sb 203580 has been researched along with fulvestrant in 7 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (fulvestrant) | Trials (fulvestrant) | Recent Studies (post-2010) (fulvestrant) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 2,712 | 207 | 1,196 |
| Protein | Taxonomy | sb 203580 (IC50) | fulvestrant (IC50) |
|---|---|---|---|
| Estrogen receptor | Homo sapiens (human) | 0.0061 | |
| Estrogen receptor | Rattus norvegicus (Norway rat) | 0.0059 | |
| Progesterone receptor | Homo sapiens (human) | 0.0002 | |
| Steroid hormone receptor ERR1 | Homo sapiens (human) | 0.002 | |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | 0.006 | |
| Estrogen receptor beta | Homo sapiens (human) | 0.0104 | |
| Bile acid receptor | Homo sapiens (human) | 0.79 | |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | Homo sapiens (human) | 2.6 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Cho, S; Kim, B; Kim, J; Kwon, S; Lee, S; Park, S; Won, KJ | 1 |
| Glusa, E; Gust, R; Moritz, A; Pertz, HH; Radtke, OA | 1 |
| Cheng, J; Shapiro, DJ; Yu, DV; Zhou, JH | 1 |
| Hatae, J; Honda, A; Inoue, R; Lin, H; Takami, N | 1 |
| Baird, AW; Collins, D; Hogan, AM; Sheehan, K; Winter, DC; Zierau, O | 1 |
| Ding, Z; Duan, H; Ge, W; Hu, J; Jiang, Y; Lv, J; Xiao, L; Zhang, Y; Zhao, X | 1 |
7 other study(ies) available for sb 203580 and fulvestrant
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Tamoxifen induces vasorelaxation via inhibition of mitogen-activated protein kinase in rat aortic smooth muscle.
Topics: Animals; Aorta; Blotting, Western; Endothelin-1; Estradiol; Fulvestrant; Imidazoles; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Pyridines; Rats; Tamoxifen; Vasodilation | 2003 |
Characterisation of the relaxant response to raloxifene in porcine coronary arteries.
Topics: Animals; Calcium; Calcium Channels; Coronary Vessels; Estradiol; Fulvestrant; Imidazoles; In Vitro Techniques; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Swine; Vasodilation | 2006 |
Delayed and persistent ERK1/2 activation is required for 4-hydroxytamoxifen-induced cell death.
Topics: Caspase 3; Caspase 9; Cell Death; Enzyme Activation; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Flavonoids; Fulvestrant; HeLa Cells; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptors, Estrogen; Tamoxifen; Time Factors | 2007 |
17beta-Estradiol-induced enhancement of estrogen receptor biosynthesis via MAPK pathway in mouse skeletal muscle myoblasts.
Topics: Animals; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Flavonoids; Fulvestrant; Imidazoles; Mice; Mitogen-Activated Protein Kinase Kinases; Models, Animal; Muscle, Skeletal; Myoblasts, Skeletal; Pyridines; Receptors, Estrogen; Signal Transduction; Tamoxifen | 2009 |
Rapid effects of phytoestrogens on human colonic smooth muscle are mediated by oestrogen receptor beta.
Topics: Butadienes; Colon; Cycloheximide; Estradiol; Estrogen Receptor beta; Fulvestrant; Humans; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitriles; Phytoestrogens; Pyridines; Reproducibility of Results; Tissue Survival | 2010 |
17β-estradiol protects sheep oviduct epithelial cells against lipopolysaccharide-induced inflammation in vitro.
Topics: Animals; Aromatase; Cytokines; Epithelial Cells; Estradiol; Female; Fulvestrant; Gene Expression Regulation; Imidazoles; Inflammation; Lipopolysaccharides; Mitogen-Activated Protein Kinases; NF-kappa B; Oviducts; Phosphatidylinositol 3-Kinases; Phosphorylation; Protective Agents; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyridines; Receptors, Estrogen; Receptors, G-Protein-Coupled; RNA, Messenger; Sheep; Signal Transduction | 2020 |