sb 203580 has been researched along with cycloheximide in 51 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (cycloheximide) | Trials (cycloheximide) | Recent Studies (post-2010) (cycloheximide) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 19,109 | 6 | 861 |
| Protein | Taxonomy | sb 203580 (IC50) | cycloheximide (IC50) |
|---|---|---|---|
| COUP transcription factor 2 isoform a | Homo sapiens (human) | 1.315 | |
| Glucose transporter | Leishmania mexicana | 0.242 | |
| Hexose transporter 1 | Plasmodium falciparum (malaria parasite P. falciparum) | 0.31 | |
| Solute carrier family 2, facilitated glucose transporter member 1 | Homo sapiens (human) | 0.228 | |
| Eukaryotic initiation factor 4A-I | Homo sapiens (human) | 0.139 | |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | 3.6 | |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | 0.036 | |
| Endothelial PAS domain-containing protein 1 | Homo sapiens (human) | 0.036 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (9.80) | 18.2507 |
| 2000's | 38 (74.51) | 29.6817 |
| 2010's | 8 (15.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Debouck, C; Kumar, S; Lee, JC; McDonnell, PC; Orsini, MJ; Young, PR | 1 |
| Fröhli, E; Kessler, R; Klemenz, R; Laursen, NB | 1 |
| Ajisawa, Y; Akahane, M; Miyata, H; Miyazawa, K; Mori, A; Okudaira, H | 1 |
| Bartlett, SR; Mann, GE; Sawdy, R | 1 |
| Behrens, MM; Choi, DW; Gwag, BJ; Koh, JY; Strasser, U | 1 |
| Baudouin-Legros, M; Brouillard, F; Cougnon, M; Edelman, A; Leclerc, T; Tondelier, D | 1 |
| Bigg, HF; Cawston, TE; Clark, IM; McLeod, R; Waters, JG | 1 |
| Hatanaka, H; Ikeuchi, T; Ishikawa, Y | 1 |
| Andersson, K; Sundler, R | 1 |
| Arzt, E; Gloddek, J; Hopfner, U; Korali, Z; Lohrer, P; Nagashima, AC; Pereda, MP; Renner, U; Stalla, GK | 1 |
| Hasegawa, T; Hato, F; Hino, M; Kitagawa, S; Sakamoto, C; Suzuki, K; Tatsumi, N; Zhou, YM | 1 |
| Imaizumi, T; Itaya, H; Koyama, M; Satoh, K; Suzuki, S; Yoshida, H | 1 |
| de Caestecker, MP; Watanabe, H; Yamada, Y | 1 |
| Choi, MR; Suh, HW; Won, JS | 1 |
| Bogoyevitch, MA; Long, CS; Ng, DC | 1 |
| Fong, WF; Lam, W; Leung, CH; Wong, NS; Yang, MS; Zhuang, WJ | 1 |
| Finck, BN; Johnson, RW | 1 |
| Alarcon-Vargas, D; Ronai, Z; Tansey, WP | 1 |
| Gimbrone, MA; Masuda, J; Ochi, H | 1 |
| Ambrosino, C; Black, E; Fritsch, C; Galban, S; Gorospe, M; Mace, G; Nebreda, AR; Vintersten, K | 1 |
| Kim, HA; Kim, YH; Song, YW | 1 |
| Chau, LY; Lee, TS; Tsai, HL | 1 |
| Iwasaka, T; Maeda, A; Nishikawa, M; Toyoda, N; Yasuzawa-Amano, S | 1 |
| Kurland, JF; McDonnell, TJ; Meyn, RE; Munshi, A; Sah, NK; Su, B | 1 |
| Hara, A; Hatakeyama, D; Hirade, K; Hotta, K; Ito, H; Kanamori, Y; Katayama, M; Kato, K; Kozawa, O; Matsuno, H; Mori, H; Niwa, M; Uematsu, T | 1 |
