sb 203580 has been researched along with glutamic acid in 13 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (glutamic acid) | Trials (glutamic acid) | Recent Studies (post-2010) (glutamic acid) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 41,757 | 452 | 12,876 |
| Protein | Taxonomy | sb 203580 (IC50) | glutamic acid (IC50) |
|---|---|---|---|
| Chain A, GLUTAMATE RECEPTOR SUBUNIT 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain A, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain B, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | 0.0057 | |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor 1 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 2 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 3 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.38 | |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | 207 | |
| Glutamate receptor 4 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.1533 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 8 (61.54) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Fiebich, BL; Goldsteins, G; Keinanen, R; Koistinaho, J; Tikka, T | 1 |
| Barry, C; Brady, M; Kelly, A; Loscher, CE; Lynch, MA; Mills, KH; Nolan, Y; Vereker, E | 1 |
| Armendariz-Borunda, J; Beas-Zárate, C; Feria-Velasco, A; Rivera-Cervantes, MC; Torres, JS | 1 |
| Papp, L; Sperlágh, B; Vizi, ES | 1 |
| Kondo, A; Matsuda, T; Togari, A; Tsunashima, Y | 1 |
| O'Connor, JJ; Pickering, M; Watters, O | 1 |
| Sugiura, H; Yamagata, K; Yasuda, A | 1 |
| Bae, DW; Choi, BT; Choi, YW; Hong, JW; Jang, JY; Kim, HN; Kim, YR; Park, SJ; Shin, HK | 1 |
| Beas-Zárate, C; Camins, A; Castañeda-Arellano, R; Castro-Torres, RD; Feria y Velasco, AI; Gudiño-Cabrera, G; Rivera-Cervantes, MC | 1 |
| Al-Hasani, R; Bloodgood, DW; Bruchas, MR; Crowley, NA; Hardaway, JA; Kash, TL; Kendra, AM; Krashes, MJ; Lowell, BB; McCall, JG; McCall, NM; Schools, ZL; Whistler, JL; Yu, W | 1 |
| Chen, CH; Chen, NF; Chen, WF; Feng, CW; Huang, SY; Sung, CS; Wen, ZH; Wong, CS | 1 |
| Gong, JX; Hu, YY; Li, L; Li, WB; Lou, N; Qi, J; Su, AC; Xian, XH; Zhang, JG; Zhang, LY; Zhang, M; Zhang, MY; Zhao, CC; Zhao, H | 1 |
| Chen, Q; Chen, Y; Feng, Z; Huang, H; Peng, Y; Wang, J; Xu, Z; Zeng, J; Zhang, H; Zhang, J; Zhou, X | 1 |
13 other study(ies) available for sb 203580 and glutamic acid
| Article | Year |
|---|---|
Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia.
Topics: Animals; Anti-Bacterial Agents; Cell Death; Cell Division; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acids; Glutamic Acid; Hydro-Lyases; Imidazoles; Kainic Acid; Microglia; Minocycline; Mitogen-Activated Protein Kinases; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Wistar; Spinal Cord | 2001 |
Activation of p38 plays a pivotal role in the inhibitory effect of lipopolysaccharide and interleukin-1 beta on long term potentiation in rat dentate gyrus.
Topics: Animals; Caspase 1; Dentate Gyrus; Entorhinal Cortex; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Hippocampus; Imidazoles; Immunohistochemistry; Interleukin-1; Lipopolysaccharides; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Wistar | 2003 |
NMDA and AMPA receptor expression and cortical neuronal death are associated with p38 in glutamate-induced excitotoxicity in vivo.
Topics: Activating Transcription Factor 2; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Carrier Proteins; Cell Death; Cell Survival; Cerebral Cortex; Cyclic AMP Response Element-Binding Protein; Densitometry; Drug Interactions; Enzyme Inhibitors; Female; Gene Expression Regulation, Developmental; Glutamic Acid; Humans; Hyaluronan Receptors; Imidazoles; In Situ Nick-End Labeling; Male; Mitochondrial Proteins; Mitogen-Activated Protein Kinases; Neurons; p38 Mitogen-Activated Protein Kinases; Pregnancy; Protein Subunits; Pyridines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors | 2004 |
P2X7 receptor mediated phosphorylation of p38MAP kinase in the hippocampus.
