, Messenger; Saline Solution, Hypertonic; Signal Transduction; Tyrosine

1999
p38 Mitogen-activated protein kinase regulates IL-8 expression in human pulmonary vascular endothelial cells.
    The European respiratory journal, 1999, Volume: 13, Issue:6

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Interleukin-1; Interleukin-8; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pulmonary Artery; Pyridines; Tumor Necrosis Factor-alpha

1999
Expression and release of chemokines associated with apoptotic cell death in human promonocytic U937 cells and peripheral blood mononuclear cells.
    European journal of immunology, 1999, Volume: 29, Issue:10

    Topics: Apoptosis; Chemokines; Cladribine; Enzyme Inhibitors; Etoposide; Humans; Imidazoles; Interleukin-8; Leukocytes, Mononuclear; Pyridines; Serine Proteinase Inhibitors; Tosylphenylalanyl Chloromethyl Ketone; Triazenes; Tumor Necrosis Factor-alpha; U937 Cells

1999
Differential activation of mitogen-activated protein kinases in AGS gastric epithelial cells by cag+ and cag- Helicobacter pylori.
    Journal of immunology (Baltimore, Md. : 1950), 1999, Nov-15, Volume: 163, Issue:10

    Topics: Antigens, Bacterial; Bacterial Proteins; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Gastric Mucosa; Helicobacter pylori; Humans; I-kappa B Proteins; Imidazoles; Interleukin-8; Mitogen-Activated Protein Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; Pyridines; Tumor Cells, Cultured; Up-Regulation

1999
Diesel exhaust particles activate p38 MAP kinase to produce interleukin 8 and RANTES by human bronchial epithelial cells and N-acetylcysteine attenuates p38 MAP kinase activation.
    American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:1

    Topics: Acetylcysteine; Blotting, Western; Bronchi; Cells, Cultured; Chemokine CCL5; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Humans; Imidazoles; Interleukin-8; Mitogen-Activated Protein Kinases; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; Threonine; Tyrosine; Vehicle Emissions

2000
The role of p38 mitogen-activated protein kinase in IL-6 and IL-8 production from the TNF-alpha- or IL-1beta-stimulated rheumatoid synovial fibroblasts.
    FEBS letters, 2000, Jan-07, Volume: 465, Issue:1

    Topics: Arthritis, Rheumatoid; Cell Nucleus; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Interleukin-1; Interleukin-6; Interleukin-8; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyridines; RNA, Messenger; Synovial Membrane; Tumor Necrosis Factor-alpha

2000
Selective inhibitor of p38 mitogen-activated protein kinase inhibits lipopolysaccharide-induced interleukin-8 expression in human pulmonary vascular endothelial cells.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:2

    Topics: Blotting, Northern; Blotting, Western; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Interleukin-8; Lipopolysaccharides; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pulmonary Artery; Pyridines; RNA, Messenger

2000
Mitogen-activated protein kinases regulate cytokine gene expression in human airway myocytes.
    American journal of respiratory cell and molecular biology, 2000, Volume: 23, Issue:1

    Topics: Anti-Inflammatory Agents; Bronchi; Cell Line; Cytokines; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Inflammation; Interleukin-1; Interleukin-6; Interleukin-8; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Muscle, Smooth; p38 Mitogen-Activated Protein Kinases; Pyridines; RNA, Messenger

2000
Synergistic effect of diesel organic extracts and allergen Der p 1 on the release of chemokines by peripheral blood mononuclear cells from allergic subjects: involvement of the map kinase pathway.
    American journal of respiratory cell and molecular biology, 2000, Volume: 23, Issue:2

    Topics: Antigens, Dermatophagoides; Cell Survival; Cells, Cultured; Chemokine CCL2; Chemokine CCL5; Chemokines; Chemotaxis; Child, Preschool; Culture Media, Conditioned; Cytokines; Drug Synergism; Enzyme Inhibitors; Flavonoids; Glutathione; Glycoproteins; Humans; Hypersensitivity; Imidazoles; Interleukin-8; Leukocytes, Mononuclear; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Pyridines; Reactive Oxygen Species; RNA, Messenger; Tumor Necrosis Factor-alpha; Vehicle Emissions

2000
Bradykinin stimulates IL-6 and IL-8 production by human lung fibroblasts through ERK- and p38 MAPK-dependent mechanisms.
    The European respiratory journal, 2000, Volume: 16, Issue:3

    Topics: Blotting, Northern; Blotting, Western; Bradykinin; Cells, Cultured; Enzyme Inhibitors; Fibroblasts; Flavonoids; Humans; Imidazoles; Interleukin-6; Interleukin-8; Lung; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; RNA, Messenger; Signal Transduction

2000
Role of p38 mitogen-activated protein kinase in rhinovirus-induced cytokine production by bronchial epithelial cells.
    Journal of immunology (Baltimore, Md. : 1950), 2000, Nov-01, Volume: 165, Issue:9

    Topics: Bronchi; Cell Line; Cytokines; Enzyme Inhibitors; Epithelial Cells; HeLa Cells; Humans; Imidazoles; Interleukin-1; Interleukin-8; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Picornaviridae Infections; Pyridines; Rhinovirus; RNA, Messenger; Tyrosine; Ultraviolet Rays; Virus Activation

2000
Nitric oxide augments release of chemokines from monocytic U937 cells: modulation by anti-inflammatory pathways.
    Free radical biology & medicine, 2000, Nov-15, Volume: 29, Issue:10

    Topics: Chemokine CCL4; Chemokines; Cyclic AMP; Dexamethasone; Enzyme Inhibitors; Genistein; Humans; Imidazoles; Inflammation; Interleukin-8; Macrophage Inflammatory Proteins; Mitogen-Activated Protein Kinases; Monocytes; Nitric Oxide; Nitric Oxide Donors; p38 Mitogen-Activated Protein Kinases; Protein-Tyrosine Kinases; Pyridines; Signal Transduction; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Triazenes; U937 Cells

2000
Benzene-extracted components are important for the major activity of diesel exhaust particles: effect on interleukin-8 gene expression in human bronchial epithelial cells.
    American journal of respiratory cell and molecular biology, 2001, Volume: 24, Issue:4

    Topics: Acetylcysteine; Antioxidants; Benzene; Bronchi; Cell Line; Chemokine CCL5; Enzyme Inhibitors; Epithelial Cells; Free Radical Scavengers; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; In Vitro Techniques; Interleukin-8; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrrolidines; RNA, Messenger; T-Lymphocytes; Thiocarbamates; Vehicle Emissions

2001
Differential involvement of p38 mitogen-activated protein kinase and phosphatidyl inositol 3-kinase in the IL-1-mediated NF-kappa B and AP-1 activation.
    International immunopharmacology, 2001, Volume: 1, Issue:3

    Topics: Chromones; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Interleukin-1; Interleukin-8; Mitogen-Activated Protein Kinases; Morpholines; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proteins; Pyridines; Signal Transduction; TNF Receptor-Associated Factor 6; Transcription Factor AP-1; Tumor Cells, Cultured

