sb 203580 has been researched along with colforsin in 25 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (colforsin) | Trials (colforsin) | Recent Studies (post-2010) (colforsin) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 13,460 | 46 | 1,298 |
| Protein | Taxonomy | sb 203580 (IC50) | colforsin (IC50) |
|---|---|---|---|
| nuclear receptor subfamily 0 group B member 1 | Homo sapiens (human) | 1.729 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.041 | |
| Adenylate cyclase type 1 | Homo sapiens (human) | 0.0955 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (8.00) | 18.2507 |
| 2000's | 21 (84.00) | 29.6817 |
| 2010's | 2 (8.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burns, CJ; Howell, SL; Jones, PM; Persaud, SJ | 1 |
| Brooks, DP; Francis, J; Nambi, P; Parameswaran, N; Pullen, M; Spielman, WS | 1 |
| Hansen, TO; Nielsen, FC; Rehfeld, JF | 1 |
| Lee, JK; Suh, HW; Won, JS | 1 |
| Caivano, M; Cohen, P; Gorgoni, B; Poli, V | 1 |
| Kandolf, R; Küpper, JH; Meyer, RG; Rodemann, HP | 1 |
| Eisen, TG; Smalley, KS | 1 |
| Gauldie, J; Howe, K; McKay, DM | 1 |
| Coulonval, K; Dumont, JE; Lamy, F; Perpete, S; Vandeput, F | 1 |
| Dhein, S; Hagendorff, A; Pfeiffer, D; Polontchouk, L; Salameh, A | 1 |
| Damiano, N; Galdiero, E; Galdiero, M; Longanella, A; Tortora, A; Vitiello, M | 1 |
| Itoh, M; Kakita, A; Miura, Y; Oiso, Y; Ono, Y; Suzuki, A | 1 |
| Ishisaki, A; Kanno, Y; Kozawa, O; Nakajima, K; Numata, O; Shibata, T; Tokuda, H | 1 |
| Egashira, K; Fukuyama, K; Ichiki, T; Iino, N; Masuda, S; Ono, H; Takeshita, A | 1 |
| Hirade, K; Ishisaki, A; Kanno, Y; Katagiri, Y; Kitajima, Y; Kozawa, O; Matsuno, H; Nakajima, K; Shu, E; Suga, H | 1 |
| Blondeau, JP; Corrèze, C; Pomérance, M | 1 |
| Creaven, BS; Egan, DA; Finn, GJ | 1 |
| Becker, TC; Cao, W; Collins, QF; Collins, S; Daniel, KW; Floering, L; Lupo, EG; Robidoux, J; Xiong, Y | 1 |
| Blume, N; Friedrichsen, BN; Gram, VK; Lee, YC; Møldrup, A; Neubauer, N; Nielsen, JH; Petersen, JS | 1 |
| Bhat, NR; Mohanty, SB; Zhang, P | 1 |
| Hanada, K; Iwasaki, Y; Kageyama, K; Nigawara, T; Sakihara, S; Suda, T; Takayasu, S | 1 |
| Caimmi, PP; Grossini, E; Mary, DA; Molinari, C; Ribichini, F; Uberti, F; Vacca, G | 1 |
| Derebecka-Holysz, N; Holysz, M; Lehmann, TP; Trzeciak, WH | 1 |
| Chetkovich, D; Golding, NL; Khurana, S; Lewis, AS; Liu, Z; Rosa, K | 1 |
| Campos-Toimil, M; Cuíñas, A; Elíes, J; Orallo, F | 1 |
25 other study(ies) available for sb 203580 and colforsin
| Article | Year |
|---|---|
The p38 mitogen-activated protein kinase cascade is not required for the stimulation of insulin secretion from rat islets of Langerhans.
Topics: Animals; Arsenites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cells, Cultured; Colforsin; Enzyme Inhibitors; Glucose; Homeostasis; Imidazoles; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Mitogen-Activated Protein Kinases; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Compounds; Sorbitol; Tetradecanoylphorbol Acetate; Vanadates | 1999 |
Mechanism of adrenomedullin-stimulated hyaluronic acid release in rat mesangial cells.
Topics: Adrenomedullin; Animals; Bucladesine; Cell Culture Techniques; Colforsin; Drug Interactions; Enzyme Inhibitors; Glomerular Mesangium; Hyaluronic Acid; Imidazoles; Kidney Cortex; Male; Peptides; Phosphotransferases; Pyridines; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1999 |
Cyclic AMP-induced neuronal differentiation via activation of p38 mitogen-activated protein kinase.
Topics: Animals; Cell Differentiation; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Fibroblast Growth Factor 2; Genes, Dominant; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Mutation; Neurites; Neurons; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Phosphorylation; Pyridines; Rats; Signal Transduction; Transfection; Tumor Cells, Cultured | 2000 |
Forskolin inhibits expression of inducible nitric oxide synthase mRNA via inhibiting the mitogen activated protein kinase in C6 cells.
