sb 203580 has been researched along with curcumin in 33 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (curcumin) | Trials (curcumin) | Recent Studies (post-2010) (curcumin) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 16,336 | 593 | 12,705 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 18 (54.55) | 29.6817 |
| 2010's | 13 (39.39) | 24.3611 |
| 2020's | 2 (6.06) | 2.80 |
| Authors | Studies |
|---|---|
| Chokchaisiri, R; Chuprajob, T; Lin, Y; Lu, X; Shen, X; Sornkaew, N; Suksamrarn, A; Wang, F; Wang, P; Wongkrajang, K; Yang, L; Yang, N; Zhang, G; Zhou, Z | 1 |
| Ishikawa, Y; Kitamura, M | 1 |
| Cordis, GA; Das, DK; Maulik, N; Sato, M | 1 |
| Kitamura, M; Konta, T; Lucio-Cazana, J; Moreno-Manzano, V; Nakayama, K | 1 |
| Grant, S; Vrana, JA | 1 |
| Klein, JP; Neff, L; Schöller-Guinard, M; Sibilia, J; Wachsmann, D; Zeisel, M | 1 |
| Hsu, HY; Wen, MH | 1 |
| Li, WQ; Liacini, A; Sylvester, J; Zafarullah, M | 1 |
| Fabra, A; Guerrero, J; Martínez, J; Quintanilla, M; Santibáñez, JF | 1 |
| Langille, BL; Liu, M; Lye, SJ; Oldenhof, AD; Shynlova, OP | 1 |
| Batuman, V; Sengul, S; Zwizinski, C | 1 |
| Kurland, JF; McDonnell, TJ; Meyn, RE; Munshi, A; Sah, NK; Su, B | 1 |
| Demedts, MG; Dupont, LJ; Vanaudenaerde, BM; Verleden, GM; Wuyts, WA | 1 |
| Baker, JE; Eis, AL; Fitzpatrick, CM; Jaquiss, RD; Komorowski, RA; Litwin, SB; Mussatto, K; Ogawa, H; Pritchard, KA; Rafiee, P; Shi, Y; Tweddell, JS | 1 |
| Chang, KC; Kang, YJ; Kim, HJ; Ko, YS; Lee, YS; Park, MK; Pyo, HS; Seo, HG; Yun-Choi, HS | 1 |
| Campbell, FC; Collett, GP | 1 |
| Ip, WK; Lam, CW; Li, ML; Tian, YP; Wang, CB; Wong, CK | 1 |
| Binion, DG; Floer, M; Manley, S; Nelson, VM; Rafiee, P; Shaker, R; Wellner, M | 1 |
| Chen, HM; Cheng, SJ; Chiang, CP; Deng, YT; Kuo, MY | 1 |
| Rengifo-Cam, W; Sarkar, S; Singh, AP; Singh, P; Umar, S; Wood, TG | 1 |
| Dong, S; Wang, J | 1 |
| Graham, K; Lanza-Jacoby, S; Yan, G | 1 |
| Callaway, Z; Chung, HT; Joe, Y; Lee, SJ; Shin, DY; Woo, JM; Yim, JH; Zheng, M | 1 |
| Chang, CH; Chen, HT; Tang, CH; Tsou, HK; Yang, WY | 1 |
| Ahmad, R; Chaudry, A; El Mabrouk, M; Sylvester, J; Zafarullah, M | 1 |
| Chang, YC; Huang, FM; Kuan, YH; Lee, SS; Tsai, CH | 1 |
| Chen, XG; Jin, XB; Li, L; Liu, MY; Mao, JW; Meng, MJ; Pu, QH; Wang, WZ; Zhu, JY | 1 |
| Chang, HH; Chang, JZ; Deng, YT; Kuo, MY; Liu, CM; Yang, WH | 1 |
| Han, M; Liu, XC; Xia, JM; Zhang, J; Zhou, WX | 1 |
| Dong, HJ; Peng, DW; Shang, CZ; Wang, P; Xu, J; Xu, PX; Zhan, L | 1 |
| Rui, X; Yan, X; Zhang, K | 1 |
| Chen, Y; Geng, S; Jiang, Y; Li, X; Li, Y; Meng, Y; Wang, S; Wang, X; Wu, J; Xie, C; Yang, X; Zhong, C; Zhu, J; Zhu, W | 1 |
| He, H; Jia, Y; Peng, L; Qiao, K; Wang, C; Xu, Z; Yang, W; Zhang, C; Zhang, Z | 1 |
33 other study(ies) available for sb 203580 and curcumin
| Article | Year |
|---|---|
Discovery of diarylheptanoids that activate α7 nAchR-JAK2-STAT3 signaling in macrophages with anti-inflammatory activity in vitro and in vivo.
