Page last updated: 2024-09-05

sb 203580 and fenofibrate

sb 203580 has been researched along with fenofibrate in 4 studies

Compound Research Comparison

Studies
(sb 203580)
Trials
(sb 203580)
Recent Studies (post-2010)
(sb 203580)
Studies
(fenofibrate)
Trials
(fenofibrate)
Recent Studies (post-2010) (fenofibrate)
3,48941,1373,0585291,354

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)fenofibrate (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)2.371
Adenosine receptor A3Homo sapiens (human)5.701
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)5.701
5-hydroxytryptamine receptor 2AHomo sapiens (human)2.118
5-hydroxytryptamine receptor 2CHomo sapiens (human)2.371
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)5.701
Sodium-dependent dopamine transporter Homo sapiens (human)8.633
Peroxisome proliferator-activated receptor alphaHomo sapiens (human)1
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)5.1

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Fujisaki, K; Itoh, Y; Kubota, T; Oishi, R; Yano, T1
Calin, M; Dragomir, E; Gan, AM; Koenen, RR; Manduteanu, I; Simionescu, M; Stan, D; Weber, C1
Chen, TH; Chiou, YL; Huang, YC; Li, TT; Liu, KC; Liu, LL; Yang, CH1

Other Studies

4 other study(ies) available for sb 203580 and fenofibrate

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Fenofibrate induces apoptotic injury in cultured human hepatocytes by inhibiting phosphorylation of Akt.
    Apoptosis : an international journal on programmed cell death, 2005, Volume: 10, Issue:2

    Topics: Androstadienes; Annexin A5; Apoptosis; Caspases; Cell Line; Cell Membrane; Cell Nucleus; Cell Survival; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fenofibrate; Hepatocytes; Humans; Hydroxyeicosatetraenoic Acids; Hypolipidemic Agents; Imidazoles; In Situ Nick-End Labeling; Insulin; Microscopy, Fluorescence; Phosphatidylinositol 3-Kinases; Phosphatidylserines; Phosphorylation; PPAR alpha; Propidium; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Wortmannin

2005
High glucose conditions induce upregulation of fractalkine and monocyte chemotactic protein-1 in human smooth muscle cells.
    Thrombosis and haemostasis, 2008, Volume: 100, Issue:6

    Topics: Cell Adhesion; Cells, Cultured; Chemokine CCL2; Chemokine CX3CL1; Clofibrate; Fenofibrate; Flavonoids; Glucose; Humans; I-kappa B Proteins; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Monocytes; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; NF-kappa B; NF-KappaB Inhibitor alpha; p38 Mitogen-Activated Protein Kinases; Phosphorylation; PPAR alpha; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; Pyridines; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Transcription Factor AP-1; Up-Regulation

2008
Fenofibrate suppresses melanogenesis in B16-F10 melanoma cells via activation of the p38 mitogen-activated protein kinase pathway.
    Chemico-biological interactions, 2013, Oct-05, Volume: 205, Issue:3

    Topics: Blotting, Western; Cell Line, Tumor; Cell Survival; Fenofibrate; Humans; Imidazoles; MAP Kinase Signaling System; Melanins; Melanoma, Experimental; Microphthalmia-Associated Transcription Factor; Oxazoles; PPAR alpha; Pyridines; Real-Time Polymerase Chain Reaction; RNA; Tyrosine

2013