Page last updated: 2024-09-05

sb 203580 and dinoprost

sb 203580 has been researched along with dinoprost in 11 studies

Compound Research Comparison

Studies
(sb 203580)
Trials
(sb 203580)
Recent Studies (post-2010)
(sb 203580)
Studies
(dinoprost)
Trials
(dinoprost)
Recent Studies (post-2010) (dinoprost)
3,48941,13711,5549401,936

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)dinoprost (IC50)
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.0025
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.0713
Prostaglandin G/H synthase 1Homo sapiens (human)0.14
Prostaglandin E2 receptor EP1 subtypeHomo sapiens (human)0.3
Prostaglandin G/H synthase 2Homo sapiens (human)0.14
Prostaglandin E2 receptor EP4 subtypeHomo sapiens (human)4.2
Prostaglandin F2-alpha receptorBos taurus (cattle)0.14
Prostaglandin F2-alpha receptorHomo sapiens (human)0.0139
Prostaglandin E2 receptor EP3 subtypeHomo sapiens (human)0.216
Prostaglandin D2 receptorHomo sapiens (human)4.5
Solute carrier organic anion transporter family member 2B1Rattus norvegicus (Norway rat)0.287

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (90.91)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kawamura, H; Kozawa, O; Uematsu, T1
Kawamura, H; Kozawa, O; Matsuno, H; Uematsu, T1
Aihara, Y; Arai, M; Kanai, H; Kanda, T; Kurabayashi, M; Nagai, R; Sekiguchi, K; Tanaka, T; Yokoyama, T1
Abdel-Latif, AA; Gao, G; Yousufzai, SY1
Christoffersen, T; Hege Thoresen, G; Nilssen, LS; Sandnes, D1
Benati, D; Berton, G; Gaino, S; Minuz, P; Ortolani, R; Santonastaso, CL; Tommasoli, RM; Zancanaro, C; Zuliani, V1
Demetris, AJ; Han, C; Lunz, JG; Michalopoulos, G; Shelhamer, JH; Wu, T1
Guzeloglu, A; Michel, F; Subramaniam, P; Thatcher, WW1
Abramson, SB; Apsel, B; Chan, ES; Chang, LF; Clancy, R; Dinsell, V; Gomez, P; Marjanovic, N; Pillinger, MH; Tolani, SN1
Kawakami, T; Olsson, T; Yucel-Lindberg, T1
Baumann, S; Böhme, A; Kohajda, T; Lehmann, I; Mögel, I; Simon, JC; von Bergen, M1

Other Studies

11 other study(ies) available for sb 203580 and dinoprost

ArticleYear
Sphingosine 1-phosphate amplifies phosphoinositide hydrolysis stimulated by prostaglandin f2 alpha in osteoblasts: involvement of p38MAP kinase.
    Prostaglandins, leukotrienes, and essential fatty acids, 2000, Volume: 62, Issue:6

    Topics: Analysis of Variance; Animals; Blotting, Western; Cells, Cultured; Dinoprost; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Hydrolysis; Imidazoles; Lysophospholipids; Mice; Mitogen-Activated Protein Kinases; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositols; Pyridines; Sphingosine; Tumor Necrosis Factor-alpha; Type C Phospholipases

2000
p38 MAP kinase is involved in the signalling of sphingosine in osteoblasts: sphingosine inhibits prostaglandin F(2alpha)-induced phosphoinositide hydrolysis.
    Cellular signalling, 2000, Volume: 12, Issue:7

    Topics: Animals; Blotting, Western; Dinoprost; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Hydrolysis; Imidazoles; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositols; Phosphorylation; Pyridines; Signal Transduction; Sodium Fluoride; Sphingosine; Time Factors

2000
Induction of VEGF gene transcription by IL-1 beta is mediated through stress-activated MAP kinases and Sp1 sites in cardiac myocytes.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:11

    Topics: Animals; Animals, Newborn; Cells, Cultured; Dactinomycin; Dinoprost; Endothelial Growth Factors; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Genistein; Heart; Imidazoles; Interleukin-1; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Lymphokines; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Myocardium; Naphthalenes; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Wistar; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Sp1 Transcription Factor; Stress, Physiological; Transcription, Genetic; Transfection; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2000
Mitogen-activated protein kinase inhibitors suppress prostaglandin F(2alpha)-induced myosin-light chain phosphorylation and contraction in iris sphincter smooth muscle.
    European journal of pharmacology, 2000, Oct-27, Volume: 407, Issue:1-2

    Topics: Animals; Carbachol; Cats; Dinoprost; Enzyme Inhibitors; Flavonoids; Imidazoles; Iris; Miotics; Mitogen-Activated Protein Kinases; Muscle Contraction; Muscle, Smooth; Myosin Light Chains; Oxytocics; Phosphorylation; Pyridines