Topics: Animals; Anti-Inflammatory Agents; Diarylheptanoids; Janus Kinase 2; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Sepsis; STAT3 Transcription Factor | 2022 |
Anti-apoptotic effect of quercetin: intervention in the JNK- and ERK-mediated apoptotic pathways.
Topics: Animals; Apoptosis; Cells, Cultured; Curcumin; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Glomerular Mesangium; Hydrogen Peroxide; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Mutagenesis; Oxidants; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyridines; Quercetin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription Factor AP-1; Transfection | 2000 |
SAPKs regulation of ischemic preconditioning.
Topics: Animals; Anisomycin; Curcumin; Enzyme Inhibitors; Heart; Imidazoles; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-jun; Pyridines; Rats; Rats, Sprague-Dawley | 2000 |
Enhancement of TNF-alpha-induced apoptosis by immobilized arginine-glycine-aspartate: involvement of a tyrosine kinase-dependent, MAP kinase-independent mechanism.
Topics: Animals; Apoptosis; Benzoquinones; Cells, Cultured; Curcumin; Enzyme Inhibitors; Flavonoids; Genes, Dominant; Genistein; Glomerular Mesangium; Hydrogen Peroxide; Imidazoles; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; MAP Kinase Signaling System; Microscopy, Phase-Contrast; Mitogen-Activated Protein Kinases; Mutation; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Protein-Tyrosine Kinases; Pyridines; Quinones; Rats; Rifabutin; Time Factors; Transcription Factor AP-1; Transfection; Tumor Necrosis Factor-alpha | 2000 |
Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.
Topics: Acetylcysteine; Amanitins; Aminoacetonitrile; Apoptosis; Benzoquinones; Bryostatins; Butadienes; Curcumin; Cysteine Endopeptidases; Dactinomycin; Diterpenes; Drug Synergism; Enzyme Activation; Flavonoids; Humans; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; Lactones; Macrolides; Maleimides; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Neoplasm Proteins; Nitriles; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-raf; Pyridines; Quinones; Terpenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Type C Phospholipases; U937 Cells; Ubiquitins | 2001 |
NF-kappaB and the MAP kinases/AP-1 pathways are both involved in interleukin-6 and interleukin-8 expression in fibroblast-like synoviocytes stimulated by protein I/II, a modulin from oral streptococci.
Topics: Anti-Bacterial Agents; Apigenin; Arthritis, Rheumatoid; Bacterial Proteins; Cells, Cultured; Curcumin; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Interleukin-6; Interleukin-8; MAP Kinase Signaling System; Membrane Glycoproteins; NF-kappa B; Pyridines; Signal Transduction; Streptococcus; Sulfasalazine; Synovial Membrane | 2001 |
Lipopolysaccharide-mediated reactive oxygen species and signal transduction in the regulation of interleukin-1 gene expression.
Topics: Animals; Carrier Proteins; Cell Line; Chromones; Curcumin; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flavonoids; Gene Expression Regulation; Genes, Dominant; Imidazoles; Interleukin-1; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Biological; Morpholines; Naphthalenes; Oxygen; p38 Mitogen-Activated Protein Kinases; Protein Binding; Pyridines; rac1 GTP-Binding Protein; Reactive Oxygen Species; Signal Transduction; Time Factors; Transfection | 2002 |
Inhibition of interleukin-1-stimulated MAP kinases, activating protein-1 (AP-1) and nuclear factor kappa B (NF-kappa B) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes.