| Choi, SS; Lee, JK; Suh, HW; Won, JS | 1 |
| Hatakeyama, D; Hirade, K; Ito, H; Kato, K; Kozawa, O; Niwa, M; Tokuda, H; Wang, X | 1 |
| Chain, BM; Cho, JY; Katz, DR | 1 |
| Fan, D; Wei, L; Yang, Y; Yao, L; You, H; Yu, Q; Zhang, X; Zhao, Y | 1 |
| Crawley, J; Foxwell, BM; Lali, FV; McCulloch, DA | 1 |
| Hasselgren, PO; Hershko, DD; Luo, GJ; Robb, BW; Wray, CJ | 1 |
| Chang, KC; Kang, YJ; Kim, HJ; Ko, YS; Lee, YS; Park, MK; Pyo, HS; Seo, HG; Yun-Choi, HS | 1 |
| Andreka, P; Bishopric, NH; Evans, WH; Haywood, GA; Martin, PE; Turner, MS; Webster, KA; You, L | 1 |
| Akira, S; Hosoi, T; Matsuda, T; Nomura, Y; Okuma, Y; Suzuki, S; Wada, S | 1 |
| Boutten, A; Cohen, M; Crestani, B; Dehoux, M; Durand, G; Lecon-Malas, V; Marchal-Somme, J; Marchand-Adam, S | 1 |
| Frias, MA; Gerber-Wicht, C; Lang, U; Rebsamen, MC | 1 |
| Chang, JK; Chien, TT; Hsu, YL; Kuo, PL; Tsai, CH | 1 |
| Figulla, HR; Foerster, M; Fritzenwanger, M; Krack, A; Kuethe, F; Meusel, K | 1 |
| Imaizumi, T; Kimura, H; Kobayashi, W; Kubota, K; Kusumi, A; Matsumiya, T; Nakagawa, H; Sakaki, H | 1 |
| Chiasson, S; Girard, D; Pelletier, M; Ratthé, C | 1 |
| Kolling, GL; Lindner, MH; Obrig, TG; Stone, MK | 1 |
| Carraro-Lacroix, LR; Girardi, AC; Malnic, G | 1 |
| Gong, W; Holden, NS; King, EM; Newton, R; Rider, CF | 1 |
| Grden, M; Kocbuch, K; Pawelczyk, T; Sakowicz-Burkiewicz, M; Szutowicz, A | 1 |
| Baird, AW; Collins, D; Hogan, AM; Sheehan, K; Winter, DC; Zierau, O | 1 |
| Boonyarat, C; Noipha, K; Songsiang, U; Thongthoom, T; Yenjai, C | 1 |
| Chaudhuri, G; Cuevas, J; Janzen, C; Reddy, ST; Sen, S | 1 |
| Koshio, O; Mabuchi, A; Nagao, T; Ono, Y; Suzuki, K | 1 |
| Chao, X; Chen, T; Fei, Z; Jiang, X; Li, D; Li, S; Liu, W; Lu, G; Luo, P; Poon, W; Qu, Y; Zhang, L; Zhao, Y | 1 |
| Ayusawa, D; Fujii, M; Kudo, I; Miki, K; Yamakami, Y; Yonekura, R | 1 |
| Chen, CP; Chiu, YH; Guo, YC; Wang, HS | 1 |
51 other study(ies) available for sb 203580 and cycloheximide
| Article | Year |
|---|---|
Activation of the HIV-1 long terminal repeat by cytokines and environmental stress requires an active CSBP/p38 MAP kinase.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cycloheximide; Cytokines; Enzyme Inhibitors; Gene Expression Regulation, Viral; HeLa Cells; HIV Long Terminal Repeat; HIV-1; Humans; Imidazoles; Kinetics; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Protein Synthesis Inhibitors; Pyridines; RNA, Messenger; RNA, Viral; Signal Transduction; Stress, Physiological; Transcription, Genetic; Ultraviolet Rays; Water-Electrolyte Balance | 1996 |
Effects of ras transformation on the induction of the IL-1 receptor related T1 gene in response to mitogens, anisomycin, IL-1 and TNFalpha.