Topics: Animals; Colforsin; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Glioma; Imidazoles; Isoquinolines; Lipopolysaccharides; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; RNA, Messenger; Sulfonamides; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
The induction of cyclooxygenase-2 mRNA in macrophages is biphasic and requires both CCAAT enhancer-binding protein beta (C/EBP beta ) and C/EBP delta transcription factors.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Butadienes; CCAAT-Enhancer-Binding Proteins; Cell Fractionation; Cell Line; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; DNA; Enzyme Induction; Enzyme Inhibitors; Imidazoles; Isoenzymes; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Models, Biological; NF-kappa B; Nitriles; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Binding; Pyridines; RNA, Messenger; Transcription Factors | 2001 |
Early growth response-1 gene (Egr-1) promoter induction by ionizing radiation in U87 malignant glioma cells in vitro.
Topics: Androstadienes; Anisomycin; Blotting, Western; Colforsin; DNA-Binding Proteins; Early Growth Response Protein 1; Epidermal Growth Factor; Flavonoids; Glioma; Humans; Imidazoles; Immediate-Early Proteins; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Pyridines; Suramin; Transcription Factors; Wortmannin | 2002 |
Differentiation of human melanoma cells through p38 MAP kinase is associated with decreased retinoblastoma protein phosphorylation and cell cycle arrest.
Topics: alpha-MSH; Cell Differentiation; Colforsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; G1 Phase; Humans; Imidazoles; Kinetics; MAP Kinase Signaling System; Melanins; Melanoma; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Phosphorylation; Protein Processing, Post-Translational; Pyridines; Retinoblastoma Protein; Tumor Cells, Cultured | 2002 |
TGF-beta effects on epithelial ion transport and barrier: reduced Cl- secretion blocked by a p38 MAPK inhibitor.
Topics: Biological Transport; Chlorides; Colforsin; Colon; Cyclic AMP; Electric Conductivity; Enzyme Inhibitors; Gene Transfer Techniques; Humans; Imidazoles; Intestinal Mucosa; Ions; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Permeability; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Transforming Growth Factor beta; Tumor Cells, Cultured | 2002 |
Role of the different mitogen-activated protein kinase subfamilies in the stimulation of dog and human thyroid epithelial cell proliferation by cyclic adenosine 5'-monophosphate and growth factors.
Topics: Animals; Arsenites; Carcinogens; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Dogs; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Flavonoids; Hepatocyte Growth Factor; Humans; Hypoglycemic Agents; Imidazoles; Insulin; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Sodium Compounds; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 2003 |
Chronic regulation of the expression of the gap junction protein connexin 43 in transfected HeLa cells.
Topics: Adenylyl Cyclases; Blotting, Western; Colforsin; Connexin 43; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Fluorescent Antibody Technique; Gap Junctions; Gene Expression Regulation; HeLa Cells; Humans; Imidazoles; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transfection; Tumor Necrosis Factor-alpha | 2003 |
Induction of cytokine mRNA expression in U937 cells by Salmonella typhimurium porins is regulated by different phosphorylation pathways.
Topics: Colforsin; Cytokines; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Lipopolysaccharides; Monocytes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Porins; Proto-Oncogene Proteins c-raf; Pyridines; RNA, Messenger; Salmonella typhimurium; U937 Cells | 2005 |
Possible involvement of p38 MAP kinase in prostaglandin E1-induced ALP activity in osteoblast-like cells.
Topics: Adenylyl Cyclases; Alkaline Phosphatase; Alprostadil; Animals; Bucladesine; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Imidazoles; Isoquinolines; Mice; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Sulfonamides | 2004 |
Involvement of SAPK/JNK in prostaglandin E(1)-induced VEGF synthesis in osteoblast-like cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Anthracenes; Cell Line; Colforsin; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-jun; Pyridines; Vascular Endothelial Growth Factor A | 2004 |
cAMP-response element-binding protein mediates tumor necrosis factor-alpha-induced vascular smooth muscle cell migration.
Topics: Cell Movement; Cells, Cultured; Colforsin; Coronary Vessels; CREB-Binding Protein; Genes, Dominant; Genes, fos; Humans; Imidazoles; Ionomycin; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phosphoserine; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Pyridines; rac1 GTP-Binding Protein; Recombinant Fusion Proteins; Trans-Activators; Tumor Necrosis Factor-alpha | 2004 |
Akt regulates thrombin-induced HSP27 phosphorylation in aortic smooth muscle cells: function at a point downstream from p38 MAP kinase.
Topics: Adenylyl Cyclases; Animals; Aorta; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Heat-Shock Proteins; Imidazoles; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Rats; Thrombin | 2005 |
p38 mitogen-activated protein kinase contributes to cell cycle regulation by cAMP in FRTL-5 thyroid cells.