Topics: Animals; Cartilage, Articular; Cattle; Cells, Cultured; Chondrocytes; Collagenases; Curcumin; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Femur Head; Gene Expression Regulation, Enzymologic; Humans; Imidazoles; Interleukin-1; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Osteoarthritis, Hip; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrrolidines; Thiocarbamates; Time Factors; Transcription Factor AP-1 | 2002 |
Transforming growth factor-beta1 modulates matrix metalloproteinase-9 production through the Ras/MAPK signaling pathway in transformed keratinocytes.
Topics: Animals; Cell Line, Transformed; Cell Transformation, Neoplastic; Curcumin; Dipeptides; Enzyme Inhibitors; Flavonoids; Genes, Reporter; Humans; Imidazoles; Keratinocytes; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Oligodeoxyribonucleotides, Antisense; Promoter Regions, Genetic; Pyridines; ras Proteins; Recombinant Proteins; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured | 2002 |
Mitogen-activated protein kinases mediate stretch-induced c-fos mRNA expression in myometrial smooth muscle cells.
Topics: Animals; Butadienes; Cells, Cultured; Curcumin; Enzyme Inhibitors; Female; Flavonoids; Gene Expression; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth; Myometrium; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pregnancy; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Uterine Contraction | 2002 |
Role of MAPK pathways in light chain-induced cytokine production in human proximal tubule cells.
Topics: Blotting, Western; Butadienes; Chemokine CCL2; Curcumin; Cytokines; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Imidazoles; Immunoblotting; Interleukin-6; Kidney Tubules, Proximal; Mitogen-Activated Protein Kinases; Myeloma Proteins; NF-kappa B; Nitriles; Phosphorylation; Pyridines; Signal Transduction | 2003 |
Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase.
Topics: Activating Transcription Factor 2; Anisomycin; Apoptosis; Apoptosis Regulatory Proteins; Curcumin; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genetic Vectors; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase Kinase 2; MAP Kinase Kinase Kinases; Membrane Glycoproteins; Mitogen-Activated Protein Kinases; Peptide Fragments; Prostatic Neoplasms; Protein Biosynthesis; Protein Synthesis Inhibitors; Pyridines; TNF-Related Apoptosis-Inducing Ligand; Transcription Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2003 |
Involvement of p38 MAPK, JNK, p42/p44 ERK and NF-kappaB in IL-1beta-induced chemokine release in human airway smooth muscle cells.
Topics: Asthma; Blotting, Northern; Butadienes; Cells, Cultured; Chemokine CCL11; Chemokine CCL2; Chemokine CCL7; Chemokines; Chemokines, CC; Curcumin; Cytokines; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Immunoblotting; Interleukin-1; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Monocyte Chemoattractant Proteins; Muscle, Smooth; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Pyrrolidines; Stimulation, Chemical; Thiocarbamates | 2003 |
Cellular redistribution of inducible Hsp70 protein in the human and rabbit heart in response to the stress of chronic hypoxia: role of protein kinases,.
Topics: Alkaloids; Animals; Benzophenanthridines; Blotting, Western; Curcumin; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Female; Heart; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Hypoxia; Imidazoles; Immunohistochemistry; Infant; Infant, Newborn; Ischemia; Male; MAP Kinase Signaling System; Membrane Proteins; Myocardium; Phenanthridines; Protein Kinase C; Pyridines; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors | 2003 |
Induction of manganese-superoxide dismutase by YS 51, a synthetic 1-(beta-naphtylmethyl)6,7-dihydroxy- 1,2,3,4-tetrahydroisoquinoline alkaloid: implication for anti-inflammatory actions.
Topics: Animals; Blotting, Northern; Curcumin; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Endothelial Cells; Endothelium, Vascular; Enzyme Induction; Flavonoids; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phorbol Esters; Phosphorylation; Pulmonary Artery; Pyridines; RNA, Messenger; Sheep; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tetrahydroisoquinolines; Tumor Necrosis Factor-alpha | 2004 |
Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells.