2000
Differential role of MAP kinases in stimulation of hepatocyte growth by EGF and G-protein-coupled receptor agonists.
    Biochemical and biophysical research communications, 2002, Mar-01, Volume: 291, Issue:3

    Topics: Angiotensin II; Animals; Cell Division; Dinoprost; DNA; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Hepatocytes; Heterotrimeric GTP-Binding Proteins; Imidazoles; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Norepinephrine; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Wistar; Receptors, Cell Surface; Vasopressins

2002
Functional role of p38 mitogen activated protein kinase in platelet activation induced by a thromboxane A2 analogue and by 8-iso-prostaglandin F2alpha.
    Thrombosis and haemostasis, 2002, Volume: 87, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Actin Cytoskeleton; Actins; Adult; Antigens, CD; Blood Platelets; Cell Size; Cytochalasin D; Dinoprost; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; F2-Isoprostanes; Humans; Imidazoles; Integrin beta3; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Microscopy, Electron, Scanning; Mitogen-Activated Protein Kinases; P-Selectin; p38 Mitogen-Activated Protein Kinases; Platelet Activation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Pseudopodia; Pyridines; Stilbenes; Syk Kinase; Thromboxane A2

2002
Involvement of 85-kd cytosolic phospholipase A(2) and cyclooxygenase-2 in the proliferation of human cholangiocarcinoma cells.
    Hepatology (Baltimore, Md.), 2002, Volume: 36, Issue:2

    Topics: Arachidonic Acids; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Division; Cholangiocarcinoma; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytosol; Dinoprost; Dinoprostone; Enzyme Inhibitors; Flavonoids; Hepatocyte Growth Factor; Humans; Imidazoles; Interleukin-6; Isoenzymes; Membrane Proteins; Mitogen-Activated Protein Kinases; Nitrobenzenes; Organophosphonates; Phospholipases A; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Pyridines; Sulfonamides; Tumor Cells, Cultured

2002
Interferon-tau induces degradation of prostaglandin H synthase-2 messenger RNA in bovine endometrial cells through a transcription-dependent mechanism.
    Biology of reproduction, 2004, Volume: 71, Issue:1

    Topics: Animals; Cattle; Cyclooxygenase 2; Dinoprost; Drug Synergism; Endometrium; Enzyme Inhibitors; Female; Imidazoles; Interferon Type I; Isoenzymes; p38 Mitogen-Activated Protein Kinases; Phorbol 12,13-Dibutyrate; Phosphorylation; Pregnancy Proteins; Prostaglandin-Endoperoxide Synthases; Protein Processing, Post-Translational; Pyridines; Recombinant Proteins; RNA, Messenger; Transcription, Genetic

2004
Regulation of metalloproteinases and NF-kappaB activation in rabbit synovial fibroblasts via E prostaglandins and Erk: contrasting effects of nabumetone and 6MNA.
    British journal of pharmacology, 2004, Volume: 142, Issue:6

    Topics: Alprostadil; Analysis of Variance; Animals; Butadienes; Butanones; Cell Line; Cell Survival; Cyclooxygenase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Imidazoles; Interleukin-1; Matrix Metalloproteinase 1; Metalloendopeptidases; Nabumetone; Naphthaleneacetic Acids; NF-kappa B; Nitric Oxide; Nitriles; Phosphorylation; Prostaglandins E; Pyridines; Rabbits; Synovial Membrane; Tumor Necrosis Factor-alpha

2004
Signal pathways involved in the regulation of prostaglandin E synthase-1 in human gingival fibroblasts.
    Cellular signalling, 2006, Volume: 18, Issue:12

    Topics: Arachidonic Acid; Blotting, Western; Cells, Cultured; Child; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Gingiva; Humans; Imidazoles; Indoles; Interleukin-1beta; Intramolecular Oxidoreductases; Maleimides; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Prostaglandin D2; Prostaglandin-E Synthases; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha

2006
The aromatic volatile organic compounds toluene, benzene and styrene induce COX-2 and prostaglandins in human lung epithelial cells via oxidative stress and p38 MAPK activation.
    Toxicology, 2011, Oct-28, Volume: 289, Issue:1

    Topics: Acetylcysteine; Air Pollutants; Benzene Derivatives; Blotting, Western; Cell Line; Cyclooxygenase 2; Dinoprost; Dinoprostone; Enzyme Activation; Enzyme Induction; Epithelial Cells; Glutathione; Humans; Imidazoles; Lung; MAP Kinase Kinase Kinases; Oxidative Stress; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Pyridines

2011