sb 203580 has been researched along with cyclic gmp in 14 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (cyclic gmp) | Trials (cyclic gmp) | Recent Studies (post-2010) (cyclic gmp) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 22,346 | 333 | 4,062 |
| Protein | Taxonomy | sb 203580 (IC50) | cyclic gmp (IC50) |
|---|---|---|---|
| Phosphodiesterase | Bos taurus (cattle) | 0.1 | |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Homo sapiens (human) | 2.4 | |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Homo sapiens (human) | 2.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 9 (64.29) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Begum, N; Duddy, N; McCarthy, M; Ragolia, L; Rienzie, J | 1 |
| Cai, L; Ingram, AJ; James, L; Ly, H; Scholey, JW; Thai, K | 1 |
| Andreka, P; Bishopric, NH; Dougherty, C; Slepak, TI; Webster, KA; Zang, J | 1 |
| Bonavita, F; Facchini, A; Flamigni, F; Stanic, I; Stefanelli, C; Tantini, B | 1 |
| Cao, L; Chen, S; Gardner, DG; Humphreys, M; Intengan, HD | 1 |
| Brørs, O; Jensen, J; Melien, Ø; Sharikabad, MN; Østbye, KM | 1 |
| Chen, S; Gardner, DG; McCormick, JA; Pearce, D; Prabaker, K; Wang, J | 1 |
| Chen, YM; Chiang, WC; Hsieh, BS; Lin, SL; Teng, CM; Tsai, TJ | 1 |
| Ma, L; Wang, HY | 1 |
| Aggeli, IK; Beis, I; Gaitanaki, C; Iliodromitis, EK; Kremastinos, DT; Tsiafoutis, I; Zoga, A | 1 |
| Makris, AC; Makropoulou, M; Papapetropoulos, A; Papapetropoulos, N; Pyriochou, A; Roussos, C; Sotzios, Y; Vassilakopoulos, T; Zacharatos, P; Zhou, Z | 1 |
| Choi, I; Jeong, M; Kang, YH; Kim, MJ; Kim, MS; Kim, TD; Lee, SH; Myung, PK; Piao, ZH; Suh, HW; Yoon, SR; Yun, S | 1 |
| Blakely, RD; Carneiro, AM; Chang, JC; Piston, DW; Rosenthal, SJ; Tomlinson, ID; Ustione, A; Warnement, MR | 1 |
| Beeram, MR; Kohl-Thomas, BM; Kuehl, TJ; Lin, S; Nguyen, T; Pantho, AF; Uddin, MN; Zawieja, DC | 1 |
14 other study(ies) available for sb 203580 and cyclic gmp
| Article | Year |
|---|---|
Regulation of mitogen-activated protein kinase phosphatase-1 induction by insulin in vascular smooth muscle cells. Evaluation of the role of the nitric oxide signaling pathway and potential defects in hypertension.
Topics: Androstadienes; Animals; Cell Cycle Proteins; Cells, Cultured; Cyclic GMP; Dual Specificity Phosphatase 1; Enzyme Inhibitors; Flavonoids; Imidazoles; Immediate-Early Proteins; Insulin; Male; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Signal Transduction; Wortmannin | 1998 |
Nitric oxide modulates mechanical strain-induced activation of p38 MAPK in mesangial cells.
Topics: Animals; Biological Transport; Cells, Cultured; Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Fluorescent Antibody Technique; Glomerular Mesangium; Imidazoles; Mitogen-Activated Protein Kinases; Molsidomine; Nitric Oxide; Nitric Oxide Donors; p38 Mitogen-Activated Protein Kinases; Penicillamine; Pyridines; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Stress, Mechanical | 2000 |
Cytoprotection by Jun kinase during nitric oxide-induced cardiac myocyte apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspase Inhibitors; Caspases; Cells, Cultured; Cyclic GMP; Cysteine Proteinase Inhibitors; DNA Fragmentation; DNA, Recombinant; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glutathione; Imidazoles; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Myocardium; Nitric Oxide; Nitroso Compounds; Plasmids; Protein Serine-Threonine Kinases; Pyridines; S-Nitrosoglutathione; Transfection | 2001 |
Control of survival of proliferating L1210 cells by soluble guanylate cyclase and p44/42 mitogen-activated protein kinase modulators.
Topics: Animals; Apoptosis; Caspases; Cell Division; Cell Survival; Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Guanylate Cyclase; Imidazoles; Leukemia L1210; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxadiazoles; Oxidation-Reduction; Proto-Oncogene Proteins c-bcl-2; Pyridines; Quinoxalines; Signal Transduction; Tumor Cells, Cultured | 2001 |
Osmoregulation of endothelial nitric-oxide synthase gene expression in inner medullary collecting duct cells. Role in activation of the type A natriuretic peptide receptor.
Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Green Fluorescent Proteins; Guanylate Cyclase; Imidazoles; Kidney Medulla; Kidney Tubules, Collecting; Luciferases; Luminescent Proteins; Mitogen-Activated Protein Kinases; Models, Biological; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Osmosis; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor; RNA; RNA, Messenger; Signal Transduction; Sodium; Sodium Chloride; Time Factors; Transfection | 2002 |
Evidence that nitroprusside stimulates glucose uptake in isolated rat cardiomyocytes via mitogen-activated protein kinase.
Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ferricyanides; Flavonoids; Glucose; Imidazoles; Male; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Pyridines; Quinoxalines; Rats; Rats, Wistar; Spermine | 2003 |
Sgk1 mediates osmotic induction of NPR-A gene in rat inner medullary collecting duct cells.
Topics: Animals; Cells, Cultured; Cyclic GMP; Female; Gene Expression Regulation; Genes, Reporter; Guanylate Cyclase; Imidazoles; Immediate-Early Proteins; Kidney Tubules, Collecting; Luciferases; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Natriuresis; Nuclear Proteins; Osmolar Concentration; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor; Recombinant Fusion Proteins; RNA, Messenger; Saline Solution, Hypertonic; Transfection | 2004 |
YC-1-inhibited proliferation of rat mesangial cells through suppression of cyclin D1-independent of cGMP pathway and partially reversed by p38 MAPK inhibitor.
Topics: Animals; Blotting, Northern; Blotting, Western; Bromodeoxyuridine; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Enzyme Inhibitors; G1 Phase; Gene Expression; Glomerular Mesangium; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Guanylate Cyclase; Imidazoles; Indazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Rats; RNA, Messenger; Signal Transduction; Solubility; Tumor Suppressor Proteins | 2005 |
Mitogen-activated protein kinase p38 regulates the Wnt/cyclic GMP/Ca2+ non-canonical pathway.
Topics: Adaptor Proteins, Signal Transducing; Animals; Calcium; Calcium Signaling; Cell Line, Tumor; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 6; Dishevelled Proteins; Enzyme Activation; Enzyme Inhibitors; Frizzled Receptors; Imidazoles; Intracellular Signaling Peptides and Proteins; Mice; NFATC Transcription Factors; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphoproteins; Phosphoric Diester Hydrolases; Pyridines; Receptors, G-Protein-Coupled; RGS Proteins; RNA-Binding Proteins; Wnt Proteins; Wnt-5a Protein | 2007 |
p38-MAPK is involved in restoration of the lost protection of preconditioning by nicorandil in vivo.
Topics: Animals; Anti-Arrhythmia Agents; Cyclic GMP; Imidazoles; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Nicorandil; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Potassium Channels; Protein Kinase C; Pyridines; Rabbits; Signal Transduction | 2008 |
Nitric oxide stimulates interleukin-6 production in skeletal myotubes.
Topics: Animals; Cell Line; Cyclic GMP; Flavonoids; Imidazoles; Immunization; Interleukin-6; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 3; Muscle Fibers, Skeletal; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; p38 Mitogen-Activated Protein Kinases; Pyrazoles; Pyridines; Quinoxalines; Up-Regulation | 2010 |
YC-1 enhances natural killer cell differentiation from hematopoietic stem cells.
Topics: Blotting, Western; Cell Differentiation; Cell Line, Tumor; Cyclic GMP; Enzyme Activators; Enzyme Inhibitors; Fetal Blood; Flow Cytometry; Hematopoietic Stem Cells; Humans; Imidazoles; Indazoles; Killer Cells, Natural; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptors, Interleukin-15; Signal Transduction; STAT5 Transcription Factor | 2010 |
Single molecule analysis of serotonin transporter regulation using antagonist-conjugated quantum dots reveals restricted, p38 MAPK-dependent mobilization underlying uptake activation.
Topics: Actins; Animals; beta-Cyclodextrins; Cell Line, Transformed; Cholera Toxin; Cholesterol; Cyclic GMP; Cytochalasin D; Enzyme Inhibitors; Gangliosidosis, GM1; Imidazoles; Ligands; Membrane Microdomains; Microscopy, Confocal; Neurons; Normal Distribution; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Protein Transport; Pyridines; Quantum Dots; Rats; Serotonin; Serotonin Plasma Membrane Transport Proteins; Thionucleotides | 2012 |
Hyperglycemia down-regulates cGMP-dependent protein kinase I expression in first trimester cytotrophoblast cells.
Topics: Cell Line; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Down-Regulation; Female; Glucose; Guanylate Cyclase; Humans; Hyperglycemia; Imidazoles; Pregnancy; Pregnancy Trimester, First; Pyridines; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Signal Transduction; Soluble Guanylyl Cyclase; Thiazolidinediones; Trophoblasts | 2015 |