Topics: Animals; Blotting, Western; Flavonoids; Glutamic Acid; Hippocampus; Imidazoles; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Purinergic P2 Receptor Agonists; Pyridines; Receptors, Purinergic P2; Receptors, Purinergic P2X7 | 2007 |
Inhibitory effect of vitamin K(2) on interleukin-1beta-stimulated proliferation of human osteoblasts.
Topics: Adult; Anticoagulants; Bone Neoplasms; Cell Line; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Flavonoids; Glutamic Acid; Humans; Imidazoles; Interleukin-1; Interleukin-1beta; Male; Mitogen-Activated Protein Kinase Kinases; Nitrobenzenes; Osteoblasts; Osteocalcin; Osteosarcoma; p38 Mitogen-Activated Protein Kinases; Pregnane X Receptor; Protein Kinase Inhibitors; Pyridines; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; Rifampin; RNA, Messenger; Sulfonamides; Vitamin K; Vitamins; Warfarin; Young Adult | 2010 |
Preconditioning effects of tumor necrosis factor-α and glutamate on calcium dynamics in rat organotypic hippocampal cultures.
Topics: Animals; Animals, Newborn; Calcium; Cell Death; Cell Survival; Drug Administration Schedule; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Imidazoles; Male; Nonlinear Dynamics; Organ Culture Techniques; Propidium; Pyridines; Rats; Rats, Wistar; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha; Valine | 2011 |
[Mechanism in diminishing dendritic spines following excessive nerve excitation].
Topics: Brain; Cadherins; Dendritic Spines; Drug Design; Endocytosis; Epilepsy; Glutamic Acid; Humans; Imidazoles; Memory Disorders; p38 Mitogen-Activated Protein Kinases; Protein Binding; Protein Kinases; Protocadherins; Pyridines; Synapses | 2012 |
Neuroprotective effects of a novel single compound 1-methoxyoctadecan-1-ol isolated from Uncaria sinensis in primary cortical neurons and a photothrombotic ischemia model.
Topics: Animals; Brain Ischemia; Calpain; Cerebral Cortex; Disease Models, Animal; Enzyme Inhibitors; Fatty Alcohols; Gene Expression Regulation; Glutamic Acid; Imidazoles; Mice; Neurons; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Photochemical Processes; Primary Cell Culture; Protein Tyrosine Phosphatases, Non-Receptor; Pyridines; Rats; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Thrombosis; Uncaria | 2014 |
P38 MAPK inhibition protects against glutamate neurotoxicity and modifies NMDA and AMPA receptor subunit expression.
Topics: Animals; Glutamic Acid; Hippocampus; Imidazoles; MAP Kinase Signaling System; Neurons; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Subunits; Pyridines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2015 |
Dynorphin Controls the Gain of an Amygdalar Anxiety Circuit.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amygdala; Animals; Anxiety; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Channelrhodopsins; Dynorphins; Evoked Potentials; Glutamic Acid; Imidazoles; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microscopy, Fluorescence; p38 Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Pyridines; Receptors, Opioid, kappa; Septal Nuclei | 2016 |
Potentiation of spinal glutamatergic response in the neuron-glia interactions underlies the intrathecal IL-1β-induced thermal hyperalgesia in rats.
Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hot Temperature; Hyperalgesia; Imidazoles; Interleukin-1beta; Male; Microglia; Minocycline; Neurons; Nitric Oxide; Nociceptive Pain; Phosphorylation; Pyridines; Random Allocation; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2017 |
The mechanism of GLT-1 mediating cerebral ischemic injury depends on the activation of p38 MAPK.
Topics: Animals; Astrocytes; Brain Ischemia; CA1 Region, Hippocampal; Cell Death; Coculture Techniques; Excitatory Amino Acid Transporter 2; Glucose; Glutamic Acid; Hippocampus; Imidazoles; Male; MAP Kinase Signaling System; Neurons; Oxygen; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Wistar; Signal Transduction | 2019 |
Inhibition of p38 MAPK regulates epileptic severity by decreasing expression levels of A1R and ENT1.
Topics: Animals; Anticonvulsants; Brain; Epilepsy; Equilibrative Nucleoside Transporter 1; Glutamic Acid; Hippocampus; Imidazoles; Male; Neurons; p38 Mitogen-Activated Protein Kinases; Pilocarpine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Seizures; Signal Transduction; Status Epilepticus | 2020 |