2001
NF-kappaB and the MAP kinases/AP-1 pathways are both involved in interleukin-6 and interleukin-8 expression in fibroblast-like synoviocytes stimulated by protein I/II, a modulin from oral streptococci.
    Cellular microbiology, 2001, Volume: 3, Issue:10

    Topics: Anti-Bacterial Agents; Apigenin; Arthritis, Rheumatoid; Bacterial Proteins; Cells, Cultured; Curcumin; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Interleukin-6; Interleukin-8; MAP Kinase Signaling System; Membrane Glycoproteins; NF-kappa B; Pyridines; Signal Transduction; Streptococcus; Sulfasalazine; Synovial Membrane

2001
Fluid shear stress suppresses interleukin 8 production by vascular endothelial cells.
    Biorheology, 2001, Volume: 38, Issue:4

    Topics: Arteriosclerosis; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Glucose; Humans; Imidazoles; Interleukin-8; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Polymerase Chain Reaction; Pyridines; Regional Blood Flow; Rheology; RNA, Messenger; Stimulation, Chemical; Stress, Mechanical; Time Factors; Umbilical Veins

2001
Mechanisms of Actinobacillus actinomycetemcomitans-induced expression of interleukin-8 in gingival epithelial cells.
    Journal of periodontology, 2001, Volume: 72, Issue:10

    Topics: Aggregatibacter actinomycetemcomitans; Anti-Bacterial Agents; Cell Line; Coloring Agents; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Escherichia coli; Gene Expression Regulation, Bacterial; Gingiva; Humans; Imidazoles; Interleukin-8; Leukocytes, Mononuclear; Lipopolysaccharides; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Polymyxin B; Pyridines; Signal Transduction; Statistics as Topic; Time Factors; Up-Regulation

2001
OxLDL upregulates CXCR2 expression in monocytes via scavenger receptors and activation of p38 mitogen-activated protein kinase.
    Cardiovascular research, 2002, Feb-01, Volume: 53, Issue:2

    Topics: Cell Adhesion; Chemotaxis, Leukocyte; Coculture Techniques; Dextran Sulfate; Endothelium, Vascular; Enzyme Activation; Flow Cytometry; Humans; Imidazoles; Interleukin-8; Lipoproteins, LDL; Membrane Proteins; Mitogen-Activated Protein Kinases; Monocytes; p38 Mitogen-Activated Protein Kinases; Poly I; Pyridines; Receptors, Immunologic; Receptors, Interleukin-8B; Receptors, Lipoprotein; Receptors, Scavenger; RNA, Messenger; Scavenger Receptors, Class B; Thiazoles; U937 Cells

2002
Inhibition of IL-8-mediated MAPK activation in human neutrophils by beta1 integrin ligands.
    Inflammation, 2002, Volume: 26, Issue:2

    Topics: Antibodies, Monoclonal; Chemotaxis, Leukocyte; Enzyme Activation; Enzyme Inhibitors; Fibronectins; Flavonoids; Humans; Imidazoles; Integrin alpha5beta1; Integrin alpha6beta1; Integrin beta1; Interleukin-8; Laminin; Ligands; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neutrophils; Oligopeptides; Peptide Fragments; Phosphorylation; Protein Processing, Post-Translational; Pyridines; Recombinant Proteins

2002
Role of MAP kinase activation in interleukin-8 production by human BEAS-2B bronchial epithelial cells submitted to cyclic stretch.
    American journal of respiratory cell and molecular biology, 2002, Volume: 27, Issue:1

    Topics: Bronchi; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Interleukin-8; Mitogen-Activated Protein Kinases; Models, Biological; Phosphorylation; Pyridines; Respiratory Mucosa; RNA, Messenger; Stress, Mechanical

2002
p38 Mitogen-activated protein kinase-dependent and -independent signaling of mRNA stability of AU-rich element-containing transcripts.
    Molecular and cellular biology, 2003, Volume: 23, Issue:2

    Topics: Blotting, Northern; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cells, Cultured; Cyclooxygenase 2; DNA, Complementary; Down-Regulation; Enzyme Inhibitors; Genome, Human; Humans; Imidazoles; Interleukin-1; Interleukin-8; Isoenzymes; Lipopolysaccharides; Macrophages; MAP Kinase Kinase 6; Membrane Proteins; Mitogen-Activated Protein Kinases; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Pyridines; RNA, Messenger; Signal Transduction; Time Factors; Up-Regulation

2003
Double-stranded RNA induces the synthesis of specific chemokines by bronchial epithelial cells.
    American journal of respiratory cell and molecular biology, 2003, Volume: 28, Issue:6

    Topics: Bronchi; Cell Line, Transformed; Cells, Cultured; Chemokine CCL11; Chemokine CCL5; Chemokines; Chemokines, CC; eIF-2 Kinase; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Humans; Imidazoles; Interleukin-8; Kinetics; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Polynucleotides; Pyridines; Rhinovirus; RNA, Double-Stranded; RNA, Viral; Signal Transduction; Transfection

2003
The p38 mitogen-activated protein kinase regulates interleukin-1beta-induced IL-8 expression via an effect on the IL-8 promoter in intestinal epithelial cells.
    Immunology, 2003, Volume: 108, Issue:4

    Topics: Cell Line; Chemokine CCL2; DNA-Binding Proteins; Enzyme Inhibitors; Epithelial Cells; Humans; I-kappa B Proteins; Imidazoles; Interleukin-1; Interleukin-8; Intestinal Mucosa; Mitogen-Activated Protein Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Transcriptional Activation

2003
Homocysteine mediated expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human monocytes.
    Circulation research, 2003, Aug-22, Volume: 93, Issue:4

    Topics: Antioxidants; Cells, Cultured; Chemokine CCL2; Chromans; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Genistein; Homocysteine; Humans; Imidazoles; Indoles; Interleukin-8; Monocytes; Naphthalenes; Onium Compounds; Pyridines; Pyrrolidines; Reactive Oxygen Species; RNA, Messenger; Sulfonamides; Thiazoles; Thiazolidinediones; Thiocarbamates; Time Factors; Troglitazone; Tyrphostins

2003
MAPK-activated protein kinase-2 participates in p38 MAPK-dependent and ERK-dependent functions in human neutrophils.
    Cellular signalling, 2003, Volume: 15, Issue:11

    Topics: Chemotaxis, Leukocyte; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Flavonoids; Humans; Imidazoles; Interleukin-8; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; Respiratory Burst; Signal Transduction; Superoxides

2003
IGF-I stimulates IL-8 production in the promyelocytic cell line HL-60 through activation of extracellular signal-regulated protein kinase.
    Cellular signalling, 2003, Volume: 15, Issue:12

    Topics: Androstadienes; Anthracenes; Apoptosis; Butadienes; Cell Survival; Chromones; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Hydrogen Peroxide; Imidazoles; Insulin-Like Growth Factor I; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Kinetics; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Oxazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptor, IGF Type 1; RNA, Messenger; Wortmannin

