Compounds > sb 203580
Page last updated: 2024-09-05

sb 203580 and imatinib mesylate

sb 203580 has been researched along with imatinib mesylate in 8 studies

Compound Research Comparison

Studies
(sb 203580)		Trials
(sb 203580)		Recent Studies (post-2010)
(sb 203580)		Studies
(imatinib mesylate)		Trials
(imatinib mesylate)		Recent Studies (post-2010) (imatinib mesylate)
3,48941,13711,4779605,773

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)imatinib mesylate (IC50)
Tyrosine-protein kinase ABL1Homo sapiens (human)0.31
Mast/stem cell growth factor receptor KitHomo sapiens (human)0.1

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's2 (25.00)29.6817
2010's3 (37.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Bharate, SB; Raghuvanshi, R1
Coffey, ET; Courtney, MJ1
Dolezel, P; Frydrych, I; Mlejnek, P1
Chang, SP; Chen, YC; Lee, WR; Shen, SC; Yang, LL1
Huang, B; Khatibi, N; Ma, Q; Rolland, W; Suzuki, H; Tang, J; Zhang, JH1
Chang, GQ; Hu, RH; Jin, WN; Li, QH; Lin, YN; Pang, TX; Ru, YX; Wang, J1
Gao, F; Jia, X; Li, Z; Peng, X; Tian, X; Zhang, A1

Other Studies

8 other study(ies) available for sb 203580 and imatinib mesylate

ArticleYear
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Drug Approval; Drug Repositioning; High-Throughput Screening Assays; Humans; Protein Kinase Inhibitors; SARS-CoV-2; United States; United States Food and Drug Administration; Virus Diseases

2022
The mechanism of Ara-C-induced apoptosis of differentiating cerebellar granule neurons.
    The European journal of neuroscience, 1999, Volume: 11, Issue:3

    Topics: Androstadienes; Animals; Antimetabolites, Antineoplastic; Apoptosis; Benzamides; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Differentiation; Cell Survival; Cerebellum; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cytarabine; Enzyme Inhibitors; Flavonoids; Imatinib Mesylate; Imidazoles; Mitogen-Activated Protein Kinase 12; Mitogen-Activated Protein Kinases; Neurons; Piperazines; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Kinases; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Purines; Pyridines; Pyrimidines; Rats; Roscovitine; Signal Transduction; Stress, Physiological; Wortmannin

1999
Cyclosporin A sensitises Bcr-Abl positive cells to imatinib mesylate independently of P-glycoprotein expression.
    Toxicology in vitro : an international journal published in association with BIBRA, 2009, Volume: 23, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzamides; Cyclosporine; Extracellular Signal-Regulated MAP Kinases; Fusion Proteins, bcr-abl; Glutathione; Glutathione Disulfide; Humans; Imatinib Mesylate; Imidazoles; K562 Cells; Piperazines; Pyridines; Pyrimidines

2009
Imatinib mesylate induction of ROS-dependent apoptosis in melanoma B16F0 cells.
    Journal of dermatological science, 2011, Volume: 62, Issue:3

    Topics: Animals; Anthracenes; Antineoplastic Agents; Apoptosis; Benzamides; Flavonoids; Flow Cytometry; Imatinib Mesylate; Imidazoles; Melanoma, Experimental; Membrane Potentials; Mice; Mitochondria; Piperazines; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Reactive Oxygen Species

2011
PDGFR-α inhibition preserves blood-brain barrier after intracerebral hemorrhage.
    Annals of neurology, 2011, Volume: 70, Issue:6

    Topics: Animals; Antibodies; Basal Ganglia; Benzamides; Blood Transfusion, Autologous; Blood-Brain Barrier; Brain Edema; Cerebral Hemorrhage; Disease Models, Animal; Enzyme Inhibitors; Evans Blue; Gene Expression Regulation; Imatinib Mesylate; Imidazoles; Metalloendopeptidases; Mice; p38 Mitogen-Activated Protein Kinases; Piperazines; Pyridines; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction; Thrombin; Time Factors

2011
[Increasing sensitivity of leukemia cells to imatinib by inhibiting NHE1 and p38MAPK signaling pathway].
    Zhongguo shi yan xue ye xue za zhi, 2012, Volume: 20, Issue:6

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzamides; Cation Transport Proteins; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Leukemic; Humans; Imatinib Mesylate; Imidazoles; K562 Cells; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Piperazines; Pyridines; Pyrimidines; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers

2012
Activation of spinal PDGFRβ in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats.
    Journal of neurochemistry, 2021, Volume: 158, Issue:2

    Topics: Adenine; Animals; Autophagy; Drug Tolerance; Imatinib Mesylate; Imidazoles; Injections, Spinal; Male; MAP Kinase Signaling System; Microglia; Minocycline; Morphine; Narcotics; Neurons; p38 Mitogen-Activated Protein Kinases; Pain Measurement; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Platelet-Derived Growth Factor beta

2021