Page last updated: 2024-09-05

sb 203580 and hc-067047

sb 203580 has been researched along with hc-067047 in 2 studies

Compound Research Comparison

Studies (sb 203580)	Trials (sb 203580)	Recent Studies (post-2010) (sb 203580)	Studies (hc-067047)	Trials (hc-067047)	Recent Studies (post-2010) (hc-067047)
3,489	4	1,137	69	0	66

Protein Interaction Comparison

Protein	Taxonomy	hc-067047 (IC50)
Transient receptor potential cation channel subfamily V member 4	Mus musculus (house mouse)	0.017
Transient receptor potential cation channel subfamily V member 4	Rattus norvegicus (Norway rat)	0.1487
Transient receptor potential cation channel subfamily V member 4	Homo sapiens (human)	0.0449

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1
Chen, L; Du, Y; Hong, Z; Jie, P; Li, Y; Lin, L; Tian, Y; Zhou, L	1

Other Studies

2 other study(ies) available for sb 203580 and hc-067047

Article	Year
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013
Activation of transient receptor potential vanilloid 4 induces apoptosis in hippocampus through downregulating PI3K/Akt and upregulating p38 MAPK signaling pathways. Cell death & disease, 2015, Jun-04, Volume: 6 Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Down-Regulation; Enzyme Activation; Hippocampus; Imidazoles; Infarction, Middle Cerebral Artery; JNK Mitogen-Activated Protein Kinases; Leucine; Male; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Morpholines; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyridines; Pyrroles; Sulfonamides; TRPV Cation Channels	2015

Article

Year

Identification of potent Yes1 kinase inhibitors using a library screening approach.

Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013

Activation of transient receptor potential vanilloid 4 induces apoptosis in hippocampus through downregulating PI3K/Akt and upregulating p38 MAPK signaling pathways.

Cell death & disease, 2015, Jun-04, Volume: 6

Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Down-Regulation; Enzyme Activation; Hippocampus; Imidazoles; Infarction, Middle Cerebral Artery; JNK Mitogen-Activated Protein Kinases; Leucine; Male; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Morpholines; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyridines; Pyrroles; Sulfonamides; TRPV Cation Channels

2015