Topics: Anthracenes; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Curcumin; Enzyme Inhibitors; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; NF-kappa B; Pyridines; Signal Transduction | 2004 |
House dust mite allergen Der p 1 elevates the release of inflammatory cytokines and expression of adhesion molecules in co-culture of human eosinophils and bronchial epithelial cells.
Topics: Antigens, Dermatophagoides; Arthropod Proteins; Asthma; Bronchi; Cell Adhesion Molecules; Coculture Techniques; Curcumin; Cysteine Endopeptidases; Cytokines; Dermatophagoides pteronyssinus; Enzyme Activation; Eosinophils; Epithelial Cells; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyroglyphidae; Sulfones; Th2 Cells; Transcription Factor AP-1 | 2006 |
Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-kappaB.
Topics: Anthracenes; Anti-Inflammatory Agents; Benzophenanthridines; Cell Line; Curcumin; Enzyme Activation; Epithelial Cells; Esophagus; Flavonoids; Humans; Hydrogen-Ion Concentration; Imidazoles; Interleukin-6; Interleukin-8; Mitogen-Activated Protein Kinases; Mucous Membrane; NF-kappa B; Peptides; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Telomerase; Time Factors; Transcription, Genetic; Up-Regulation | 2009 |
Arecoline-stimulated connective tissue growth factor production in human buccal mucosal fibroblasts: Modulation by curcumin.
Topics: Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Arecoline; Cheek; Cholinergic Agonists; Connective Tissue Growth Factor; Curcumin; Endothelial Cells; Epithelial Cells; Fibroblasts; Flavonoids; Humans; Imidazoles; Mouth Mucosa; Nitriles; Oral Submucous Fibrosis; Pyridines; Sulfones | 2009 |
Insulin-like growth factors are more effective than progastrin in reversing proapoptotic effects of curcumin: critical role of p38MAPK.
Topics: Animals; Antibodies; Apoptosis; Autocrine Communication; Caco-2 Cells; Camptothecin; Caspase 3; Caspase 9; Cell Line; Cell Proliferation; CSK Tyrosine-Protein Kinase; Curcumin; Epithelial Cells; Gastrins; Humans; I-kappa B Kinase; Ileum; Imidazoles; Insulin-Like Growth Factor II; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Protein Precursors; Protein-Tyrosine Kinases; Pyridines; Rats; Somatomedins; src-Family Kinases; Transcription Factor RelA; Transfection | 2010 |
ICAM-1 and IL-8 are expressed by DEHP and suppressed by curcumin through ERK and p38 MAPK in human umbilical vein endothelial cells.
Topics: Cell Line; Cell Survival; Curcumin; Diethylhexyl Phthalate; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-8; MAP Kinase Signaling System; Medicine, Chinese Traditional; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; RNA, Messenger | 2012 |
Curcumin enhances the anticancer effects of trichostatin a in breast cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Curcumin; Cyclin D1; Enzyme Inhibitors; Female; Humans; Hydroxamic Acids; Imidazoles; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines | 2013 |
Curcumin protects retinal pigment epithelial cells against oxidative stress via induction of heme oxygenase-1 expression and reduction of reactive oxygen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Line; Cell Survival; Curcumin; Cytoprotection; Epithelial Cells; Gene Expression; Heme Oxygenase-1; Humans; Hydrogen Peroxide; Imidazoles; Oxidative Stress; Pyridines; Reactive Oxygen Species; Retinal Pigment Epithelium; RNA, Small Interfering; Up-Regulation | 2012 |
Apoptosis signal-regulating kinase 1 is mediated in TNF-α-induced CCL2 expression in human synovial fibroblasts.
Topics: Anthracenes; Antibodies; Bursa, Synovial; Chemokine CCL2; Curcumin; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Genes, Reporter; Humans; Imidazoles; Luciferases; MAP Kinase Kinase 4; MAP Kinase Kinase Kinase 5; Osteoarthritis; p38 Mitogen-Activated Protein Kinases; Primary Cell Culture; Pyridines; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Thioredoxins; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2012 |
Interleukin-1 induction of aggrecanase gene expression in human articular chondrocytes is mediated by mitogen-activated protein kinases.
