Compounds > sb 203580
Page last updated: 2024-09-05

sb 203580 and incb-018424

sb 203580 has been researched along with incb-018424 in 5 studies

Compound Research Comparison

Studies
(sb 203580)		Trials
(sb 203580)		Recent Studies (post-2010)
(sb 203580)		Studies
(incb-018424)		Trials
(incb-018424)		Recent Studies (post-2010) (incb-018424)
3,48941,1371,4871851,451

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)incb-018424 (IC50)
Cyclin-G-associated kinaseHomo sapiens (human)0.12
Tyrosine-protein kinase JAK2Homo sapiens (human)0.0573
Cytochrome P450 1A2Homo sapiens (human)0.0001
Tyrosine-protein kinase JAK1Homo sapiens (human)0.0327
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)0.0962
Tyrosine-protein kinase JAK3Homo sapiens (human)0.3547
AP2-associated protein kinase 1Homo sapiens (human)0.1
Histone deacetylase 6Homo sapiens (human)0.015

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Ciceri, P; Davis, MI; Herrgard, S; Hocker, M; Hunt, JP; Pallares, G; Treiber, DK; Wodicka, LM; Zarrinkar, PP1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Bharate, SB; Raghuvanshi, R1
Alzoubi, K; Briglia, M; Faggio, C; Fazio, A; Lang, F; Laufer, S1
Du, K; Li, Q; Liu, XZ; Zhou, M1

Other Studies

5 other study(ies) available for sb 203580 and incb-018424

ArticleYear
Comprehensive analysis of kinase inhibitor selectivity.
    Nature biotechnology, 2011, Oct-30, Volume: 29, Issue:11

    Topics: Catalysis; Drug Design; Enzyme Stability; High-Throughput Screening Assays; Humans; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Proteomics; Signal Transduction; Substrate Specificity

2011
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Drug Approval; Drug Repositioning; High-Throughput Screening Assays; Humans; Protein Kinase Inhibitors; SARS-CoV-2; United States; United States Food and Drug Administration; Virus Diseases

2022
Triggering of Suicidal Erythrocyte Death by Ruxolitinib.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 37, Issue:2

    Topics: Calcium; Cell Death; Cell Membrane; Cell Size; Erythrocytes; Humans; Imidazoles; MAP Kinase Signaling System; Nitriles; Oxidative Stress; Phosphatidylserines; Pyrazoles; Pyridines; Pyrimidines

2015
Chlamydia trachomatis inhibits the production of pro-inflammatory cytokines in human PBMCs through induction of IL-10.
    Journal of medical microbiology, 2018, Volume: 67, Issue:2

    Topics: Butadienes; Chlamydia trachomatis; Cytokines; Enzyme Inhibitors; Humans; Imidazoles; Inflammation; Interleukin-10; Interleukin-6; Interleukin-8; Leukocytes, Mononuclear; Mitogen-Activated Protein Kinase 1; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyrazoles; Pyridines; Pyrimidines; Real-Time Polymerase Chain Reaction; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha; Up-Regulation

2018