2003
Pharmacological inhibition of Mannheimia haemolytica lipopolysaccharide and leukotoxin-induced cytokine expression in bovine alveolar macrophages.
    Microbial pathogenesis, 2004, Volume: 36, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Cattle; Cells, Cultured; Cytokines; Dexamethasone; Exotoxins; Gene Expression Regulation; Imidazoles; Interleukin-1; Interleukin-8; Lipopolysaccharides; Macrophages, Alveolar; Mannheimia haemolytica; Pentoxifylline; Pyridines; RNA, Messenger; Rolipram; Tetrahydropapaveroline; Thalidomide; Tumor Necrosis Factor-alpha

2004
Native LDL induces interleukin-8 expression via H2O2, p38 Kinase, and activator protein-1 in human aortic smooth muscle cells.
    Cardiovascular research, 2004, Apr-01, Volume: 62, Issue:1

    Topics: Aorta; Caffeic Acids; Cells, Cultured; Coronary Vessels; Dactinomycin; Dose-Response Relationship, Drug; Flavonoids; Humans; Hydrogen Peroxide; Imidazoles; Interleukin-8; Lipoproteins, LDL; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Pyridines; Sesquiterpenes; Time Factors; Transcription Factor AP-1; Tumor Necrosis Factor-alpha

2004
Vasoactive intestinal peptide induces IL-8 production in human colonic epithelial cells via MAP kinase-dependent and PKA-independent pathways.
    Biochemical and biophysical research communications, 2004, Apr-23, Volume: 317, Issue:1

    Topics: Cell Polarity; Colon; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Flavonoids; HT29 Cells; Humans; Imidazoles; Interleukin-8; Intestinal Mucosa; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; RNA, Messenger; Vasoactive Intestinal Peptide

2004
Mechanism of glutamine-mediated amelioration of lipopolysaccharide-induced IL-8 production in Caco-2 cells.
    Cytokine, 2004, Apr-21, Volume: 26, Issue:2

    Topics: Caco-2 Cells; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Electrophoretic Mobility Shift Assay; Glutamine; Humans; Imidazoles; Interleukin-8; Lipopolysaccharides; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Protein Array Analysis; Protein-Tyrosine Kinases; Pyridines; STAT4 Transcription Factor; Trans-Activators

2004
Interleukin-8 production by THP-1 cells stimulated by Salmonella enterica serovar Typhimurium porins is mediated by AP-1, NF-kappaB and MAPK pathways.
    Cytokine, 2004, Jul-07, Volume: 27, Issue:1

    Topics: Cell Line; Flavonoids; Humans; Imidazoles; Interleukin-8; Lipopolysaccharides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; NF-kappa B; Porins; Protein Binding; Pyridines; Salmonella typhimurium; Signal Transduction; Transcription Factor AP-1; Tyrphostins; Up-Regulation

2004
Enteroaggregative Escherichia coli flagellin-induced interleukin-8 secretion requires Toll-like receptor 5-dependent p38 MAP kinase activation.
    Immunology, 2004, Volume: 112, Issue:4

    Topics: Caco-2 Cells; Cell Line; Enzyme Inhibitors; Escherichia coli; Flagellin; Humans; Imidazoles; Interleukin-8; Intestinal Mucosa; Membrane Glycoproteins; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Pyridines; Receptors, Cell Surface; RNA, Messenger; Signal Transduction; Toll-Like Receptor 5; Toll-Like Receptors; Transfection

2004
Bleomycin induces IL-8 and ICAM-1 expression in microvascular pulmonary endothelial cells.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2004, Volume: 55, Issue:6

    Topics: Antibiotics, Antineoplastic; Bleomycin; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Interleukin-8; Lung; Microcirculation; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation

2004
Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor.
    The Journal of biological chemistry, 2004, Dec-17, Volume: 279, Issue:51

    Topics: Animals; Blotting, Western; Bronchi; Cell Nucleus; Cells, Cultured; Chemokines; Chromatin Immunoprecipitation; Cytokines; Dimerization; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Gene Expression Regulation, Enzymologic; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; Inflammation; Interleukin-8; Lung; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pneumonia; Promoter Regions, Genetic; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA Polymerase II; RNA, Complementary; Serine; Signal Transduction; Streptococcus pneumoniae; Time Factors; Transcription, Genetic; Transfection

2004
CD38 cleavage in fMLP- and IL-8-induced chemotaxis is dependent on p38 MAP kinase but independent of p44/42 MAP kinase.
    Cellular signalling, 2005, Volume: 17, Issue:2

    Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Chemotaxis; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression; Humans; Imidazoles; Interleukin-8; Membrane Glycoproteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphorylation; Pyridines; Receptors, Formyl Peptide; Receptors, Lipoxin; Tosyl Compounds

2005
Role of p38 MAPK and NF-kB for chemokine release in coculture of human eosinophils and bronchial epithelial cells.
    Clinical and experimental immunology, 2005, Volume: 139, Issue:1

    Topics: Bronchi; Cells, Cultured; Chemokine CCL2; Chemokine CCL5; Chemokine CXCL10; Chemokine CXCL9; Chemokines; Chemokines, CXC; Coculture Techniques; Enzyme Inhibitors; Eosinophils; Epithelial Cells; Fixatives; Formaldehyde; Gene Expression Regulation; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Interleukin-8; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Polymers; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Sulfones

2005
Bradykinin upregulates IL-8 production in human gingival fibroblasts stimulated by interleukin-1beta and tumor necrosis factor alpha.
    Regulatory peptides, 2005, Mar-30, Volume: 126, Issue:3

    Topics: Adolescent; Bradykinin; Bradykinin B2 Receptor Antagonists; Calcimycin; Cells, Cultured; Child; Fibroblasts; Gingiva; Humans; Imidazoles; Indoles; Interleukin-1; Interleukin-8; Ionophores; Kallidin; Maleimides; MAP Kinase Kinase 2; Protein Kinase C; Pyridines; Receptor, Bradykinin B2; Tumor Necrosis Factor-alpha; Up-Regulation

2005
[Involvement of MAPKs and NF-kappaB pathways in Pseudomonas pyocyanin-induced interleukin-8 expression by human airway epithelial cells].
    Wei sheng wu xue bao = Acta microbiologica Sinica, 2005, Volume: 45, Issue:1

    Topics: Butadienes; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Humans; Imidazoles; Interleukin-8; Mitogen-Activated Protein Kinases; NF-kappa B; Nitriles; Phosphorylation; Pyocyanine; Pyridines; Signal Transduction

2005
Inflammatory responses of corneal epithelial cells to Pseudomonas aeruginosa infection.
    Current eye research, 2005, Volume: 30, Issue:7

    Topics: Anthracenes; Blotting, Western; Cell Culture Techniques; Cytokines; Diterpenes; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Humans; I-kappa B Proteins; Imidazoles; Interleukin-6; Interleukin-8; JNK Mitogen-Activated Protein Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pseudomonas aeruginosa; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tumor Necrosis Factor-alpha

