Page last updated: 2024-09-05

sb 203580 and chloroquine

sb 203580 has been researched along with chloroquine in 7 studies

Compound Research Comparison

Studies
(sb 203580)
Trials
(sb 203580)
Recent Studies (post-2010)
(sb 203580)
Studies
(chloroquine)
Trials
(chloroquine)
Recent Studies (post-2010) (chloroquine)
3,48941,13716,4057634,029

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)chloroquine (IC50)
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonasePlasmodium berghei43
Spike glycoproteinBetacoronavirus England 15.47
Replicase polyprotein 1abBetacoronavirus England 15.47
Transmembrane protease serine 2Homo sapiens (human)5.47
Dihydrofolate reductase Bos taurus (cattle)0.0301
Amyloid-beta precursor proteinHomo sapiens (human)7
Histidine-rich protein PFHRP-IIPlasmodium falciparum (malaria parasite P. falciparum)0.2383
Procathepsin LHomo sapiens (human)5.47
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirus5.47
Replicase polyprotein 1abHuman coronavirus 229E5.47
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirus5.47
Spike glycoproteinSevere acute respiratory syndrome coronavirus 23.58
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 26.375
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)1.5
Serine/threonine-protein kinase mTORHomo sapiens (human)0.27
Beta-secretase 1Homo sapiens (human)7
Spike glycoproteinSevere acute respiratory syndrome-related coronavirus5.47
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)2.503
Angiotensin-converting enzyme 2 Homo sapiens (human)6.235
Cysteine proteinase falcipain 2a Plasmodium falciparum (malaria parasite P. falciparum)0.02
Cysteine proteinase falcipain 2a Plasmodium falciparum (malaria parasite P. falciparum)0.2

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's6 (85.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Imai, AM; Kono, M; Kuriyama, T; Saito, K; Shirasawa, H; Tatsumi, K1
Cheng, YC; Liang, SM; Ravindran, C1
Anderson, TJ; Brumlik, MJ; Curiel, TJ; Kious, MJ; Nkhoma, S; Patterson, TF; Siekierka, JJ; Thompson, GR1
Radhika, A; Sudhakaran, PR1
Cooper, PR; He, W; Huang, P; Smith, AJ; Wang, ZH; Yu, Q; Zhang, J; Zhu, QL1
Kang, JW; Lee, SM; Shin, JK1
Li, X; Liu, F; Luo, J; Yang, H; Yang, Y; Zhao, Q1

Other Studies

7 other study(ies) available for sb 203580 and chloroquine

ArticleYear
Inhibition of human coronavirus 229E infection in human epithelial lung cells (L132) by chloroquine: involvement of p38 MAPK and ERK.
    Antiviral research, 2008, Volume: 77, Issue:2

    Topics: Antiviral Agents; Cell Line; Chloroquine; Coronavirus 229E, Human; Cytopathogenic Effect, Viral; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Imidazoles; Lung; p38 Mitogen-Activated Protein Kinases; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Virus Replication

2008
CpG-ODNs induces up-regulated expression of chemokine CCL9 in mouse macrophages and microglia.
    Cellular immunology, 2010, Volume: 260, Issue:2

    Topics: Amyloid beta-Peptides; Animals; Cell Line; Chemokines, CC; Chloroquine; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flavonoids; Flow Cytometry; Imidazoles; Macrophage Inflammatory Proteins; Macrophages; Mice; Microglia; Mitogen-Activated Protein Kinases; Myeloid Differentiation Factor 88; Oligodeoxyribonucleotides; Peptide Fragments; Pyridines; Receptors, CCR1; Reverse Transcriptase Polymerase Chain Reaction; Toll-Like Receptor 9; Transfection; Up-Regulation

2010
Human p38 mitogen-activated protein kinase inhibitor drugs inhibit Plasmodium falciparum replication.
    Experimental parasitology, 2011, Volume: 128, Issue:2

    Topics: Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Erythrocytes; Humans; Imidazoles; Indoles; Inhibitory Concentration 50; Mefloquine; p38 Mitogen-Activated Protein Kinases; Plasmodium falciparum; Protein Kinase Inhibitors; Pyridines

2011
Upregulation of macrophage-specific functions by oxidized LDL: lysosomal degradation-dependent and -independent pathways.
    Molecular and cellular biochemistry, 2013, Volume: 372, Issue:1-2

    Topics: Acetylcysteine; Cell Differentiation; Cells, Cultured; Chloroquine; Chromones; Copper Sulfate; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Gene Expression; Humans; Imidazoles; Leukocytes, Mononuclear; Lipoproteins, LDL; Lysosomes; Macrophages; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Morpholines; Naphthalenes; NF-kappa B; Oxidation-Reduction; PPAR gamma; Proteolysis; Pyridines; Signal Transduction; Transcription Factor AP-1; Transcriptional Activation; Up-Regulation

2013
CpG ODN-induced matrix metalloproteinase-13 expression is mediated via activation of the ERK and NF-κB signalling pathways in odontoblast cells.
    International endodontic journal, 2013, Volume: 46, Issue:7

    Topics: Animals; Anthracenes; Cell Line; Chloroquine; CpG Islands; Dental Pulp; Extracellular Signal-Regulated MAP Kinases; I-kappa B Proteins; Imidazoles; MAP Kinase Signaling System; Matrix Metalloproteinase 13; Mice; Mitogen-Activated Protein Kinases; Myeloid Differentiation Factor 88; NF-kappa B; Nitriles; Odontoblasts; Oligodeoxyribonucleotides; Phosphorylation; Pyridines; Pyrrolidines; Real-Time Polymerase Chain Reaction; Signal Transduction; Sulfones; Thiocarbamates; Toll-Like Receptor 9; Tosylphenylalanyl Chloromethyl Ketone; Transcription Factor RelA

2013
Enhanced nitric oxide-mediated autophagy contributes to the hepatoprotective effects of ischemic preconditioning during ischemia and reperfusion.
    Nitric oxide : biology and chemistry, 2016, 08-31, Volume: 58

    Topics: Animals; Autophagy; Chloroquine; Guanidines; Imidazoles; Ischemia; Ischemic Preconditioning; Liver; Liver Diseases; Male; Mice, Inbred C57BL; Microtubule-Associated Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Pyridines; Reperfusion Injury

2016
Naringenin Exerts Cardiovascular Protective Effect in a Palmitate-Induced Human Umbilical Vein Endothelial Cell Injury Model via Autophagy Flux Improvement.
    Molecular nutrition & food research, 2019, Volume: 63, Issue:24

    Topics: Acetylcysteine; Anthracenes; Apoptosis; Autophagy; Cardiotonic Agents; Chloroquine; Endothelium, Vascular; Flavanones; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; MAP Kinase Signaling System; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Palmitates; Pyridines; Reactive Oxygen Species

2019