sb 203580 has been researched along with indomethacin in 13 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (indomethacin) | Trials (indomethacin) | Recent Studies (post-2010) (indomethacin) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 29,527 | 1,838 | 3,396 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 8 (61.54) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Agarwal, L; Chang, L; Chin, J; Croft, G; de Laszlo, SE; Fletcher, D; Forsyth, A; Frantz, B; Hacker, C; Hanlon, W; Harper, C; Kostura, M; Li, B; Luell, S; MacCoss, M; Mantlo, N; O'Keefe, SJ; O'Neill, EA; Orevillo, C; Pang, M; Parsons, J; Rolando, A; Sahly, Y; Sidler, K; Visco, D | 1 |
| Barlow, DJ; Ehrman, TM; Hylands, PJ | 1 |
| Clowes, AW; Daum, G; Deou, J; Kalmes, A | 1 |
| Coogan, AN; O'Connor, JJ; O'Neill, LA | 1 |
| Akkerman, JW; Gorter, G; van Willigen, G | 1 |
| Akkerman, JW; Bos, JL; Franke, B; Gorter, G; Hackeng, CM; Relou, IA; van Rijn , HJ | 1 |
| Gonzalez, A; Schmid, A; Schulz, I; Siegel, G; Sternfeld, L | 1 |
| Bradbury, CM; Gius, D; Horikoshi, N; Markovina, S; Rene, LM; Wei, SJ; Zoberi, I | 1 |
| Chan, ED; Cooper, AM; Fouts, D; Josephy, SI; Tse, HM | 1 |
| Hill, MA; Murphy, TV; Spurrell, BE | 1 |
| Catapano, AL; Inoue, H; Norata, GD; Pellegatta, F; Pirillo, A | 1 |
| Antonios, D; Gautier, JC; Lacour, S; Pallardy, M | 1 |
| Giacobbe, E; Leoncini, G; Signorello, MG | 1 |
13 other study(ies) available for sb 203580 and indomethacin
| Article | Year |
|---|---|
Pyrroles and other heterocycles as inhibitors of p38 kinase.
Topics: Animals; Arthritis, Experimental; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Furans; Humans; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyrazoles; Pyrroles; Rats | 1998 |
In silico search for multi-target anti-inflammatories in Chinese herbs and formulas.
Topics: Anti-Inflammatory Agents; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Databases, Factual; Drug Design; Drugs, Chinese Herbal; Enzyme Inhibitors; JNK Mitogen-Activated Protein Kinases; Medicine, Chinese Traditional; Models, Chemical; Models, Molecular; Molecular Conformation; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase 4 Inhibitors; Structure-Activity Relationship | 2010 |
Raf-1 is activated by the p38 mitogen-activated protein kinase inhibitor, SB203580.
Topics: 3T3 Cells; Animals; Aorta; Becaplermin; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Imidazoles; Indomethacin; MAP Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth; Oncogene Protein p21(ras); p38 Mitogen-Activated Protein Kinases; Papio; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins c-sis; Pyridines; Signal Transduction | 1999 |
The P38 mitogen-activated protein kinase inhibitor SB203580 antagonizes the inhibitory effects of interleukin-1beta on long-term potentiation in the rat dentate gyrus in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium-Calmodulin-Dependent Protein Kinases; Dentate Gyrus; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Flavonoids; Imidazoles; In Vitro Techniques; Indomethacin; Interleukin-1; Long-Term Potentiation; Male; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Perforant Pathway; Pyridines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1999 |
Thrombopoietin increases platelet sensitivity to alpha-thrombin via activation of the ERK2-cPLA2 pathway.
Topics: Animals; Blood Platelets; Carbazoles; Cattle; Cytoplasmic Granules; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Group IV Phospholipases A2; Humans; Imidazoles; Indoles; Indomethacin; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Aggregation; Protein Kinase C; Protein Processing, Post-Translational; Pyridines; Serotonin; Serum Albumin, Bovine; Thrombin; Thrombopoietin; Thromboxane A2 | 2000 |
Low-density lipoprotein activates the small GTPases Rap1 and Ral in human platelets.
Topics: Arachidonic Acid; Blood Platelet Disorders; Blood Platelets; Collagen; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Glutathione Transferase; Humans; Imidazoles; Indomethacin; Ligands; Lipoproteins, LDL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phosphorylation; Pyridines; ral GTP-Binding Proteins; rap1 GTP-Binding Proteins; Recombinant Fusion Proteins; Signal Transduction; Thrombin; Thromboxane A2; Time Factors | 2000 |
Arachidonic acid modulates the spatiotemporal characteristics of agonist-evoked Ca2+ waves in mouse pancreatic acinar cells.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Bombesin; Calcium Signaling; Cells, Cultured; Cholecystokinin; Enzyme Inhibitors; Flavonoids; Imidazoles; Indomethacin; Kinetics; Male; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pancreas; Phosphorylation; Pyridines | 2001 |
Indomethacin-induced radiosensitization and inhibition of ionizing radiation-induced NF-kappaB activation in HeLa cells occur via a mechanism involving p38 MAP kinase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Nucleus; Cell Survival; DNA; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; I-kappa B Proteins; Imidazoles; Indomethacin; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyridines; Radiation Tolerance; Sodium Salicylate; Sulindac; Transfection | 2001 |
Activation of the mitogen-activated protein kinase signaling pathway is instrumental in determining the ability of Mycobacterium avium to grow in murine macrophages.
Topics: Animals; Bone Marrow Cells; Cell Division; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Female; Growth Inhibitors; Imidazoles; Indomethacin; Interleukin-10; Interleukin-12; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Macrophages; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mycobacterium avium; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Tumor Necrosis Factor-alpha; Virulence | 2002 |
Intraluminal pressure stimulates MAPK phosphorylation in arterioles: temporal dissociation from myogenic contractile response.
Topics: Adenosine; Animals; Arterioles; Cyclooxygenase Inhibitors; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Imidazoles; In Vitro Techniques; Indomethacin; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Pressure; Pyridines; Rats; Rats, Sprague-Dawley; Time Factors; Vasoconstriction; Vasomotor System | 2003 |
Native LDL and oxidized LDL modulate cyclooxygenase-2 expression in HUVECs through a p38-MAPK, NF-kappaB, CRE dependent pathway and affect PGE2 synthesis.
Topics: Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Epoprostenol; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; Imidazoles; Immunoassay; Immunoblotting; Immunohistochemistry; Indomethacin; Lipoproteins, LDL; Membrane Proteins; NF-kappa B; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Thromboxane A2; Time Factors; Umbilical Veins | 2004 |
Acetaminophen and lipopolysaccharide act in synergy for the production of pro-inflammatory cytokines in murine RAW264.7 macrophages.
Topics: Acetaminophen; Animals; Anthracenes; Cell Line; Cytochrome P-450 CYP1A2 Inhibitors; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Imidazoles; Indomethacin; Interleukin-1beta; Lipopolysaccharides; Macrophages; MAP Kinase Kinase 1; MAP Kinase Kinase 4; Mice; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Pyridines; Signal Transduction; Theophylline; Tumor Necrosis Factor-alpha | 2009 |
Activation by 2-arachidonoylglycerol of platelet p38MAPK/cPLA2 pathway.
Topics: Apyrase; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Endocannabinoids; Glycerides; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Phospholipases A2, Cytosolic; Phosphorylation; Piperidines; Pyrazoles; Pyridines; Reactive Oxygen Species; Rimonabant; Signal Transduction | 2011 |