Topics: Anthracenes; Butadienes; Cartilage, Articular; Cells, Cultured; Chondrocytes; Curcumin; Endopeptidases; Gene Expression Regulation; Humans; Imidazoles; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Lipoxygenases; Masoprocol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Pyrrolidines; RNA, Messenger; Thiocarbamates; Transcription Factor AP-1 | 2012 |
The upregulation of transglutaminase-2 by cyclosporin a in human gingival fibroblasts is augmented by oxidative stress.
Topics: Acetylcysteine; Adult; Antioxidants; Catechin; Cell Culture Techniques; Cells, Cultured; Chromones; Curcumin; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Flavonoids; Free Radical Scavengers; Gingiva; GTP-Binding Proteins; Humans; Imidazoles; Immunosuppressive Agents; Male; Morpholines; Oxidative Stress; Phosphoinositide-3 Kinase Inhibitors; Protease Inhibitors; Protein Glutamine gamma Glutamyltransferase 2; Pyridines; Reactive Oxygen Species; Transglutaminases; Up-Regulation | 2013 |
Curcumin induces FasL-related apoptosis through p38 activation in human hepatocellular carcinoma Huh7 cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase Inhibitors; Cell Line, Tumor; Curcumin; Fas Ligand Protein; fas Receptor; Humans; Imidazoles; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; Up-Regulation | 2013 |
Curcumin inhibits TGFβ1-induced CCN2 via Src, JNK, and Smad3 in gingiva.
Topics: Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Cell Culture Techniques; Cell Movement; Cells, Cultured; Connective Tissue Growth Factor; Curcumin; Enzyme Inhibitors; Fibroblasts; Flavonoids; Gingiva; Gingival Overgrowth; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Lovastatin; MAP Kinase Kinase 4; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Signal Transduction; Smad3 Protein; src-Family Kinases; Transforming Growth Factor beta1 | 2013 |
Downregulation of p38 MAPK involved in inhibition of LDL-induced proliferation of mesangial cells and matrix by curcumin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Proliferation; Cells, Cultured; Curcumin; Cyclooxygenase 2; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Extracellular Matrix; Gene Expression; Imidazoles; Lipoproteins, LDL; Matrix Metalloproteinase 2; Mesangial Cells; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction | 2013 |
Curcumin attenuates ischemia-like injury induced IL-1β elevation in brain microvascular endothelial cells via inhibiting MAPK pathways and nuclear factor-κB activation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cells, Cultured; Curcumin; Endothelial Cells; Enzyme Inhibitors; Glucose; Hypoxia; Imidazoles; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; L-Lactate Dehydrogenase; Male; Microvessels; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Time Factors | 2014 |
Curcumin inhibits the proliferation and invasiveness of MHCC97-H cells via p38 signaling pathway.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Curcumin; Drug Synergism; Humans; Imidazoles; Liver Neoplasms; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Phosphorylation; Pyridines | 2014 |
Curcumin suppresses JNK pathway to attenuate BPA-induced insulin resistance in LO2 cells.
Topics: Anthracenes; Benzhydryl Compounds; Cell Line; Curcumin; Enzyme Activation; Humans; Imidazoles; Inflammation; Insulin Resistance; MAP Kinase Signaling System; NF-kappa B; Oxidative Stress; Phenols; Pyridines; Pyrrolidines; Thiocarbamates | 2018 |
Hydrazinocurcumin Induces Apoptosis of Hepatocellular Carcinoma Cells Through the p38 MAPK Pathway.
Topics: Animals; Carcinoma, Hepatocellular; Cell Proliferation; Curcumin; Hep G2 Cells; Humans; Hydrazines; Imidazoles; Liver Neoplasms; Male; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Toxicity Tests, Subacute; Xenograft Model Antitumor Assays | 2021 |