Compounds > sb 203580
Page last updated: 2024-09-05

sb 203580 and cilomilast

sb 203580 has been researched along with cilomilast in 2 studies

Compound Research Comparison

Studies
(sb 203580)		Trials
(sb 203580)		Recent Studies (post-2010)
(sb 203580)		Studies
(cilomilast)		Trials
(cilomilast)		Recent Studies (post-2010) (cilomilast)
3,48941,1371621342

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)cilomilast (IC50)
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.018
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.018
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.018
Chain A, cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.018
Chain A, cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.018
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)2.3453
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)2.3453
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)2.3453
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Rattus norvegicus (Norway rat)0.113
cAMP-specific 3',5'-cyclic phosphodiesterase 4CRattus norvegicus (Norway rat)0.113
cAMP-specific 3',5'-cyclic phosphodiesterase 4BRattus norvegicus (Norway rat)0.1623
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)0.3113
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.062
cAMP-specific 3',5'-cyclic phosphodiesterase 4ARattus norvegicus (Norway rat)0.113
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)2.3453
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.4623
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)0.818
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.4642
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)4.259
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)10
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.12
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AHomo sapiens (human)2.3453
cAMP-specific 3',5'-cyclic phosphodiesterase 7BHomo sapiens (human)2.3453
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10AHomo sapiens (human)2.3453

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barlow, DJ; Ehrman, TM; Hylands, PJ1
Allen, JM; Bertrand, C; Jacob, C; Lagente, V; Szilagyi, C1

Other Studies

2 other study(ies) available for sb 203580 and cilomilast

ArticleYear
In silico search for multi-target anti-inflammatories in Chinese herbs and formulas.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Anti-Inflammatory Agents; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Databases, Factual; Drug Design; Drugs, Chinese Herbal; Enzyme Inhibitors; JNK Mitogen-Activated Protein Kinases; Medicine, Chinese Traditional; Models, Chemical; Models, Molecular; Molecular Conformation; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase 4 Inhibitors; Structure-Activity Relationship

2010
Role of PDE4 in superoxide anion generation through p44/42MAPK regulation: a cAMP and a PKA-independent mechanism.
    British journal of pharmacology, 2004, Volume: 143, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Bronchoalveolar Lavage Fluid; Bucladesine; CREB-Binding Protein; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Flavonoids; Gene Expression Regulation, Enzymologic; Imidazoles; Lipopolysaccharides; Macrophages; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitriles; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-raf; Pyridines; Rats; Rats, Wistar; Reactive Oxygen Species; Rolipram; Superoxides; Trans-Activators

2004