2005
Macrolide antibiotics modulate ERK phosphorylation and IL-8 and GM-CSF production by human bronchial epithelial cells.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 290, Issue:1

    Topics: Anti-Bacterial Agents; Azithromycin; Bronchi; Cells, Cultured; Clarithromycin; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; Interleukin-8; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reference Values; Threonine; Time Factors; Tyrosine

2006
Signal pathway of cytokines produced by reactive oxygen species generated from phorbol myristate acetate-stimulated HMC-1 cells.
    Scandinavian journal of immunology, 2005, Volume: 62, Issue:1

    Topics: Antioxidants; Free Radical Scavengers; Humans; Imidazoles; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Mast Cells; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thiourea; Transcription Factors; Tumor Necrosis Factor-alpha

2005
Mitogen-activated protein kinase and activator protein-1 dependent signals are essential for Bacteroides fragilis enterotoxin-induced enteritis.
    European journal of immunology, 2005, Volume: 35, Issue:9

    Topics: Animals; Bacterial Toxins; Bacteroides fragilis; Bacteroides Infections; Butadienes; Chemokine CCL2; Colon; Down-Regulation; Enteritis; HL-60 Cells; Humans; Imidazoles; Interleukin-8; Intestinal Mucosa; MAP Kinase Signaling System; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Nitriles; Protein Kinase Inhibitors; Pyridines; Specific Pathogen-Free Organisms; Transcription Factor AP-1

2005
Activation of p38 stress-activated protein kinase during Rickettsia rickettsii infection of human endothelial cells: role in the induction of chemokine response.
    Cellular microbiology, 2005, Volume: 7, Issue:10

    Topics: Cells, Cultured; Chemokine CCL2; Endothelium, Vascular; Enzyme Inhibitors; Humans; Imidazoles; Interleukin-8; MAP Kinase Kinase 4; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rickettsia rickettsii

2005
Inhibition of TRAIL-induced apoptosis by IL-8 is mediated by the p38-MAPK pathway in OVCAR3 cells.
    Apoptosis : an international journal on programmed cell death, 2005, Volume: 10, Issue:6

    Topics: Activating Transcription Factor 2; Apoptosis; Blotting, Western; Cell Line, Tumor; Enzyme Activation; Humans; Imidazoles; Interleukin-8; Isoenzymes; MAP Kinase Kinase 3; MAP Kinase Kinase 6; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; RNA, Small Interfering; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Transfection

2005
Fundamentally different roles for LFA-1, Mac-1 and alpha4-integrin in neutrophil chemotaxis.
    Journal of cell science, 2005, Nov-15, Volume: 118, Issue:Pt 22

    Topics: Chemotaxis, Leukocyte; Fibronectins; Humans; Imidazoles; Integrin alpha4; Intercellular Adhesion Molecule-1; Interleukin-8; Ligands; Lymphocyte Function-Associated Antigen-1; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pyridines; Signal Transduction; Vascular Cell Adhesion Molecule-1

2005
CpG oligodeoxynucleotides induce IL-8 expression in CD34+ cells via mitogen-activated protein kinase-dependent and NF-kappaB-independent pathways.
    International immunology, 2005, Volume: 17, Issue:12

    Topics: Antigens, CD34; Butadienes; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fetal Blood; GC Rich Sequence; Gene Expression Regulation; Hematopoietic Stem Cells; Humans; Imidazoles; Interleukin-8; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; NF-kappa B; Nitriles; Oligodeoxyribonucleotides; Pyridines; Toll-Like Receptor 9

2005
Infectious bursal disease virus infection induces macrophage activation via p38 MAPK and NF-kappaB pathways.
    Virus research, 2006, Volume: 118, Issue:1-2

    Topics: Animals; Cells, Cultured; Chickens; Cyclooxygenase 2; Enzyme Inhibitors; Gene Expression Regulation; Imidazoles; Immunohistochemistry; Infectious bursal disease virus; Interleukin-8; Macrophage Activation; Macrophages; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfones

2006
Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells.
    Regulatory peptides, 2006, May-15, Volume: 134, Issue:2-3

    Topics: Adiponectin; Cell Proliferation; Chemokine CCL2; Cytokines; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Granulocyte-Macrophage Colony-Stimulating Factor; HT29 Cells; Humans; Imidazoles; Indoles; Interleukin-1; Interleukin-8; Intestinal Mucosa; Isoquinolines; Maleimides; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Sulfonamides; Sulfones

2006
Cell type-specific mechanisms of interleukin-8 induction by dengue virus and differential response to drug treatment.
    The Journal of infectious diseases, 2006, Apr-15, Volume: 193, Issue:8

    Topics: Cell Line; Cell Line, Tumor; Dengue; Dengue Virus; Dexamethasone; DNA, Recombinant; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gene Expression; Genes, Reporter; Glucocorticoids; Humans; Imidazoles; Interleukin-8; Luciferases; NF-kappa B; Phosphodiesterase Inhibitors; Pyridines; Rolipram; Transcription Factor AP-1

2006
Helicobacter pylori extract induces nuclear factor-kappa B, activator protein-1, and cyclooxygenase-2 in esophageal epithelial cells.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:4

    Topics: Antioxidants; Ascorbic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Cell Extracts; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Enzyme Inhibitors; Epithelial Cells; Esophagus; Flavonoids; Helicobacter pylori; Humans; Imidazoles; Interleukin-8; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Pyridines; Signal Transduction; Transcription Factor AP-1

2006
Mast cell chymase induces expression of chemokines for neutrophils in eosinophilic EoL-1 cells and mouse peritonitis eosinophils.
    European journal of pharmacology, 2006, May-24, Volume: 538, Issue:1-3

    Topics: Animals; Butadienes; Cell Line, Tumor; Chemokine CXCL2; Chemokines; Chymases; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Eosinophils; Gene Expression; Humans; Imidazoles; Interleukin-8; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Neutrophils; Nitriles; Peritonitis; Pertussis Toxin; Pyridines; Quinazolines; RNA, Messenger; Serine Endopeptidases

2006
Induction of interleukin-8 secretion and activation of ERK1/2, p38 MAPK signaling pathways by thrombin in dermal fibroblasts.
    The international journal of biochemistry & cell biology, 2006, Volume: 38, Issue:9

    Topics: Adolescent; Adult; Butadienes; Chromones; Fibroblasts; Flavonoids; Humans; Imidazoles; Interleukin-8; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptors, Proteinase-Activated; Signal Transduction; Skin; STAT3 Transcription Factor; Thrombin; Tyrphostins

2006
Streptococcus pyogenes induces epithelial inflammatory responses through NF-kappaB/MAPK signaling pathways.
    Microbes and infection, 2006, Volume: 8, Issue:6

    Topics: Apigenin; Autoantibodies; Cell Movement; Chemotaxis; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Humans; Imidazoles; Interleukin-6; Interleukin-8; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Streptococcal Infections; Streptococcus pyogenes; Transcription Factor AP-1; U937 Cells

