Page last updated: 2024-09-05

sb 203580 and gdc 0449

sb 203580 has been researched along with gdc 0449 in 1 studies

Compound Research Comparison

Studies
(sb 203580)
Trials
(sb 203580)
Recent Studies (post-2010)
(sb 203580)
Studies
(gdc 0449)
Trials
(gdc 0449)
Recent Studies (post-2010) (gdc 0449)
3,48941,13766668611

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)gdc 0449 (IC50)
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.02
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.02
Smoothened homologMus musculus (house mouse)0.07
Sonic hedgehog proteinHomo sapiens (human)0.8825
Sonic hedgehog proteinMus musculus (house mouse)0.0077
Smoothened homologHomo sapiens (human)0.0222
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.4

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1

Other Studies

1 other study(ies) available for sb 203580 and gdc 0449

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013