Topics: Animals; CDC2-CDC28 Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Cyclin-Dependent Kinase 2; Enzyme Inhibitors; G1 Phase; Hypoglycemic Agents; Imidazoles; Insulin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; S Phase; Signal Transduction; Threonine; Thyroid Gland; Tyrosine | 2005 |
Activation of mitogen activated protein kinase pathways and melanogenesis by novel nitro-derivatives of 7-hydroxycomarin in human malignant melanoma cells.
Topics: Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; MAP Kinase Signaling System; Melanins; Melanoma; Mitogen-Activated Protein Kinases; Monophenol Monooxygenase; Nitro Compounds; Pyridines; Umbelliferones | 2005 |
p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.
Topics: Acetylcysteine; Adenoviridae; Animals; Cell Line, Tumor; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 1; Disease Models, Animal; Enzyme Inhibitors; Gene Silencing; Glucagon; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Hepatocytes; Imidazoles; Liver; Mice; p38 Mitogen-Activated Protein Kinases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphoenolpyruvate Carboxykinase (GTP); Phosphorylation; Promoter Regions, Genetic; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Streptozocin; Trans-Activators; Transcription Factors; Transfection | 2005 |
Stimulation of pancreatic beta-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways.
Topics: Adenylyl Cyclases; Androstadienes; Animals; Animals, Newborn; Cell Line; Cell Proliferation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Enzyme Activation; Flavonoids; Gastric Inhibitory Polypeptide; Glucagon-Like Peptide 1; Human Growth Hormone; Imidazoles; Insulin-Secreting Cells; Isoquinolines; Liraglutide; Mitogen-Activated Protein Kinase Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Rats; Signal Transduction; Stimulation, Chemical; Sulfonamides; Transcription, Genetic; Transduction, Genetic; Wortmannin | 2006 |
p38 MAP kinase regulation of oligodendrocyte differentiation with CREB as a potential target.
Topics: Animals; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Imidazoles; Myelin Basic Protein; Myelin Proteolipid Protein; Myelin-Associated Glycoprotein; Oligodendroglia; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; RNA, Messenger | 2007 |
Involvement of regulatory elements on corticotropin-releasing factor gene promoter in hypothalamic 4B cells.
Topics: Anthracenes; Cell Line; Chromones; Colforsin; Corticotropin-Releasing Hormone; Dexamethasone; Flavonoids; Genes, Reporter; Humans; Hypothalamus; Imidazoles; Isoquinolines; Morpholines; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyridines; Regulatory Elements, Transcriptional; Sequence Deletion; Sulfonamides; Transfection | 2008 |
Urocortin II induces nitric oxide production through cAMP and Ca2+ related pathways in endothelial cells.
Topics: Androstadienes; Animals; Aorta; Blotting, Western; Butadienes; Calcimycin; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Dideoxyadenosine; Endothelial Cells; Imidazoles; Ionophores; Mitogen-Activated Protein Kinase 3; Nitric Oxide; Nitriles; Oncogene Protein v-akt; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Peptides, Cyclic; Pyridines; Signal Transduction; Swine; Urocortins; Wortmannin | 2009 |
TGF-beta inhibits CYP17 transcription in H295R cells acting via activin receptor-like kinase 5.
Topics: Activin Receptors; Adrenal Cortex; Benzamides; Cell Line; Colforsin; Cytochromes b5; Dichlororibofuranosylbenzimidazole; Dioxoles; Humans; Imidazoles; MAP Kinase Kinase 1; NADPH-Ferrihemoprotein Reductase; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Transforming Growth Factor beta | 2009 |
An essential role for modulation of hyperpolarization-activated current in the development of binaural temporal precision.
Topics: Age Factors; Analysis of Variance; Androstadienes; Animals; Biophysical Phenomena; Bucladesine; Colforsin; Cyclic Nucleotide-Gated Cation Channels; Electric Stimulation; Enzyme Inhibitors; Female; Gene Expression Regulation, Developmental; Gerbillinae; Imidazoles; In Vitro Techniques; Ion Channel Gating; Male; Neurons; Olivary Nucleus; Patch-Clamp Techniques; Pyridines; Pyrimidines; Wortmannin | 2012 |
Cyclic AMP relaxation of rat aortic smooth muscle is mediated in part by decrease of depletion of intracellular Ca(2+) stores and inhibition of capacitative calcium entry.
Topics: Animals; Aorta, Thoracic; Calcium; Colforsin; Cyclic AMP; Imidazoles; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nifedipine; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Phosphodiesterase 4 Inhibitors; Pyridines; Rats; Rats, Inbred WKY; Rolipram; Vasodilation; Vasodilator Agents; Verapamil | 2013 |