2006
Macrophage migration inhibitory factor has a proinflammatory activity via the p38 pathway in glucocorticoid-resistant ulcerative colitis.
    Clinical immunology (Orlando, Fla.), 2006, Volume: 120, Issue:3

    Topics: Adolescent; Adult; Aged; Biopsy; Child; Colitis, Ulcerative; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Female; Glucocorticoids; Humans; Imidazoles; Immunohistochemistry; Interleukin-8; Intestinal Mucosa; Macrophage Migration-Inhibitory Factors; Male; Middle Aged; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines

2006
A novel role of hypoxia-inducible factor in cobalt chloride- and hypoxia-mediated expression of IL-8 chemokine in human endothelial cells.
    Journal of immunology (Baltimore, Md. : 1950), 2006, Nov-15, Volume: 177, Issue:10

    Topics: Base Sequence; Cell Line, Transformed; Cells, Cultured; Chemokine CCL2; Chemotaxis, Leukocyte; Chromones; Cobalt; Endothelial Cells; Endothelium, Vascular; Flavonoids; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Imidazoles; Interleukin-8; Molecular Sequence Data; Morpholines; Protein Kinase Inhibitors; Pulmonary Artery; Pyridines; RNA, Messenger

2006
Soluble products from Eikenella corrodens induce cell proliferation and expression of interleukin-8 and adhesion molecules in endothelial cells via mitogen-activated protein kinase pathways.
    Oral microbiology and immunology, 2007, Volume: 22, Issue:1

    Topics: Cell Adhesion Molecules; Cell Line; Cell Proliferation; Cells, Cultured; Culture Media, Conditioned; E-Selectin; Eikenella corrodens; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Interleukin-8; KB Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Periodontitis; Phosphorylation; Pyridines; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A

2007
Helicobacter pylori heat-shock protein 60 induces interleukin-8 via a Toll-like receptor (TLR)2 and mitogen-activated protein (MAP) kinase pathway in human monocytes.
    Journal of medical microbiology, 2007, Volume: 56, Issue:Pt 2

    Topics: Bacterial Proteins; Butadienes; Cell Line; Chaperonin 60; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation; Helicobacter pylori; Humans; Imidazoles; Interleukin-8; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Models, Biological; Monocytes; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyridines; RNA, Messenger; RNA, Small Interfering; Toll-Like Receptor 2; Transcription, Genetic

2007
Corticotropin releasing hormone modulates endotoxin-induced inflammatory cytokine expression in human trophoblast cells.
    Placenta, 2007, Volume: 28, Issue:10

    Topics: Cells, Cultured; Corticotropin-Releasing Hormone; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Imidazoles; Interleukin-8; Lipopolysaccharides; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Pregnancy; Pyridines; Toll-Like Receptor 4; Trophoblasts; Tumor Necrosis Factor-alpha

2007
Effects of transcription factor activator protein-1 on interleukin-8 expression and enteritis in response to Clostridium difficile toxin A.
    Journal of molecular medicine (Berlin, Germany), 2007, Volume: 85, Issue:12

    Topics: Animals; Bacterial Toxins; Colon; Dimerization; Disease Models, Animal; Enterotoxins; Enzyme Activation; Epithelial Cells; Genes, ras; HT29 Cells; Humans; Ileitis; Imidazoles; Interleukin-8; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyridines; Time Factors; Transcription Factor AP-1; Transfection

2007
Cytokine-induced epithelial permeability changes are regulated by the activation of the p38 mitogen-activated protein kinase pathway in cultured Caco-2 cells.
    Shock (Augusta, Ga.), 2008, Volume: 29, Issue:4

    Topics: Caco-2 Cells; Cell Membrane Permeability; Cytokines; Enzyme-Linked Immunosorbent Assay; Epithelium; Humans; Imidazoles; Interferon-gamma; Interleukin-1; Interleukin-1beta; Interleukin-6; Interleukin-8; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha

2008
MD-2 controls bacterial lipopolysaccharide hyporesponsiveness in human intestinal epithelial cells.
    Life sciences, 2008, Feb-27, Volume: 82, Issue:9-10

    Topics: Anthracenes; Caco-2 Cells; Cell Line, Tumor; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Flow Cytometry; Gene Expression; HT29 Cells; Humans; Imidazoles; Interleukin-8; Intestines; Lipopolysaccharides; Lymphocyte Antigen 96; Mitogen-Activated Protein Kinases; Monocytes; NF-kappa B; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Toll-Like Receptor 4; Transfection

2008
The p38 mitogen-activated protein kinase pathway plays a critical role in PAR2-induced endothelial IL-8 production and leukocyte adhesion.
    Shock (Augusta, Ga.), 2008, Volume: 30, Issue:5

    Topics: Activating Transcription Factors; Blotting, Western; Cell Adhesion; Cells, Cultured; DNA, Complementary; Flavonoids; Flow Cytometry; Humans; Imidazoles; Indoles; Integrin alpha4beta1; Intercellular Adhesion Molecule-1; Interleukin-8; Leukocytes; Lymphocyte Function-Associated Antigen-1; Macrophage-1 Antigen; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptor, PAR-2; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Trypsin; Vascular Cell Adhesion Molecule-1

2008
Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-kappaB.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 296, Issue:2

    Topics: Anthracenes; Anti-Inflammatory Agents; Benzophenanthridines; Cell Line; Curcumin; Enzyme Activation; Epithelial Cells; Esophagus; Flavonoids; Humans; Hydrogen-Ion Concentration; Imidazoles; Interleukin-6; Interleukin-8; Mitogen-Activated Protein Kinases; Mucous Membrane; NF-kappa B; Peptides; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Telomerase; Time Factors; Transcription, Genetic; Up-Regulation

2009
Enzymatically hydrolyzed low-density lipoprotein modulates inflammatory responses in endothelial cells.
    Thrombosis and haemostasis, 2008, Volume: 100, Issue:6

    Topics: Cell Line; Endothelial Cells; Fatty Acids, Nonesterified; Humans; Hydrolysis; I-kappa B Proteins; Imidazoles; Inflammation; Interleukin-8; Lipoproteins, LDL; NF-KappaB Inhibitor alpha; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; Pyridines; Sterol Esterase; Time Factors; Transcription Factor AP-1; Transcription Factor RelA; Trypsin; Tumor Necrosis Factor-alpha

2008
Inhibition of NF-kappaB-dependent transcription by MKP-1: transcriptional repression by glucocorticoids occurring via p38 MAPK.
    The Journal of biological chemistry, 2009, Sep-25, Volume: 284, Issue:39

    Topics: Blotting, Western; Cell Line; Cell Line, Tumor; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Dual Specificity Phosphatase 1; Enzyme Inhibitors; Gene Expression Regulation; Glucocorticoids; Humans; Imidazoles; Interleukin-8; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transcription, Genetic; Tumor Necrosis Factor-alpha