Topics: 3T3 Cells; Animals; Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Cycloheximide; Enzyme Inhibitors; Gene Expression Regulation; Genes, ras; Imidazoles; Interleukin-1; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mitogens; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Pyridines; Receptors, Interleukin-1; Signal Transduction; Stimulation, Chemical; Transcriptional Activation; Transformation, Genetic; Tumor Necrosis Factor-alpha | 1998 |
Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Humans; Imidazoles; Interleukin-1; Interleukin-6; Intracellular Signaling Peptides and Proteins; Kinetics; Mitogen-Activated Protein Kinases; NF-kappa B; Osteoarthritis; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; Recombinant Proteins; Synovial Membrane | 1998 |
Induction of cyclooxygenase-2 expression in human myometrial smooth muscle cells by interleukin-1beta: involvement of p38 mitogen-activated protein kinase.
Topics: Cells, Cultured; Cycloheximide; Cyclooxygenase 2; Dexamethasone; Enzyme Inhibitors; Female; Gene Expression Regulation; Humans; Imidazoles; Interleukin-1; Isoenzymes; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Muscle Contraction; Muscle, Smooth; Myometrium; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Pyridines; RNA, Messenger | 1999 |
Prevention of neuronal apoptosis by phorbol ester-induced activation of protein kinase C: blockade of p38 mitogen-activated protein kinase.
Topics: Amyloid beta-Peptides; Animals; Brain-Derived Neurotrophic Factor; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Culture Media, Serum-Free; Cycloheximide; Enzyme Inhibitors; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Kinetics; Maleimides; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Neurons; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Phorbol Esters; Protein Kinase C; Pyridines; Staurosporine; Tetradecanoylphorbol Acetate | 1999 |
Modulation of CFTR gene expression in HT-29 cells by extracellular hyperosmolarity.
Topics: Blotting, Northern; Cell Survival; Cycloheximide; Cystic Fibrosis Transmembrane Conductance Regulator; Dactinomycin; Diuretics, Osmotic; Enzyme Inhibitors; Extracellular Space; Gene Expression Regulation, Enzymologic; Genes, Reporter; HeLa Cells; HT29 Cells; Humans; Hypertonic Solutions; Imidazoles; Luciferases; Mannitol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Synthesis Inhibitors; Pyridines; Respiratory Mucosa; RNA, Messenger; Sodium Channels; Sodium Chloride; Transcription, Genetic; Water-Electrolyte Balance | 2000 |
Mechanisms of induction of human tissue inhibitor of metalloproteinases-1 (TIMP-1) gene expression by all-trans retinoic acid in combination with basic fibroblast growth factor.
Topics: Cells, Cultured; Cycloheximide; Drug Synergism; Fibroblast Growth Factor 2; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Matrix Metalloproteinase 1; Mitogen-Activated Protein Kinases; Pyridines; Receptors, Retinoic Acid; Retinoid X Receptors; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transcription Factors; Tretinoin | 2000 |
Brain-derived neurotrophic factor accelerates nitric oxide donor-induced apoptosis of cultured cortical neurons.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Butadienes; Carbazoles; Cell Nucleus; Cell Survival; Cells, Cultured; Cerebral Cortex; Cycloheximide; Dactinomycin; DNA Fragmentation; Drug Synergism; Embryo, Mammalian; Enzyme Inhibitors; Female; Imidazoles; Immunoglobulin G; Indole Alkaloids; Kinetics; Male; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Nitric Oxide Donors; Nitriles; Nitroprusside; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Wistar; Receptor, trkB; Signal Transduction | 2000 |
Signalling to translational activation of tumour necrosis factor-alpha expression in human THP-1 cells.
Topics: Anisomycin; Blotting, Northern; Blotting, Western; Butadienes; Calcium; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Ionophores; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Monocytes; Nitriles; p38 Mitogen-Activated Protein Kinases; Protein Biosynthesis; Protein Synthesis Inhibitors; Pyridines; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 2000 |
Lipopolysaccharide directly stimulates the intrapituitary interleukin-6 production by folliculostellate cells via specific receptors and the p38alpha mitogen-activated protein kinase/nuclear factor-kappaB pathway.
Topics: Acute-Phase Proteins; Animals; Antibodies; Carrier Proteins; Cell Line; Cells, Cultured; Cyclic AMP; Cycloheximide; Dexamethasone; Glucocorticoids; Imidazoles; Inositol Phosphates; Interleukin-6; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphatidylinositols; Phosphorylation; Pituitary Gland, Anterior; Pyridines; Signal Transduction | 2000 |
Cleavage of mitogen-activated protein kinases in human neutrophils undergoing apoptosis: role in decreased responsiveness to inflammatory cytokines.
Topics: Adult; Apoptosis; Caspases; Cell Adhesion; Cell Survival; Cells, Cultured; Cycloheximide; Cytokines; DNA Fragmentation; Dose-Response Relationship, Immunologic; Enzyme Inhibitors; Flavonoids; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; HL-60 Cells; Humans; Hydrolysis; Imidazoles; Inflammation; Jurkat Cells; Mitogen-Activated Protein Kinases; Neutrophils; p38 Mitogen-Activated Protein Kinases; Pyridines; Superoxides; Tumor Necrosis Factor-alpha | 2001 |
Expression of vascular endothelial growth factor in human monocyte/macrophages stimulated with lipopolysaccharide.
Topics: Cells, Cultured; Culture Media, Conditioned; Cycloheximide; Dexamethasone; Dose-Response Relationship, Drug; Endothelial Growth Factors; Endothelium, Vascular; Humans; Imidazoles; Kinetics; Lipopolysaccharides; Lymphokines; Macrophages; Mitogen-Activated Protein Kinases; Monocytes; p38 Mitogen-Activated Protein Kinases; Protein Synthesis Inhibitors; Pyridines; RNA, Messenger; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Transcriptional cross-talk between Smad, ERK1/2, and p38 mitogen-activated protein kinase pathways regulates transforming growth factor-beta-induced aggrecan gene expression in chondrogenic ATDC5 cells.
Topics: Aggrecans; Animals; Butadienes; Cell Differentiation; Cell Line; Cell Nucleus; Chondrocytes; Cycloheximide; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Matrix Proteins; Gene Expression Regulation, Enzymologic; Genes, Dominant; Imidazoles; Immunoblotting; Lectins, C-Type; Luciferases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Synthesis Inhibitors; Proteoglycans; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad Proteins; Thiazoles; Time Factors; Trans-Activators; Transcription, Genetic; Transfection; Transforming Growth Factor beta | 2001 |
Stimulation of astrocyte-enriched culture with C2 ceramide increases proenkephalin mRNA: involvement of cAMP-response element binding protein and mitogen activated protein kinases.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Astrocytes; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Enkephalins; Enzyme Inhibitors; Flavonoids; Gene Expression; Imidazoles; Isoquinolines; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Protein Precursors; Protein Synthesis Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sphingosine; Stimulation, Chemical; Sulfonamides; Transcription Factor AP-1 | 2001 |
A role for the extracellular signal-regulated kinase and p38 mitogen-activated protein kinases in interleukin-1 beta-stimulated delayed signal tranducer and activator of transcription 3 activation, atrial natriuretic factor expression, and cardiac myocyte
Topics: Acute-Phase Proteins; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cell Nucleus; Cells, Cultured; Culture Media, Serum-Free; Cycloheximide; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; Growth Inhibitors; Heart; Heart Ventricles; Hypertrophy; Imidazoles; Interleukin-1; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Kinetics; Leukemia Inhibitory Factor; Lymphokines; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Myocardium; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Phosphorylation; Protein Transport; Pyridines; Rats; Rats, Sprague-Dawley; STAT3 Transcription Factor; Trans-Activators | 2001 |
PKCdelta-dependent deubiquitination and stabilization of Gadd45 in A431 cells overexposed to EGF.
Topics: Acetophenones; Benzopyrans; Cell Division; Cycloheximide; DNA Damage; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flavonoids; GADD45 Proteins; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Isoenzymes; Kinetics; Leupeptins; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Proteins; Pyridines; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ubiquitins | 2001 |
Anti-inflammatory agents inhibit the induction of leptin by tumor necrosis factor-alpha.
Topics: Adipose Tissue; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Culture Techniques; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Homeostasis; Imidazoles; Immunologic Factors; Leptin; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mitogen-Activated Protein Kinases; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Prostaglandin D2; Protein Synthesis Inhibitors; Pyridines; RNA, Messenger; Tumor Necrosis Factor-alpha | 2002 |
Regulation of c-myc stability by selective stress conditions and by MEKK1 requires aa 127-189 of c-myc.