2009
TLR3 in human eosinophils: functional effects and decreased expression during allergic rhinitis.
    International archives of allergy and immunology, 2010, Volume: 151, Issue:2

    Topics: Adult; Blood Cell Count; Bone Marrow Cells; CD11b Antigen; Cell Count; Cysteine Proteinase Inhibitors; Eosinophils; Female; Gene Expression; Humans; Imidazoles; Interleukin-4; Interleukin-5; Interleukin-8; Leupeptins; Male; Middle Aged; Neutrophils; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Poly I-C; Protein Kinase Inhibitors; Pyridines; Rhinitis, Allergic, Seasonal; Signal Transduction; Toll-Like Receptor 3; Virus Diseases; Young Adult

2010
C-reactive protein decreases interleukin-8 production in human endothelial progenitor cells by inhibition of p38 MAPK pathway.
    Chinese medical journal, 2009, Aug-20, Volume: 122, Issue:16

    Topics: C-Reactive Protein; Cells, Cultured; Endothelial Cells; Humans; Imidazoles; Interleukin-8; Male; p38 Mitogen-Activated Protein Kinases; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells

2009
Influence of NFkappaB inhibitors on IL-1beta-induced chemokine CXCL8 and -10 expression levels in intestinal epithelial cell lines: glucocorticoid ineffectiveness and paradoxical effect of PDTC.
    International journal of colorectal disease, 2010, Volume: 25, Issue:3

    Topics: Caco-2 Cells; Chemokine CXCL10; Dexamethasone; Epithelial Cells; Flavonoids; Gene Expression Regulation, Neoplastic; Genes, Reporter; Glucocorticoids; HT29 Cells; Humans; Imidazoles; Interleukin-1beta; Interleukin-8; Intestines; NF-kappa B; Nitriles; Pyridines; Pyrrolidines; Receptors, Glucocorticoid; RNA, Messenger; Sulfones; Thiocarbamates

2010
Novel p38 MAPK inhibitor ML3403 has potent anti-inflammatory activity in airway smooth muscle.
    European journal of pharmacology, 2010, Jun-10, Volume: 635, Issue:1-3

    Topics: Anti-Inflammatory Agents; Asthma; Cell Line; Gene Expression Regulation; Humans; Imidazoles; Interleukin-6; Interleukin-8; Isoenzymes; Muscle, Smooth; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Respiratory System; RNA, Messenger; Tumor Necrosis Factor-alpha

2010
Oxidized low-density lipoprotein increases interleukin-8 production in human gingival epithelial cell line Ca9-22.
    Journal of periodontal research, 2010, Volume: 45, Issue:4

    Topics: Cell Line, Tumor; Chemokine CCL2; Cholesterol 7-alpha-Hydroxylase; Dextran Sulfate; Dinoprostone; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Fucose; Gingiva; Humans; Imidazoles; Interleukin-1beta; Interleukin-8; Ketocholesterols; Lipoproteins, LDL; Mitogen-Activated Protein Kinases; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Periodontitis; Polysaccharides; Pyridines; Receptors, Scavenger; Sulfuric Acid Esters

2010
Proinflammatory effects of muramyldipeptide on human gingival fibroblasts.
    Journal of periodontal research, 2010, Volume: 45, Issue:2

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adult; Anthracenes; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chemokine CCL2; Chemokine CXCL10; Chemokine CXCL11; Chromones; Chronic Periodontitis; Enzyme Inhibitors; Female; Fibroblasts; Flavonoids; Gingiva; Humans; Imidazoles; Inflammation Mediators; Interferon-gamma; Interleukin-6; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Male; Middle Aged; Morpholines; Nod2 Signaling Adaptor Protein; Periodontal Attachment Loss; Periodontal Pocket; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Tumor Necrosis Factor-alpha

2010
Interleukin-1β regulates the migratory potential of MDAMB231 breast cancer cells through the hypoxia-inducible factor-1α.
    European journal of cancer (Oxford, England : 1990), 2010, Volume: 46, Issue:18

    Topics: Animals; Breast Neoplasms; Cell Communication; Cell Movement; Enzyme Inhibitors; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; Interleukin-1beta; Interleukin-8; Mice; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Neoplasm Transplantation; Pyridines; Transplantation, Heterologous

2010
Stimulation of pro-inflammatory responses by mebendazole in human monocytic THP-1 cells through an ERK signaling pathway.
    Archives of toxicology, 2011, Volume: 85, Issue:3

    Topics: Anthracenes; Antinematodal Agents; Cell Line, Tumor; Cells, Cultured; Chemokines; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; Imidazoles; Interleukin-8; Mebendazole; Mitogen-Activated Protein Kinases; Monocytes; Pyridines; Tumor Necrosis Factor-alpha

2011
Inhibitors of p38 and ERK1/2 MAPkinase and hydrogen sulphide block constitutive and IL-1β-induced IL-6 and IL-8 expression in the human chondrocyte cell line C-28/I2.
    Rheumatology international, 2012, Volume: 32, Issue:3

    Topics: Butadienes; Cell Line; Chondrocytes; Drug Antagonism; Enzyme Inhibitors; Gene Expression; Humans; Hydrogen Sulfide; Imidazoles; Interleukin-1beta; Interleukin-6; Interleukin-8; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyridines

2012
Enhancement of wound healing by human multipotent stromal cell conditioned medium: the paracrine factors and p38 MAPK activation.
    Cell transplantation, 2011, Volume: 20, Issue:5

    Topics: Animals; Antibodies; Cell Movement; Cells, Cultured; Chemokine CXCL1; Culture Media, Conditioned; Enzyme Activation; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Interleukin-6; Interleukin-8; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Neovascularization, Physiologic; p38 Mitogen-Activated Protein Kinases; Pyridines; RNA Interference; RNA, Small Interfering; Skin; Wound Healing

2011
Down-regulation of interleukin-16 in human mast cells HMC-1 by Clostridium difficile toxins A and B.
    Naunyn-Schmiedeberg's archives of pharmacology, 2011, Volume: 383, Issue:3

    Topics: Amino Acid Substitution; Bacterial Proteins; Bacterial Toxins; Cell Line; Down-Regulation; Enterotoxins; Gene Expression; Gene Expression Profiling; Glycosylation; Heme Oxygenase-1; Humans; Imidazoles; Interleukin-16; Interleukin-8; Mast Cells; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-kit; Pyridines; rac1 GTP-Binding Protein; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; rhoB GTP-Binding Protein; Up-Regulation; Urokinase-Type Plasminogen Activator

2011
Down-regulation of cytokine-induced interleukin-8 requires inhibition of p38 mitogen-activated protein kinase (MAPK) via MAPK phosphatase 1-dependent and -independent mechanisms.
    The Journal of biological chemistry, 2011, May-06, Volume: 286, Issue:18