Topics: Antineoplastic Agents; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Fibroblasts; Flavonoids; Humans; Imidazoles; MAP Kinase Kinase Kinase 1; Oligopeptides; Peptide Fragments; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-myc; Pyridines; Stress, Physiological; Tumor Necrosis Factor-alpha; Tyrphostins; Ultraviolet Rays | 2002 |
Hyperosmotic stimuli inhibit VCAM-1 expression in cultured endothelial cells via effects on interferon regulatory factor-1 expression and activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Membrane; Cells, Cultured; Culture Media; Cycloheximide; DNA-Binding Proteins; E-Selectin; Endothelium, Vascular; Gene Expression Regulation; GTP-Binding Proteins; Imidazoles; Intercellular Adhesion Molecule-1; Interferon Regulatory Factor-1; Interferon-gamma; Interferon-Stimulated Gene Factor 3; Interleukin-1; Interleukin-13; Interleukin-4; NF-kappa B; Okadaic Acid; Osmosis; Phosphoproteins; Promoter Regions, Genetic; Pyridines; RNA, Messenger; Staurosporine; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2002 |
Negative feedback regulation of MKK6 mRNA stability by p38alpha mitogen-activated protein kinase.
Topics: 3' Untranslated Regions; Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cycloheximide; Enzyme Inhibitors; Feedback, Physiological; Gene Expression Regulation; Imidazoles; MAP Kinase Kinase 3; MAP Kinase Kinase 4; MAP Kinase Kinase 6; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Protein-Tyrosine Kinases; Pyridines; RNA Stability; RNA, Messenger; Up-Regulation | 2003 |
Facilitation of fas mediated apoptosis of human chondrocytes by the proteasome inhibitor and actinomycin D.
Topics: Antibodies, Monoclonal; Apoptosis; Cartilage, Articular; Caspase Inhibitors; Cells, Cultured; Chondrocytes; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; Enzyme Inhibitors; fas Receptor; Humans; Imidazoles; Indoles; Leupeptins; Maleimides; MAP Kinase Signaling System; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Pyridines | 2003 |
Induction of heme oxygenase-1 expression in murine macrophages is essential for the anti-inflammatory effect of low dose 15-deoxy-Delta 12,14-prostaglandin J2.
Topics: Animals; Anti-Inflammatory Agents; Biological Transport; Blotting, Western; Carbon Monoxide; Cell Nucleus; Cycloheximide; Enzyme Induction; Enzyme Inhibitors; Fluorescent Antibody Technique; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; I-kappa B Proteins; Imidazoles; Lipopolysaccharides; Macrophage Activation; Macrophages; Membrane Proteins; Mice; Microscopy, Confocal; Mitogen-Activated Protein Kinases; NF-kappa B; NF-kappa B p50 Subunit; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Organometallic Compounds; p38 Mitogen-Activated Protein Kinases; Prostaglandin D2; Protein Synthesis Inhibitors; Pyridines; Tumor Necrosis Factor-alpha | 2003 |
Type 2 deiodinase expression is stimulated by growth factors in human vascular smooth muscle cells.
Topics: Anthracenes; Cycloheximide; Dactinomycin; Fibroblast Growth Factor 2; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Muscle, Smooth, Vascular; Proto-Oncogene Proteins c-sis; Pyridines; RNA, Messenger | 2003 |
Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase.
Topics: Activating Transcription Factor 2; Anisomycin; Apoptosis; Apoptosis Regulatory Proteins; Curcumin; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genetic Vectors; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase Kinase 2; MAP Kinase Kinase Kinases; Membrane Glycoproteins; Mitogen-Activated Protein Kinases; Peptide Fragments; Prostatic Neoplasms; Protein Biosynthesis; Protein Synthesis Inhibitors; Pyridines; TNF-Related Apoptosis-Inducing Ligand; Transcription Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2003 |
Involvement of p38 mitogen-activated protein kinase in heat shock protein 27 induction in human neutrophils.
Topics: Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Heat-Shock Proteins; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neutrophils; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Synthesis Inhibitors; Pyridines; Pyrrolidines; RNA, Messenger; Thiocarbamates; Time Factors; Tumor Necrosis Factor-alpha | 2003 |
The regulation of inducible nitric oxide synthase gene expression induced by lipopolysaccharide and tumor necrosis factor-alpha in C6 cells: involvement of AP-1 and NFkappaB.
Topics: Animals; Cycloheximide; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Imidazoles; Lipopolysaccharides; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphorylation; Protein Synthesis Inhibitors; Pyridines; Rats; RNA, Messenger; Transcription Factor AP-1; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2003 |
Mechanism of simvastatin on induction of heat shock protein in osteoblasts.
Topics: 3T3 Cells; Animals; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heat-Shock Proteins; Imidazoles; Lovastatin; Mice; Mitogen-Activated Protein Kinases; Osteoblasts; Osteogenesis; p38 Mitogen-Activated Protein Kinases; Pyridines; Reproducibility of Results; RNA, Messenger; Sensitivity and Specificity; Simvastatin | 2003 |
Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation.
Topics: Acetophenones; Adenosine Triphosphate; Benzopyrans; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; CD18 Antigens; Cell Aggregation; Cycloheximide; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Humans; Imidazoles; Indoles; Integrin beta1; Isoenzymes; Maleimides; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Phosphotransferases; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Staurosporine; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; U937 Cells | 2003 |
Distinctive regulation and function of PI 3K/Akt and MAPKs in doxorubicin-induced apoptosis of human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Annexin A5; Apoptosis; Blotting, Western; Carrier Proteins; Caspases; Cell Line, Tumor; Cell Survival; Chromones; Cycloheximide; DNA Fragmentation; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Flavonoids; Flow Cytometry; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Kinetics; Lung Neoplasms; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Signal Transduction | 2004 |
A late, prolonged activation of the phosphatidylinositol 3-kinase pathway is required for T cell proliferation.
Topics: Animals; Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Chromones; Cyclin E; Cycloheximide; Enzyme Activation; Growth Inhibitors; Imidazoles; Interleukin-2; Interleukin-7; Lymphocyte Activation; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pyridines; Retinoblastoma Protein; Signal Transduction; T-Lymphocyte Subsets; Time Factors | 2004 |
Superinduction of IL-6 by cycloheximide is associated with mRNA stabilization and sustained activation of p38 map kinase and NF-kappaB in cultured caco-2 cells.
Topics: Blotting, Western; Caco-2 Cells; Cycloheximide; Dactinomycin; Electrophoretic Mobility Shift Assay; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; I-kappa B Proteins; Imidazoles; Interleukin-1; Interleukin-6; Mitogen-Activated Protein Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
Induction of manganese-superoxide dismutase by YS 51, a synthetic 1-(beta-naphtylmethyl)6,7-dihydroxy- 1,2,3,4-tetrahydroisoquinoline alkaloid: implication for anti-inflammatory actions.
Topics: Animals; Blotting, Northern; Curcumin; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Endothelial Cells; Endothelium, Vascular; Enzyme Induction; Flavonoids; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phorbol Esters; Phosphorylation; Pulmonary Artery; Pyridines; RNA, Messenger; Sheep; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tetrahydroisoquinolines; Tumor Necrosis Factor-alpha | 2004 |
Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels.
Topics: Adenosine Triphosphate; Alkaloids; Aminoimidazole Carboxamide; Animals; Antimycin A; Benzophenanthridines; Brefeldin A; Carbazoles; Cell Hypoxia; Cells, Cultured; Connexin 43; Cycloheximide; Deoxyglucose; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Myocardial Contraction; Myocytes, Cardiac; Okadaic Acid; Ouabain; Phenanthridines; Phosphorylation; Potassium Cyanide; Protein Processing, Post-Translational; Pyridines; Pyrroles; Rats; Recombinant Fusion Proteins; Ribonucleotides; Staurosporine; Tacrolimus; Tetradecanoylphorbol Acetate | 2004 |
Bacterial endotoxin induces IL-20 expression in the glial cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; Animals, Newborn; Antigens, Differentiation; Blotting, Western; Brain; Cells, Cultured; Cycloheximide; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gene Expression Regulation; Glucocorticoids; Imidazoles; Interleukins; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88; Neuroglia; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Protein Synthesis Inhibitors; Puromycin; Pyridines; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
HGF synthesis in human lung fibroblasts is regulated by oncostatin M.