    Topics: Anti-Inflammatory Agents; Cell Line; Dexamethasone; Dual Specificity Phosphatase 1; Enzyme Activation; Humans; Ibuprofen; Imidazoles; Interleukin-8; p38 Mitogen-Activated Protein Kinases; Pyridines; RNA Stability; RNA, Messenger

2011
High calcium, ATP, and poly(I:C) augment the immune response to β-glucan in normal human epidermal keratinocytes.
    The Journal of investigative dermatology, 2011, Volume: 131, Issue:11

    Topics: Adenosine Triphosphate; beta-Glucans; Calcium; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; Immunity, Innate; Interleukin-1alpha; Interleukin-6; Interleukin-8; Keratinocytes; Lectins, C-Type; Membrane Proteins; Nerve Tissue Proteins; p38 Mitogen-Activated Protein Kinases; Poly I-C; Pyridines; Signal Transduction

2011
IL-33 is induced by amyloid-β stimulation and regulates inflammatory cytokine production in retinal pigment epithelium cells.
    Inflammation, 2012, Volume: 35, Issue:2

    Topics: Amyloid beta-Peptides; Anthracenes; Butadienes; Cell Line; Humans; Imidazoles; Inflammation; Interleukin-1 Receptor-Like 1 Protein; Interleukin-1beta; Interleukin-33; Interleukin-6; Interleukin-8; Interleukins; JNK Mitogen-Activated Protein Kinases; Macular Degeneration; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Nitriles; Peptide Fragments; Pyridines; Receptors, Cell Surface; Retinal Pigment Epithelium; Sulfones; Tumor Necrosis Factor-alpha

2012
ICAM-1 and IL-8 are expressed by DEHP and suppressed by curcumin through ERK and p38 MAPK in human umbilical vein endothelial cells.
    Inflammation, 2012, Volume: 35, Issue:3

    Topics: Cell Line; Cell Survival; Curcumin; Diethylhexyl Phthalate; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-8; MAP Kinase Signaling System; Medicine, Chinese Traditional; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; RNA, Messenger

2012
Regulation of the p38 mitogen-activated protein kinase and dual-specificity phosphatase 1 feedback loop modulates the induction of interleukin 6 and 8 in cells infected with coronavirus infectious bronchitis virus.
    Virology, 2011, Nov-25, Volume: 420, Issue:2

    Topics: Animals; Cell Line, Tumor; Chlorocebus aethiops; Dual Specificity Phosphatase 1; Feedback, Physiological; Humans; Imidazoles; Infectious bronchitis virus; Interleukin-6; Interleukin-8; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Pyridines; RNA Interference; RNA, Small Interfering; Vero Cells

2011
Prostaglandin E2 enhances interleukin-8 production via EP4 receptor in human pulmonary microvascular endothelial cells.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Jan-15, Volume: 302, Issue:2

    Topics: Acute Lung Injury; Anthracenes; Butadienes; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Endothelial Cells; Humans; Imidazoles; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Lung; MAP Kinase Signaling System; Methyl Ethers; Microvessels; Naphthalenes; Neutrophils; Nitriles; p38 Mitogen-Activated Protein Kinases; Phenylbutyrates; Pyridines; Receptors, Prostaglandin E, EP4 Subtype; Respiratory Distress Syndrome; RNA, Messenger; Thionucleotides

2012
Dentin matrix protein-1 activates dental pulp fibroblasts.
    Journal of endodontics, 2012, Volume: 38, Issue:1

    Topics: Calcinosis; Cell Culture Techniques; Dental Pulp; Enzyme Inhibitors; Extracellular Matrix Proteins; Fibroblasts; Humans; Imidazoles; Inflammation Mediators; Interleukin-6; Interleukin-8; Lipopolysaccharides; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Pulpitis; Pyridines; Tooth, Impacted

2012
MKP-1: a negative feedback effector that represses MAPK-mediated pro-inflammatory signaling pathways and cytokine secretion in human airway smooth muscle cells.
    Cellular signalling, 2012, Volume: 24, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Bronchi; Diterpenes; Dual Specificity Phosphatase 1; Epoxy Compounds; Feedback, Physiological; Gene Expression Regulation; Histones; Humans; Imidazoles; Inflammation; Interleukin-8; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phenanthrenes; Primary Cell Culture; Promoter Regions, Genetic; Pyridines; Ribosomal Protein S6 Kinases, 90-kDa; RNA Stability; RNA, Small Interfering; Signal Transduction; Tumor Necrosis Factor-alpha

2012
miR-16 targets transcriptional corepressor SMRT and modulates NF-kappaB-regulated transactivation of interleukin-8 gene.
    PloS one, 2012, Volume: 7, Issue:1

    Topics: Anthracenes; Cells, Cultured; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Interleukin-8; Lipopolysaccharides; MAP Kinase Signaling System; MicroRNAs; NF-kappa B; Nuclear Receptor Co-Repressor 2; Pyridines; Transcription, Genetic; Transcriptional Activation; U937 Cells

2012
Regulation of interleukin-1alpha and tumor necrosis factor-alpha-induced interleukin-8 production by amnion-derived (WISH) cells.
    Clinical and experimental obstetrics & gynecology, 2012, Volume: 39, Issue:1

    Topics: Amnion; Butadienes; Cell Line; Enzyme Inhibitors; Fumonisins; Humans; Imidazoles; Interleukin 1 Receptor Antagonist Protein; Interleukin-1alpha; Interleukin-8; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nitriles; Pyridines; Sphingosine; Tumor Necrosis Factor-alpha

2012
Restoration of corticosteroid sensitivity by p38 mitogen activated protein kinase inhibition in peripheral blood mononuclear cells from severe asthma.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; Asthma; Cell Nucleus; Female; Humans; Imidazoles; Interleukin-8; Leukocytes, Mononuclear; Male; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phosphoserine; Protein Kinase Inhibitors; Protein Transport; Pyridines; Receptors, Glucocorticoid; Severity of Illness Index; U937 Cells

2012
A combined impedance and AlphaLISA-based approach to identify anti-inflammatory and barrier-protective compounds in human endothelium.
    Journal of biomolecular screening, 2013, Volume: 18, Issue:1

    Topics: Anti-Inflammatory Agents; Capillary Permeability; Cell Adhesion Molecules; Cyanobacteria; Cytokines; Depsipeptides; Electric Impedance; Endothelial Cells; Endothelium, Vascular; Gene Expression; High-Throughput Screening Assays; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Interleukin-8; Kinetics; Lung; Microvessels; Peptides, Cyclic; Pyridines; Reproducibility of Results; Transcriptional Activation; Tumor Necrosis Factor-alpha

2013
Secreted factors from human mast cells trigger inflammatory cytokine production by human airway smooth muscle cells.
    International archives of allergy and immunology, 2013, Volume: 160, Issue:1

    Topics: Asthma; Cell Line; Culture Media, Conditioned; Exosomes; Humans; Imidazoles; Immunoglobulin E; Inflammation; Interleukin-6; Interleukin-8; Mast Cells; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrimidines; Receptors, Fc; Respiratory System; RNA, Messenger; src-Family Kinases