Topics: Cell Line; Cells, Cultured; Cycloheximide; Cytokines; Fibroblasts; Hepatocyte Growth Factor; Humans; Imidazoles; Lung; Oncostatin M; Protein Synthesis Inhibitors; Pyridines; RNA, Messenger; Wound Healing | 2006 |
Prostaglandin E2 activates Stat3 in neonatal rat ventricular cardiomyocytes: A role in cardiac hypertrophy.
Topics: Animals; Animals, Newborn; Blotting, Western; Butadienes; Cardiomegaly; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gene Silencing; Genistein; Imidazoles; Janus Kinases; Myocytes, Cardiac; Nitriles; Phosphorylation; Protein Synthesis Inhibitors; Pyridines; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; RNA Interference; Signal Transduction; STAT3 Transcription Factor; Stress, Mechanical | 2007 |
Myricetin induces human osteoblast differentiation through bone morphogenetic protein-2/p38 mitogen-activated protein kinase pathway.
Topics: Alkaline Phosphatase; Autoantigens; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Carrier Proteins; Cell Differentiation; Cell Line; Cell Line, Tumor; Collagen Type I; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flavonoids; Humans; Imidazoles; Osteoblasts; Osteocalcin; p38 Mitogen-Activated Protein Kinases; Protein Synthesis Inhibitors; Pyridines; Ribonucleoproteins, Small Nuclear; Signal Transduction; Smad5 Protein; Smad8 Protein; snRNP Core Proteins; Time Factors; Transforming Growth Factor beta | 2007 |
Cardiotrophin-1 induces interleukin-6 synthesis in human umbilical vein endothelial cells.
Topics: Antibodies, Monoclonal; Cells, Cultured; Cycloheximide; Cytokines; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gene Expression; Humans; Imidazoles; Interleukin-6; Janus Kinase 2; Kinetics; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sesquiterpenes; STAT3 Transcription Factor; Stilbenes; Tyrphostins; Umbilical Cord | 2006 |
Expression of vascular endothelial growth factor by photodynamic therapy with mono-L-aspartyl chlorin e6 (NPe6) in oral squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cycloheximide; Deferoxamine; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Free Radical Scavengers; Genes, fos; Genes, jun; Humans; Imidazoles; Mouth Neoplasms; p38 Mitogen-Activated Protein Kinases; Photochemotherapy; Photosensitizing Agents; Porphyrins; Protein Synthesis Inhibitors; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Siderophores; Vascular Endothelial Growth Factor A | 2007 |
Molecular mechanisms involved in interleukin-4-induced human neutrophils: expression and regulation of suppressor of cytokine signaling.
Topics: Apoptosis; Cycloheximide; Dose-Response Relationship, Drug; Flavonoids; Gene Expression Profiling; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; Interleukin-4; Leupeptins; Neutrophils; Pyridines; Receptors, Interleukin-4, Type I; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship; Suppressor of Cytokine Signaling Proteins; Tyrphostins | 2007 |
p38 mitogen-activated protein kinase mediates lipopolysaccharide and tumor necrosis factor alpha induction of shiga toxin 2 sensitivity in human umbilical vein endothelial cells.
Topics: Cell Survival; Cells, Cultured; Cycloheximide; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Escherichia coli O157; Gene Silencing; Humans; Imidazoles; Lipopolysaccharides; p38 Mitogen-Activated Protein Kinases; Pyridines; Shiga Toxin 2; Time Factors; Trihexosylceramides; Tumor Necrosis Factor-alpha | 2008 |
Long-term regulation of vacuolar H(+)-ATPase by angiotensin II in proximal tubule cells.
Topics: Ammonium Chloride; Androstadienes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Buffers; Cell Line, Transformed; Cell Membrane; Cycloheximide; Dactinomycin; Epithelial Cells; Gene Expression; Genistein; Hydrogen-Ion Concentration; Imidazoles; Kidney Tubules, Proximal; Losartan; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein Subunits; Protein Transport; Protein-Tyrosine Kinases; Pyridines; Rats; Time Factors; Up-Regulation; Vacuolar Proton-Translocating ATPases; Wortmannin | 2009 |
Inhibition of NF-kappaB-dependent transcription by MKP-1: transcriptional repression by glucocorticoids occurring via p38 MAPK.
Topics: Blotting, Western; Cell Line; Cell Line, Tumor; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Dual Specificity Phosphatase 1; Enzyme Inhibitors; Gene Expression Regulation; Glucocorticoids; Humans; Imidazoles; Interleukin-8; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2009 |
Regulation of adenosine receptors expression in rat B lymphocytes by insulin.
Topics: Animals; B-Lymphocytes; Cells, Cultured; Cycloheximide; Extracellular Signal-Regulated MAP Kinases; Imidazoles; Insulin; Mitogen-Activated Protein Kinase Kinases; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-raf; Pyridines; ras Proteins; Rats; Receptors, Purinergic P1; Signal Transduction | 2010 |
Rapid effects of phytoestrogens on human colonic smooth muscle are mediated by oestrogen receptor beta.
Topics: Butadienes; Colon; Cycloheximide; Estradiol; Estrogen Receptor beta; Fulvestrant; Humans; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitriles; Phytoestrogens; Pyridines; Reproducibility of Results; Tissue Survival | 2010 |
Carbazoles and coumarins from Clausena harmandiana stimulate glucose uptake in L6 myotubes.
Topics: Carbazoles; Cell Survival; Cells, Cultured; Clausena; Coumarins; Cycloheximide; Cytochalasin B; Deoxyglucose; Humans; Imidazoles; Muscle Fibers, Skeletal; p38 Mitogen-Activated Protein Kinases; Plant Extracts; Plant Roots; Pyridines | 2010 |
Protein phosphatase 2A promotes endothelial survival via stabilization of translational inhibitor 4E-BP1 following exposure to tumor necrosis factor-α.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Cell Cycle Proteins; Cell Survival; Cells, Cultured; Cycloheximide; Endothelium, Vascular; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Protein Phosphatase 2; Pyridines; RNA, Small Interfering; Tumor Necrosis Factor-alpha | 2011 |
Apoptotic signaling in endothelial cells with neutrophil activation.
Topics: Activating Transcription Factor 2; Apoptosis; Caspases; Cell Degranulation; Cells, Cultured; Coculture Techniques; Cycloheximide; Enzyme Activation; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Imidazoles; Inflammation Mediators; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Neutrophil Activation; Neutrophils; p38 Mitogen-Activated Protein Kinases; Paracrine Communication; Peroxidase; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha | 2012 |
Protective effect of Homer 1a on tumor necrosis factor-α with cycloheximide-induced apoptosis is mediated by mitogen-activated protein kinase pathways.
Topics: Adrenal Gland Neoplasms; Animals; Anthracenes; Apoptosis; Brain-Derived Neurotrophic Factor; Carrier Proteins; Cell Line, Tumor; Cell Survival; Cycloheximide; Extracellular Signal-Regulated MAP Kinases; Flavonoids; HEK293 Cells; Homer Scaffolding Proteins; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Pheochromocytoma; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Pyridines; Rats; RNA Interference; RNA, Small Interfering; Tumor Necrosis Factor-alpha | 2012 |
Molecular basis for premature senescence induced by surfactants in normal human cells.
Topics: beta-Galactosidase; Binding, Competitive; Cell Line; Cell Membrane; Cellular Senescence; Cycloheximide; Fibroblasts; Gene Expression Regulation; Genes, Reporter; HeLa Cells; Humans; Imidazoles; Keratinocytes; Octoxynol; Oleic Acid; p38 Mitogen-Activated Protein Kinases; Polyethylene Glycols; Protein Synthesis Inhibitors; Pyridines; Signal Transduction; Surface-Active Agents | 2014 |
Interleukin-1β induces CXCR3-mediated chemotaxis to promote umbilical cord mesenchymal stem cell transendothelial migration.
Topics: Acetamides; Chemokine CXCL9; Chemotaxis; Coculture Techniques; Cycloheximide; Diffusion Chambers, Culture; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Interleukin-1beta; Mesenchymal Stem Cells; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrimidinones; Receptors, CXCR3; RNA, Messenger; Umbilical Cord | 2018 |