2013
Interleukin-8 stimulates progesterone production via the MEK pathway in ovarian theca cells.
    Molecular and cellular biochemistry, 2013, Volume: 374, Issue:1-2

    Topics: Actins; Animals; Cattle; Cells, Cultured; Enzyme Inhibitors; Female; Flavonoids; Imidazoles; Interleukin-8; Mitogen-Activated Protein Kinase Kinases; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Progesterone; Pyridines; RNA, Messenger; Theca Cells

2013
[Inhibition of NHE1 down-regulates IL-8 expression and enhances p38 phosphorylation].
    Zhongguo shi yan xue ye xue za zhi, 2013, Volume: 21, Issue:1

    Topics: Cation Transport Proteins; Down-Regulation; Guanidines; Humans; Imidazoles; Interleukin-8; K562 Cells; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Sulfones

2013
Berberine counteracts enhanced IL-8 expression of AGS cells induced by evodiamine.
    Life sciences, 2013, Nov-19, Volume: 93, Issue:22

    Topics: Antineoplastic Agents, Phytogenic; Berberine; Cell Adhesion; Cell Cycle; Cell Movement; Cell Proliferation; Chemokines; Chemokines, CXC; Chromones; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Interleukin-8; Morpholines; Pyridines; Quinazolines; Signal Transduction; Stomach Neoplasms; Tumor Cells, Cultured

2013
Lipopolysaccharide-regulated production of bone sialoprotein and interleukin-8 in human periodontal ligament fibroblasts: the role of toll-like receptors 2 and 4 and the MAPK pathway.
    Journal of periodontal research, 2015, Volume: 50, Issue:2

    Topics: Adolescent; Calcification, Physiologic; Cell Culture Techniques; Cells, Cultured; Enzyme Inhibitors; Fibroblasts; Flavonoids; Gene Knockdown Techniques; Humans; Imidazoles; Integrin-Binding Sialoprotein; Interleukin-8; Lipopolysaccharides; MAP Kinase Signaling System; Periodontal Ligament; Porphyromonas gingivalis; Protein Kinase Inhibitors; Pyridines; RNA, Small Interfering; Toll-Like Receptor 2; Toll-Like Receptor 4; Young Adult

2015
Modulation of inflammation and pathology during dengue virus infection by p38 MAPK inhibitor SB203580.
    Antiviral research, 2014, Volume: 110

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Cell Line; Chemokine CCL5; Cricetinae; Culicidae; Dengue; Dengue Virus; Enzyme Inhibitors; Hematocrit; Humans; Imidazoles; Inflammation; Interleukin-8; Lymphopenia; Mice; p38 Mitogen-Activated Protein Kinases; Pyridines; Tumor Necrosis Factor-alpha

2014
IL-17 Enhances Chemotaxis of Primary Human B Cells during Asthma.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Adult; Asthma; B-Lymphocytes; Bronchi; Chemokine CXCL13; Chemotaxis; Enzyme Activation; Female; Humans; Imidazoles; Inflammation; Interleukin-17; Interleukin-8; Male; p38 Mitogen-Activated Protein Kinases; Pulmonary Disease, Chronic Obstructive; Pyridines; Receptors, Interleukin; Receptors, Interleukin-17; Th17 Cells

2014
MFG-E8 inhibits neutrophil migration through αvβ₃-integrin-dependent MAP kinase activation.
    International journal of molecular medicine, 2015, Volume: 36, Issue:1

    Topics: Antibodies, Neutralizing; Antigens, Surface; Cell Line, Tumor; Cell Movement; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Flow Cytometry; G-Protein-Coupled Receptor Kinase 2; HL-60 Cells; Humans; Imidazoles; Integrin alphaVbeta3; Interleukin-8; Milk Proteins; Neutrophil Infiltration; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptors, Interleukin-8B; Receptors, Vitronectin

2015
Effects of urban particulate matter with high glucose on human monocytes U937.
    Journal of applied toxicology : JAT, 2016, Volume: 36, Issue:4

    Topics: Enzyme Precursors; Gelatinases; Glucose; Humans; Imidazoles; Interleukin-1beta; Interleukin-8; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocytes; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Particulate Matter; Phosphorylation; Pyridines; Reactive Oxygen Species; U937 Cells; Up-Regulation

2016
Polyriboinosinic-polyribocytidylic acid facilitates interleukin-6, and interleukin-8 secretion in human dermal fibroblasts via the JAK/STAT3 and p38 MAPK signal transduction pathways.
    Cytokine, 2018, Volume: 102

    Topics: Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Humans; Imidazoles; Interleukin-6; Interleukin-8; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Poly I-C; Pyridines; Skin; STAT3 Transcription Factor; Tyrphostins

2018
Chlamydia trachomatis inhibits the production of pro-inflammatory cytokines in human PBMCs through induction of IL-10.
    Journal of medical microbiology, 2018, Volume: 67, Issue:2

    Topics: Butadienes; Chlamydia trachomatis; Cytokines; Enzyme Inhibitors; Humans; Imidazoles; Inflammation; Interleukin-10; Interleukin-6; Interleukin-8; Leukocytes, Mononuclear; Mitogen-Activated Protein Kinase 1; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyrazoles; Pyridines; Pyrimidines; Real-Time Polymerase Chain Reaction; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha; Up-Regulation

2018
Ginsenoside F1 suppresses astrocytic senescence-associated secretory phenotype.
    Chemico-biological interactions, 2018, Mar-01, Volume: 283

    Topics: Astrocytes; Cell Line; Cell Movement; Cell Proliferation; Cellular Senescence; DNA Repair; Enzyme-Linked Immunosorbent Assay; Ginsenosides; Humans; Imidazoles; Interleukin-6; Interleukin-8; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction

2018
Protective Effects of Calcitonin Gene-Related Peptide-Mediated p38 Mitogen-Activated Protein Kinase Pathway on Severe Acute Pancreatitis in Rats.
    Digestive diseases and sciences, 2019, Volume: 64, Issue:2

    Topics: Acute Disease; Amylases; Animals; Calcitonin Gene-Related Peptide; Cytokines; Disease Progression; Enzyme Inhibitors; Imidazoles; Inflammation; Interleukin-1beta; Interleukin-6; Interleukin-8; Lipase; Malondialdehyde; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pancreas; Pancreatitis; Peptide Fragments; Peroxidase; Pyridines; Random Allocation; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Signal Transduction; Tumor Necrosis Factor-alpha

2019
PSD-95 protects the pancreas against pathological damage through p38 MAPK signaling pathway in acute pancreatitis.
    Experimental biology and medicine (Maywood, N.J.), 2021, Volume: 246, Issue:13

    Topics: Acinar Cells; Animals; Cell Line; Disks Large Homolog 4 Protein; Imidazoles; Interleukin-6; Interleukin-8; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Pancreas; Pancreatitis; Protein Kinase Inhibitors; Pyridines; Rats; Tumor Necrosis Factor-alpha

2021